> Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B)
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UGID:164139     UniGene Hs.210870     Homo sapiens (human)   SEMA5B
Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B)

Human protein-coding gene SEMA5B. Represented by 112 ESTs from 53 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 164139 - Hs.210870]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001243276.1 SEMA5B gene product H. sapiens 100.0 1204
NP_038689.2 Sema5b gene product M. musculus 96.2 1092
NP_001079991.1 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B precursor X. laevis 81.2 1080
XP_684379.2 PREDICTED: semaphorin-5B D. rerio 73.2 1141
NP_995856.1 Sema-2a, isoform D D. melanogaster 48.1 295
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_003894066.1 PREDICTED: semaphorin-5B P. anubis 99.0 1056
XP_002802721.1 PREDICTED: semaphorin-5B-like M. mulatta 98.9 1056

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; testis; ovary; kidney; mixed; eye; uterus; intestine; heart; mammary gland; lung; placenta; mouth; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q21.1
UniSTS entry: Chr 3 STS-AA026150
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AK001234.1 Homo sapiens cDNA FLJ10372 fis, clone NT2RM2001930 P
BC077726.1 Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B, mRNA (cDNA clone MGC:78583 IMAGE:6597493), complete cds PA
AB040878.1 Homo sapiens mRNA for KIAA1445 protein, partial cds P
NM_001031702.3 Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 1, mRNA PA
BC002776.2 Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B, mRNA (cDNA clone IMAGE:3621447) PA
AK291407.1 Homo sapiens cDNA FLJ77468 complete cds, highly similar to Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 1, mRNA P
AK309848.1 Homo sapiens cDNA, FLJ99889 P
AK309834.1 Homo sapiens cDNA, FLJ99875 P
AK091481.1 Homo sapiens cDNA FLJ34162 fis, clone FCBBF3014260, highly similar to SEMAPHORIN 5B PRECURSOR P
AK295619.1 Homo sapiens cDNA FLJ55460 complete cds, highly similar to Semaphorin-5B precursor P
AK294528.1 Homo sapiens cDNA FLJ59503 complete cds, highly similar to Semaphorin-5B precursor P
NM_001256348.1 Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 4, mRNA PA
NM_001256347.1 Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 3, mRNA PA
NM_001256346.1 Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 2, mRNA PA
NR_046079.1 Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 5, non-coding RNA PA

EST sequences (10 of 112) [Show all sequences]

AI077481.1 Clone IMAGE:1678643 mixed 3' read P
AI082777.1 Clone IMAGE:1662044 mixed 3' read P
AI081226.1 Clone IMAGE:1662253 mixed 3' read P
CB045671.1 Clone IMAGE:3218518 intestine 5' read P
AI186520.1 Clone IMAGE:1731437 heart 3' read P
AI371424.1 Clone IMAGE:1915238 kidney 3' read A
AI479935.1 Clone IMAGE:2163739 brain 3' read A
AI500330.1 Clone IMAGE:2165873 brain 3' read A
AI689552.1 Clone IMAGE:2276255 uterus 3' read A
AI932244.1 Clone IMAGE:2466784 brain 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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