MCF.2 cell line derived transforming sequence-like 2 (MCF2L2)

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UGID:163561 UniGene Hs.208267 Homo sapiens (human) MCF2L2

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MCF.2 cell line derived transforming sequence-like 2 (MCF2L2)

Human protein-coding gene MCF2L2. Represented by 109 ESTs from 75 cDNA libraries. Corresponds to reference sequence NM_015078.2. [UniGene 163561 - Hs.208267]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_055893.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MCF2L2 gene product	H. sapiens	100.0	1113
XP_001921389.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: guanine nucleotide exchange factor DBS	D. rerio	59.6	948
NP_001152957.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Mcf2l gene product	M. musculus	55.5	667
Other hits (2 of 20) [Show all]		Species	Id(%)	Len(aa)
XP_003310188.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable guanine nucleotide exchange factor MCF2L2	P. troglodytes	99.5	1113
XP_003894816.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable guanine nucleotide exchange factor MCF2L2 isoform 2	P. anubis	97.0	1085

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; mouth; pancreas; embryonic tissue; mixed; prostate; vascular; larynx; uncharacterized tissue; muscle; uterus; liver; kidney; pharynx; placenta; intestine; mammary gland; testis; stomach; lung; skin; trachea; salivary gland; connective tissue; lymph node; adipose tissue; bone; thyroid

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	3
Map position:	3q27.1
UniSTS entry:	Chr 1	D8S2278
UniSTS entry:	Chr 3	WI-13813	[Map Viewer]
UniSTS entry:	Chr 1	PMC156606P4
UniSTS entry:	Chr 1	PMC156606P3
UniSTS entry:	Chr 1	D11S2921
UniSTS entry:	Chr 1	PMC156606P2
UniSTS entry:	Chr 1	D16S325
UniSTS entry:	Chr 3	SHGC-149665
UniSTS entry:	Chr 1	G44365
UniSTS entry:	Chr 1	D11S3492

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AY172737.1	Homo sapiens Rho family guanine-nucleotide exchange factor mRNA, complete cds	P
NM_015078.2	Homo sapiens MCF.2 cell line derived transforming sequence-like 2 (MCF2L2), mRNA	P
AB020668.1	Homo sapiens mRNA for KIAA0861 protein, partial cds	P
BX649003.1	Homo sapiens mRNA; cDNA DKFZp686K0690 (from clone DKFZp686K0690)	PA
BX648525.1	Homo sapiens mRNA; cDNA DKFZp686H2395 (from clone DKFZp686H2395)	PA
BX647790.1	Homo sapiens mRNA; cDNA DKFZp686K0886 (from clone DKFZp686K0886)	PA
AK124500.1	Homo sapiens cDNA FLJ42509 fis, clone BRACE2044286, moderately similar to GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS	P
BC064632.1	Homo sapiens MCF.2 cell line derived transforming sequence-like 2, mRNA (cDNA clone MGC:70350 IMAGE:5750039), complete cds	PA
AK310962.1	Homo sapiens cDNA, FLJ18004	P
BC029074.2	Homo sapiens MCF.2 cell line derived transforming sequence-like 2, mRNA (cDNA clone IMAGE:4214717), partial cds	PA
AK301698.1	Homo sapiens cDNA FLJ51363 complete cds, highly similar to Homo sapiens MCF.2 cell line derived transforming sequence-like 2 (MCF2L2), mRNA	P

EST sequences (10 of 109) [Show all sequences]

T06006.1	Clone HFBDK90	brain
T06007.1	Clone HFBDK90	brain
R24293.1	Clone IMAGE:33872	brain	5' read
BX109053.1	Clone IMAGp998D164492_;_IMAGE:1836639	testis		P
AI208983.1	Clone IMAGE:1836639	testis	3' read	PA
CB160964.1	Clone L18POOL1n1-24-A06	liver	5' read
CB163019.1	Clone L18POOL1n1-44-C08	liver	5' read
CB133350.1	Clone L9SNU354-11-D02	liver	5' read
AI243125.1	Clone IMAGE:1845841	mixed	3' read
AI370362.1	Clone IMAGE:1967769	lymph node	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria