> Chromodomain helicase DNA binding protein 2 (CHD2)
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UGID:165143     UniGene Hs.220864     Homo sapiens (human)   CHD2
Chromodomain helicase DNA binding protein 2 (CHD2)

Human protein-coding gene CHD2. Represented by 569 ESTs from 276 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 165143 - Hs.220864]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001262.3 CHD2 gene product H. sapiens 100.0 1827
XP_001170676.2 PREDICTED: chromodomain-helicase-DNA-binding protein 2 isoform 4 P. troglodytes 100.0 1317
XP_002808499.1 PREDICTED: LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 2-like M. mulatta 99.8 1805
NP_001074814.2 chromodomain helicase DNA binding protein 2 M. musculus 98.1 1826
NP_001121770.2 chromodomain helicase DNA binding protein 1 D. rerio 72.2 1691
NP_491994.2 Protein CHD-1 C. elegans 64.2 965
NP_477197.1 Chromodomain-helicase-DNA-binding protein 1, isoform A D. melanogaster 58.7 1780
XP_001703254.1 chromodomain-helicase-DNA-binding protein C. reinhardtii 56.0 780
NP_001080504.1 chromodomain helicase DNA binding protein 4 X. laevis 54.2 550
NP_014948.1 Isw2p S. cerevisiae 51.6 541
XP_956548.2 chromatin remodelling complex ATPase chain ISW1 N. crassa 49.2 530
NP_568365.2 chromatin remodeling factor17 A. thaliana 49.2 559
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
XP_536179.2 PREDICTED: chromodomain-helicase-DNA-binding protein 2 isoform 1 C. lupus familiaris 99.1 1826
XP_004017778.1 PREDICTED: chromodomain-helicase-DNA-binding protein 2 O. aries 98.6 1826

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; liver; uncharacterized tissue; lung; ovary; muscle; embryonic tissue; blood; mammary gland; vascular; pharynx; mouth; testis; pancreas; kidney; uterus; prostate; intestine; thymus; placenta; eye; skin; bladder; cervix; pineal gland; lymph; esophagus; trachea; ascites; heart; bone; stomach; connective tissue; thyroid; larynx; lymph node; spleen; bone marrow; epididymis; tonsil; ganglia; adrenal gland; peritoneum; parathyroid; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q26
UniSTS entry: Chr 15 RH93743
UniSTS entry: Chr 15 RH80079
UniSTS entry: Chr 15 WI-20731 [Map Viewer]
UniSTS entry: Chr 15 RH66633
UniSTS entry: Chr 15 RH44878
UniSTS entry: Chr 15 D15S1494
UniSTS entry: Chr 15 CHD2
UniSTS entry: Chr 15 A003M08 [Map Viewer]
UniSTS entry: Chr 15 RH46033 [Map Viewer]
UniSTS entry: Chr 15 SHGC-37648
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BC047036.1 Homo sapiens, clone IMAGE:4940955, mRNA A
BT007050.1 Homo sapiens chromodomain helicase DNA binding protein 2 mRNA, complete cds P
BX537626.1 Homo sapiens mRNA; cDNA DKFZp686E01200 (from clone DKFZp686E01200) A
NM_001271.3 Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA PA
AY429528.1 Homo sapiens CHD2v_2 mRNA sequence; alternatively spliced P
AY429527.1 Homo sapiens CHD2v_1 mRNA sequence; alternatively spliced P
DQ088986.1 Homo sapiens CDH2 isoform 2 mRNA, partial cds P
DQ088985.1 Homo sapiens CDH2 isoform 1 mRNA, partial cds P
BC107885.1 Homo sapiens chromodomain helicase DNA binding protein 2, mRNA (cDNA clone IMAGE:6668384) PA
NM_001042572.2 Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 2, mRNA PA
BC007347.2 Homo sapiens chromodomain helicase DNA binding protein 2, mRNA (cDNA clone IMAGE:3050321), complete cds PA
AK292850.1 Homo sapiens cDNA FLJ76689 partial cds, highly similar to Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), mRNA P
BC020810.1 Homo sapiens chromodomain helicase DNA binding protein 2, mRNA (cDNA clone IMAGE:4293394), complete cds PA
AK095933.1 Homo sapiens cDNA FLJ38614 fis, clone HEART2006521
AL831836.1 Homo sapiens mRNA; cDNA DKFZp547I1315 (from clone DKFZp547I1315) PA
AK295909.1 Homo sapiens cDNA FLJ53879 complete cds, highly similar to Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) PA
AF006514.1 Homo sapiens CHD2 mRNA, complete cds P

EST sequences (10 of 569) [Show all sequences]

AA907556.1 Clone IMAGE:1540515 mixed 3' read A
R18403.1 Clone IMAGE:31148 brain 5' read
AI022394.1 Clone IMAGE:1652395 mixed 3' read
AI022396.1 Clone IMAGE:1652399 mixed 3' read
T05823.1 Clone HFBDG87 brain
AI053974.1 Clone IMAGE:1861351 ovary 3' read P
AI054391.1 Clone IMAGE:1862444 ovary 3' read PA
AI066439.1 Clone IMAGE:1594411 intestine 3' read A
AI073737.1 Clone IMAGE:1665170 skin 3' read A
AI076127.1 Clone IMAGE:1673318 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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