> Estrogen receptor 1 (ESR1)
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UGID:163517     UniGene Hs.208124     Homo sapiens (human)   ESR1 Order cDNA clone, Links
Estrogen receptor 1 (ESR1)

Human protein-coding gene ESR1. Represented by 141 ESTs from 53 cDNA libraries. EST representation biased toward adult. Corresponds to 4 reference sequences (different isoforms). [UniGene 163517 - Hs.208124]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001116212.1 ESR1 gene product H. sapiens 100.0 594
XP_001097228.1 PREDICTED: estrogen receptor isoform 1 M. mulatta 99.7 594
XP_003311596.1 PREDICTED: estrogen receptor isoform 1 P. troglodytes 99.7 594
NP_001158059.1 estrogen receptor P. anubis 99.5 594
NP_031982.1 Esr1 gene product M. musculus 94.7 598
NP_001083084.2 estrogen receptor 1 X. laevis 81.9 584
NP_694491.1 esr1 gene product D. rerio 68.7 531
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_004011587.1 PREDICTED: estrogen receptor O. aries 96.4 446
XP_002714993.1 PREDICTED: estrogen receptor alpha-like O. cuniculus 96.0 597

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uterus; mammary gland; ovary; uncharacterized tissue; prostate; pancreas; muscle; testis; kidney; lung; pituitary gland; brain; spleen; trachea; thymus; heart; eye; connective tissue; adrenal gland; embryonic tissue; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q25.1
UniSTS entry: Chr 6 PMC108984P2
UniSTS entry: Chr 6 RH103609
UniSTS entry: BARC0078
UniSTS entry: Esr1
UniSTS entry: Esr1
UniSTS entry: Chr 6 D6S1846
UniSTS entry: Chr 6 RH46867 [Map Viewer]
UniSTS entry: Chr 1 D11S2766
UniSTS entry: Chr 1 D11S3014
UniSTS entry: Chr 4 D11S3026
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (86)

