> Tyrosyl-tRNA synthetase (YARS)
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UGID:164747     UniGene Hs.213264     Homo sapiens (human)   YARS Order cDNA clone, Links
Tyrosyl-tRNA synthetase (YARS)

Human protein-coding gene YARS. Represented by 1763 ESTs from 411 cDNA libraries. Corresponds to reference sequence NM_003680.3. [UniGene 164747 - Hs.213264]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001164500.1 PREDICTED: tyrosine--tRNA ligase, cytoplasmic isoform 10 P. troglodytes 100.0 527
NP_003671.1 YARS gene product H. sapiens 100.0 527
XP_001104797.2 PREDICTED: tyrosyl-tRNA synthetase, cytoplasmic isoform 1 M. mulatta 99.8 496
XP_003891574.1 PREDICTED: tyrosine--tRNA ligase, cytoplasmic P. anubis 99.6 527
NP_598912.3 tyrosine--tRNA ligase, cytoplasmic M. musculus 98.1 527
NP_958473.1 yars gene product D. rerio 89.2 528
NP_001080746.1 tyrosine--tRNA ligase, cytoplasmic X. laevis 88.0 527
NP_648895.1 Tyrosyl-tRNA synthetase D. melanogaster 81.5 518
NP_740947.2 Protein Y105E8A.19 C. elegans 70.9 361
NP_011701.3 tyrosine--tRNA ligase TYS1 S. cerevisiae 64.9 376
XP_958548.2 tyrosyl-tRNA synthetase N. crassa 59.9 384
XP_001690203.1 predicted protein C. reinhardtii 54.7 160
NP_193114.1 methionyl-tRNA synthetase A. thaliana 51.9 189
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_003356343.1 PREDICTED: tyrosyl-tRNA synthetase, cytoplasmic S. scrofa 97.9 527
XP_002720753.1 PREDICTED: tyrosyl-tRNA synthetase O. cuniculus 97.9 527

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; eye; lung; kidney; skin; uterus; placenta; intestine; lymph; connective tissue; prostate; mixed; spleen; liver; embryonic tissue; thymus; blood; ascites; adrenal gland; mammary gland; vascular; bladder; bone marrow; ovary; muscle; stomach; bone; cervix; mouth; heart; pancreas; esophagus; trachea; umbilical cord; thyroid; lymph node; larynx; epididymis; adipose tissue; parathyroid; pharynx; nerve; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p35.1
UniSTS entry: Chr 1 SHGC-74542 [Map Viewer]
UniSTS entry: Chr 1 SHGC-74549 [Map Viewer]
UniSTS entry: Chr 1 SHGC-74550 [Map Viewer]
UniSTS entry: Chr 1 SHGC-74484 [Map Viewer]
UniSTS entry: Chr 1 RH64745
UniSTS entry: Chr 1 SHGC-74538 [Map Viewer]
UniSTS entry: Chr 1 STS-R16166 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AK125213.1 Homo sapiens cDNA FLJ43223 fis, clone FEBRA2026984, highly similar to Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) P
NM_003680.3 Homo sapiens tyrosyl-tRNA synthetase (YARS), mRNA PA
AK223608.1 Homo sapiens mRNA for tyrosyl-tRNA synthetase variant, clone: FCC132F02 P
AK026535.1 Homo sapiens cDNA: FLJ22882 fis, clone KAT03587, highly similar to HSU89436 Human tyrosyl-tRNA synthetase mRNA PA
BC001933.1 Homo sapiens tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:4000 IMAGE:2821104), complete cds PA
BC004151.2 Homo sapiens tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:2382 IMAGE:2821104), complete cds PA
BC016689.1 Homo sapiens tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:21917 IMAGE:4386850), complete cds PA
U40714.1 Human tyrosyl-tRNA synthetase mRNA, complete cds P
U89436.1 Human tyrosyl-tRNA synthetase mRNA, complete cds P

EST sequences (10 of 1763) [Show all sequences]

R16166.1 Clone IMAGE:53277 brain 3' read
R15426.1 Clone IMAGE:53277 brain 5' read P
AA973034.1 Clone IMAGE:1577912 mixed 3' read P
AA977086.1 Clone IMAGE:1587181 uncharacterized tissue 3' read PA
AI015327.1 Clone IMAGE:1618763 testis 3' read A
R18984.1 Clone IMAGE:33689 brain 5' read P
AI080604.1 Clone IMAGE:1680441 skin 3' read A
AI090505.1 Clone IMAGE:1692085 heart 3' read A
AI090526.1 Clone IMAGE:1692109 heart 3' read A
AI092564.1 Clone IMAGE:1683441 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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