> Aprataxin (APTX)
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UGID:134046     UniGene Hs.20158     Homo sapiens (human)   APTX Order cDNA clone, Links
Aprataxin (APTX)

Human protein-coding gene APTX. Represented by 388 ESTs from 205 cDNA libraries. Corresponds to 12 reference sequences (different isoforms). [UniGene 134046 - Hs.20158]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001158355.1 PREDICTED: aprataxin isoform 17 P. troglodytes 100.0 355
NP_001182177.1 APTX gene product H. sapiens 100.0 355
XP_003911659.1 PREDICTED: aprataxin isoform 1 P. anubis 99.7 341
NP_001020615.1 aprataxin isoform b M. musculus 92.8 333
NP_001082689.1 aprataxin X. laevis 68.3 343
NP_999894.1 aptx gene product D. rerio 67.7 322
NP_195751.1 aprataxin A. thaliana 49.4 162
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_002800109.1 PREDICTED: aprataxin isoform 2 M. mulatta 98.9 355
XP_001917754.2 PREDICTED: aprataxin E. caballus 95.9 344

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mixed; lung; placenta; uncharacterized tissue; prostate; embryonic tissue; kidney; skin; lymph node; eye; blood; intestine; muscle; pharynx; pituitary gland; uterus; liver; mammary gland; cervix; connective tissue; bone marrow; heart; ovary; mouth; esophagus; spleen; trachea; thymus; thyroid; lymph; vascular; pancreas; stomach; salivary gland; bladder; ascites; nerve; bone; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9p13.3
UniSTS entry: Chr 9 RH46890 [Map Viewer]
UniSTS entry: Chr 9 G20636
UniSTS entry: Chr 9 A005Z44
UniSTS entry: AB056422
UniSTS entry: Chr 9 A009S13
UniSTS entry: Chr 9 RH16252
UniSTS entry: Chr 9 SHGC-34030 [Map Viewer]
UniSTS entry: Chr 9 G32803
UniSTS entry: Chr 1 RH80030
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (51)

NM_175073.2 Homo sapiens aprataxin (APTX), transcript variant 1, mRNA PA
NM_175069.2 Homo sapiens aprataxin (APTX), transcript variant 2, mRNA PA
AJ565855.1 Homo sapiens partial mRNA for aprataxin (APTX gene), splice variant 6 P
AJ565854.1 Homo sapiens partial mRNA for aprataxin (APTX gene), splice variant 5 P
AJ565853.1 Homo sapiens partial mRNA for aprataxin (APTX gene), splice variant 4 P
AJ565852.1 Homo sapiens partial mRNA for aprataxin (APTX gene), splice variant 3 P
AJ565851.1 Homo sapiens partial mRNA for aprataxin (APTX gene), splice variant 2 P
AJ565850.1 Homo sapiens partial mRNA for aprataxin (APTX gene), splice variant 1 P
BX538161.1 Homo sapiens mRNA; cDNA DKFZp686L1965 (from clone DKFZp686L1965); complete cds PA
AY040777.1 Homo sapiens forkhead-associated domain histidine-triad like protein mRNA, complete cds PA
AJ575566.1 Homo sapiens partial mRNA for aprataxin (APTX gene), splice variant 7 P
AK131046.1 Homo sapiens cDNA FLJ29012 fis, clone DMC08206 P
AY208842.1 Homo sapiens lymphoma FHA-HIT aberrant isoform mRNA, complete cds; alternatively spliced PA
AY208841.1 Homo sapiens retinoblastoma FHA-HIT aberrant isoform mRNA, complete cds; alternatively spliced PA
AY208840.1 Homo sapiens muscle FHA-HIT aberrant isoform mRNA, complete cds; alternatively spliced PA
AY208839.1 Homo sapiens melanotic melanoma FHA-HIT aberrant isoform mRNA, complete cds; alternatively spliced PA
AY208838.1 Homo sapiens lung small cell carcinoma FHA-HIT aberrant isoform mRNA, complete cds; alternatively spliced PA
AY208837.1 Homo sapiens lung small cell carcinoma FHA-HIT aberrant isoform mRNA, complete cds; alternatively spliced PA
AY208836.1 Homo sapiens lung small cell carcinoma FHA-HIT aberrant isoform mRNA, complete cds; alternatively spliced PA
AY208835.1 Homo sapiens hypothalamus FHA-HIT isoform mRNA, complete cds; alternatively spliced P
AY208834.1 Homo sapiens dendritic cells FHA-HIT isoform mRNA, complete cds; alternatively spliced P
AY208833.1 Homo sapiens kidney FHA-HIT isoform 2 mRNA, complete cds; alternatively spliced P
AY208832.1 Homo sapiens kidney FHA-HIT isoform 1 mRNA, complete cds; alternatively spliced P
AY208831.1 Homo sapiens skin FHA-HIT isoform mRNA, complete cds; alternatively spliced PA
AY208830.1 Homo sapiens testis FHA-HIT short isoform mRNA, complete cds; alternatively spliced PA
AY208829.1 Homo sapiens FHA-HIT short isoform mRNA, complete cds; alternatively spliced PA
BC068107.1 Homo sapiens aprataxin, mRNA (cDNA clone IMAGE:6384129) PA
AK000164.1 Homo sapiens cDNA FLJ20157 fis, clone COL08833 PA
AY302074.1 Homo sapiens aprataxin variant LP2P3E5 (APTX) mRNA, complete cds PA
AY302073.1 Homo sapiens aprataxin variant LP3E5 (APTX) mRNA, complete cds PA
AY302072.1 Homo sapiens aprataxin variant LP2E5 (APTX) mRNA, complete cds PA
AY302071.1 Homo sapiens aprataxin variant LE5 (APTX) mRNA, complete cds PA
AY302070.1 Homo sapiens aprataxin variant LP2P3 (APTX) mRNA, complete cds PA
AY302069.1 Homo sapiens aprataxin variant LP3 (APTX) mRNA, complete cds PA
AY302068.1 Homo sapiens aprataxin variant LP2 (APTX) mRNA, complete cds PA
AY302067.1 Homo sapiens aprataxin (APTX) mRNA, complete cds PA
BC104881.1 Homo sapiens aprataxin, transcript variant 1, mRNA (cDNA clone MGC:132541 IMAGE:8143884), complete cds P
BC001628.1 Homo sapiens aprataxin, mRNA (cDNA clone IMAGE:3538192), complete cds PA
AK055672.1 Homo sapiens cDNA FLJ31110 fis, clone IMR322000223, highly similar to Aprataxin (Forkhead-associated domain histidine triad-like protein) P
BC032650.1 Homo sapiens aprataxin, mRNA (cDNA clone MGC:45060 IMAGE:5505120), complete cds PA
NM_001195252.1 Homo sapiens aprataxin (APTX), transcript variant 11, mRNA P
NM_001195251.1 Homo sapiens aprataxin (APTX), transcript variant 9, mRNA P
NM_001195250.1 Homo sapiens aprataxin (APTX), transcript variant 8, mRNA P
NM_001195249.1 Homo sapiens aprataxin (APTX), transcript variant 7, mRNA P
NM_001195248.1 Homo sapiens aprataxin (APTX), transcript variant 6, mRNA P
NM_001195254.1 Homo sapiens aprataxin (APTX), transcript variant 10, mRNA P
AB603741.1 Homo sapiens APTX mRNA for aprataxin, partial cds PA
NR_036579.1 Homo sapiens aprataxin (APTX), transcript variant 15, non-coding RNA PA
NR_036577.1 Homo sapiens aprataxin (APTX), transcript variant 13, non-coding RNA PA
NR_036578.1 Homo sapiens aprataxin (APTX), transcript variant 14, non-coding RNA PA
NR_036576.1 Homo sapiens aprataxin (APTX), transcript variant 12, non-coding RNA PA

EST sequences (10 of 388) [Show all sequences]

AI001059.1 Clone IMAGE:1610283 mammary gland 3' read P
AA923481.1 Clone IMAGE:1534550 kidney 3' read A
AI004549.1 Clone IMAGE:1620352 testis 3' read PA
R17982.1 Clone IMAGE:32283 brain 5' read
AI032627.1 Clone IMAGE:1647124 parathyroid 3' read A
AI081440.1 Clone IMAGE:1680367 skin 3' read A
AI081442.1 Clone IMAGE:1680371 skin 3' read A
AI094708.1 Clone IMAGE:1670646 brain 3' read A
AI083586.1 Clone IMAGE:1660785 mixed 3' read A
AI139862.1 Clone IMAGE:1737435 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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