BX640939.1 Homo sapiens mRNA; cDNA DKFZp686N23123 (from clone DKFZp686N23123) PA
NM_000125.3 Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1, mRNA PA
M12674.1 Human estrogen receptor mRNA, complete cds P
AF120105.1 Homo sapiens alternatively-spliced estrogen receptor alpha mRNA, partial cds P
AY750962.1 Homo sapiens estrogen receptor alpha mamillary body 1 isoform mRNA, partial cds, alternatively spliced P
AF258449.1 Homo sapiens estrogen receptor alpha mRNA, complete cds, alternatively spliced P
AF258450.1 Homo sapiens estrogen receptor alpha mRNA, complete cds, alternatively spliced P
AF258451.1 Homo sapiens estrogen receptor alpha mRNA, complete cds, alternatively spliced P
DQ163909.1 Homo sapiens hippocampal estrogen receptor alpha isoform TADDI (ESR1) mRNA, partial cds, alternatively spliced
BC128574.1 Homo sapiens estrogen receptor 1, mRNA (cDNA clone MGC:157709 IMAGE:40128595), complete cds P
BC128573.1 Homo sapiens estrogen receptor 1, mRNA (cDNA clone MGC:157708 IMAGE:40128594), complete cds P
EF491789.1 Homo sapiens clone ESR1 mRNA, partial sequence; alternatively spliced
AK293019.1 Homo sapiens cDNA FLJ77952 complete cds, highly similar to Homo sapiens mRNA for oestrogen receptor P
AK313644.1 Homo sapiens cDNA, FLJ94220 P
AK311064.1 Homo sapiens cDNA, FLJ18106 P
AK309580.1 Homo sapiens cDNA, FLJ99621 P
NM_001122742.1 Homo sapiens estrogen receptor 1 (ESR1), transcript variant 4, mRNA PA
NM_001122741.1 Homo sapiens estrogen receptor 1 (ESR1), transcript variant 3, mRNA PA
NM_001122740.1 Homo sapiens estrogen receptor 1 (ESR1), transcript variant 2, mRNA PA
X03635.1 Homo sapiens mRNA for oestrogen receptor P
AK304833.1 Homo sapiens cDNA FLJ51616 complete cds, highly similar to Estrogen receptor P
AK304600.1 Homo sapiens cDNA FLJ51617 complete cds, highly similar to Estrogen receptor P
EU921455.1 Homo sapiens estrogen receptor alpha delta 3,4,5,6 isoform (ESR1) mRNA, partial cds, alternatively spliced P
EU982840.1 Homo sapiens estrogen receptor alpha cingulate gyrus isoform (ESR1) mRNA, partial cds, alternatively spliced P
EU982839.1 Homo sapiens estrogen receptor alpha superior frontal gyrus isoform (ESR1) mRNA, partial cds, alternatively spliced P
EU982838.1 Homo sapiens estrogen receptor alpha substantia nigra isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ147558.1 Homo sapiens caudal hypothalamus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced P
FJ147557.1 Homo sapiens rostral hypothalamus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced P
FJ147556.1 Homo sapiens choroid plexus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced P
FJ147555.1 Homo sapiens spinal cord estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced
FJ147554.1 Homo sapiens inferior temporal gyrus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced P
FJ147553.1 Homo sapiens middle hypothalamus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced P
FJ147552.1 Homo sapiens rostral hypothalamus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced P
FJ169504.1 Homo sapiens estrogen receptor alpha delta 4,5,6,7 isoform (ESR1) mRNA, partial cds, alternatively spliced
FJ169503.1 Homo sapiens estrogen receptor alpha delta 4*,5,6*/481 hypothalamic isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ169502.1 Homo sapiens estrogen receptor alpha delta 4,7*,8*/581 hypothalamic isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ169501.1 Homo sapiens estrogen receptor alpha delta 3*,4,5,6,7*/775 hypothalamic isoform (ESR1) mRNA, partial cds, alternatively spliced
FJ169500.1 Homo sapiens estrogen receptor alpha delta 2*,3,4,5,6,7*/834 hypothalamic isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ011560.1 Homo sapiens pituitary gland estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced
FJ011559.1 Homo sapiens locus coeruleus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced
FJ011558.1 Homo sapiens pineal gland estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced
FJ011557.1 Homo sapiens putamen estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced P
FJ011556.1 Homo sapiens caudal hypothalamus estrogen receptor alpha splice variant (ESR1) mRNA, partial cds, alternatively spliced
X73067.1 H. sapiens mRNA for estrogen receptor
U68068.1 Human estrogen receptor mRNA, alternatively spliced transcript H, partial cds
U68067.1 Human estrogen receptor mRNA, alternatively spliced transcript E, partial cds
X86816.1 H.sapiens estrogen receptor cDNA, 5' splice variant
Z75126.1 H.sapiens mRNA for estrogen receptor (hormone binding region) P
M69297.1 Human estrogen receptor-related protein (variant ER from breast cancer) mRNA, complete cds P
AB307713.1 Homo sapiens NR3A1 mRNA for estrogen receptor 1, complete cds P
FJ668387.1 Homo sapiens estrogen receptor alpha delta 4,5,7 isoform (ESR1) mRNA, partial cds, alternatively spliced
FJ712307.1 Homo sapiens estrogen receptor alpha delta 3*4*,7 isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ712306.1 Homo sapiens estrogen receptor alpha delta 3*4,5,6,7*/840 isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ712305.1 Homo sapiens estrogen receptor alpha delta 3*4,5*,7 isoform (ESR1) mRNA, partial cds, alternatively spliced
FJ716814.1 Homo sapiens estrogen receptor alpha delta 6,7 isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ716815.1 Homo sapiens estrogen receptor alpha delta 4*,5,6,7,8*/885 isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ716813.1 Homo sapiens estrogen receptor alpha delta 3*,4,5,6,7*, 8*/912 isoform (ESR1) mRNA, partial cds, alternatively spliced
FJ716812.1 Homo sapiens estrogen receptor alpha delta 4*,5,6,7*/633 isoform (ESR1) mRNA, partial cds, alternatively spliced P
FJ716811.1 Homo sapiens estrogen receptor alpha delta 4*,5,6,7,8*/918 isoform (ESR1) mRNA, partial cds, alternatively spliced P
GQ438793.1 Homo sapiens estrogen receptor alpha 3*,4,5,6,7,8*/984 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ438791.1 Homo sapiens estrogen receptor alpha delta 4*,5,6,7*/654 isoform (ESR1) mRNA, partial cds, alternatively spliced P
GQ438790.1 Homo sapiens estrogen receptor alpha 3*,4,5,6,7*/822 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ438789.1 Homo sapiens estrogen receptor alpha 3*,4,5,6,7,8*/1032 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ411258.1 Homo sapiens estrogen receptor alpha delta 4 +49 isoform (ESR1) mRNA, partial cds, alternatively spliced P
GQ411257.1 Homo sapiens estrogen receptor alpha delta 3*,4,5,6,7,8*/1029 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ411255.1 Homo sapiens estrogen receptor alpha delta 3*,4,5,6,7,8*/984 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ411254.1 Homo sapiens estrogen receptor alpha delta 3*,4,5,6,7,8*/969 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ411253.1 Homo sapiens estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform (ESR1) mRNA, partial cds, alternatively spliced P
GQ411251.1 Homo sapiens estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ411250.1 Homo sapiens estrogen receptor alpha delta 3*,4,5,6,7*/819-2 isoform (ESR1) mRNA, partial cds, alternatively spliced P
GQ411256.1 Homo sapiens estrogen receptor alpha delta 2*,3,4,5,6,7*/963 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ411252.1 Homo sapiens estrogen receptor alpha delta 2*,3,4,5,6,7 isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ389792.1 Homo sapiens estrogen receptor alpha 2*,3,4,5,6,7*,8* isoform (ESR1) mRNA, partial cds, alternatively spliced
GQ366704.1 Homo sapiens estrogen receptor alpha 3*,4,5,6,7*/765 isoform (ESR1) mRNA, partial cds, alternatively spliced
X74439.1 H.sapiens mRNA for estrogen receptor gene 5'flanking region
AB588630.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha, partial cds, novel splicing F isoform, F-E2-E3-2
AB588629.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha, partial cds, novel splicing F isoform, F-E2-E3-1-2 P
JF810888.1 Homo sapiens estrogen nuclear receptor alpha (ESR1) mRNA, complete cds P
AB685820.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha E1-N2-E2-2 variant, partial cds
AB685818.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha E1-2 variant, partial cds
AB685814.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha E1-1-2 variant, partial cds P
AB685819.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha E1-E2-2 variant, partial cds
AB685817.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha E1-N2-E2-1-2 variant, partial cds P
AB685815.1 Homo sapiens ESR1 mRNA for estrogen receptor alpha E1-E2-1-2 variant, partial cds P
U47678.1 Human 80 kDa estrogen receptor mRNA, containing exon 6 and 7 duplication, complete cds P
S80316.1 oestrogen receptor {alternatively spliced, exons 4 and 7} [human, endometrial liver, mRNA Partial Mutant, 144 nt]

EST sequences (10 of 141) [Show all sequences]

AI025006.1 Clone IMAGE:1631712 mammary gland 3' read
AI073549.1 Clone IMAGE:1640294 testis 3' read PA
AI127412.1 Clone IMAGE:1705898 heart 3' read P
BX108369.1 Clone IMAGp998C181779_;_IMAGE:725321 ovary A
AI202659.1 Clone IMAGE:1943657 prostate 3' read A
AI274727.1 Clone IMAGE:1986505 uterus 3' read A
AI273871.1 Clone IMAGE:1964251 ovary 3' read A
AI370308.1 Clone IMAGE:1987501 uterus 3' read A
CB215772.1 Clone IMAGE:5937582 uterus 5' read
AI524356.1 Clone IMAGE:2118591 prostate 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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