Fasciculation and elongation protein zeta 1 (zygin I) (FEZ1)

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UGID:165580 UniGene Hs.224008 Homo sapiens (human) FEZ1

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Fasciculation and elongation protein zeta 1 (zygin I) (FEZ1)

Human protein-coding gene FEZ1. Represented by 276 ESTs from 138 cDNA libraries. Corresponds to reference sequence NM_005103.4. [UniGene 165580 - Hs.224008]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_001145893.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: fasciculation and elongation protein zeta-1 isoform 8	P. troglodytes	100.0	391
NP_005094.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	FEZ1 gene product	H. sapiens	100.0	391
NP_001091077.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	FEZ1 gene product	E. caballus	100.0	217
XP_001111094.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: fasciculation and elongation protein zeta-1 isoform 8	M. mulatta	99.7	391
NP_898994.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Fez1 gene product	M. musculus	96.4	391
NP_001085822.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	fasciculation and elongation protein zeta 1 (zygin I)	X. laevis	82.4	391
NP_998561.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	fez1 gene product	D. rerio	77.4	393
Other hits (2 of 18) [Show all]		Species	Id(%)	Len(aa)
XP_003910957.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: fasciculation and elongation protein zeta-1	P. anubis	99.1	345
XP_002708731.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: zygin 1	O. cuniculus	99.0	391

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; eye; thymus; uncharacterized tissue; muscle; placenta; mixed; prostate; lung; stomach; bone marrow; embryonic tissue; uterus; pharynx; pancreas; testis; vascular; intestine; spinal cord; mammary gland; spleen; kidney; skin; ovary; heart; nerve; blood; connective tissue; liver; parathyroid; lymph node; pineal gland; umbilical cord

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11q24.2
UniSTS entry:	Chr 11	G43640
UniSTS entry:	Chr 11	D11S3963E

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_005103.4	Homo sapiens fasciculation and elongation protein zeta 1 (zygin I) (FEZ1), transcript variant 1, mRNA	PA
CR456817.1	Homo sapiens full open reading frame cDNA clone RZPDo834G0418D for gene FEZ1, fasciculation and elongation protein zeta 1 (zygin I); complete cds, incl. stopcodon	P
CR541954.1	Homo sapiens full open reading frame cDNA clone RZPDo834G0234D for gene FEZ1, fasciculation and elongation protein zeta 1 (zygin I); complete cds, without stopcodon	P
BC009545.1	Homo sapiens fasciculation and elongation protein zeta 1 (zygin I), mRNA (cDNA clone MGC:10085 IMAGE:3897353), complete cds	PA
AK296554.1	Homo sapiens cDNA FLJ60632 complete cds, highly similar to Fasciculation and elongation protein zeta 1	P
U69139.1	Human zyginI mRNA, complete cds	P
U60060.1	Human FEZ1 mRNA, complete cds	PA

EST sequences (10 of 276) [Show all sequences]

AA927731.1	Clone IMAGE:1552753	uncharacterized tissue	3' read	A
AI025153.1	Clone IMAGE:1639438	testis	3' read	A
T06001.1	Clone HFBDK84	brain
AI078275.1	Clone IMAGE:1676788	embryonic tissue	3' read	A
AI150749.1	Clone IMAGE:1708438	heart	3' read	A
R25079.1	Clone IMAGE:20079	brain	5' read
BX091209.1	Clone IMAGp998G02273_;_IMAGE:46305	brain		A
AI265849.1	Clone IMAGE:1932220	mixed	3' read	A
AI268199.1	Clone IMAGE:1880606	mixed	3' read	A
AI085491.1	Clone IMAGE:1750545	brain	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria