Minichromosome maintenance complex component 10 (MCM10)

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UGID:161818 UniGene Hs.198363 Homo sapiens (human) MCM10

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Minichromosome maintenance complex component 10 (MCM10)

Human protein-coding gene MCM10. Represented by 111 ESTs from 74 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 161818 - Hs.198363]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_877428.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MCM10 gene product	H. sapiens	100.0	874
XP_001140870.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein MCM10 homolog isoform 3	P. troglodytes	99.5	873
NP_081566.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Mcm10 gene product	M. musculus	83.7	884
NP_001082047.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	protein MCM10 homolog	X. laevis	69.7	858
NP_001019984.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	mcm10 gene product	D. rerio	61.0	830
Other hits (2 of 25) [Show all]		Species	Id(%)	Len(aa)
XP_003903445.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein MCM10 homolog	P. anubis	98.2	873
XP_001085751.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: protein MCM10 homolog	M. mulatta	96.7	864

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	embryonic tissue; vascular; uterus; bone marrow; brain; uncharacterized tissue; cervix; liver; mixed; mammary gland; kidney; lymph; bone; testis; thymus; salivary gland; eye; ascites; placenta; blood; skin; prostate; intestine; lymph node; heart; larynx

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	10
	Map position:	10p13

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_182751.2	Homo sapiens minichromosome maintenance complex component 10 (MCM10), transcript variant 1, mRNA	PA
NM_018518.4	Homo sapiens minichromosome maintenance complex component 10 (MCM10), transcript variant 2, mRNA	PA
BC101727.1	Homo sapiens minichromosome maintenance complex component 10, mRNA (cDNA clone MGC:126776 IMAGE:8069233), complete cds	P
AB042719.1	Homo sapiens mRNA for MCM10 homolog, complete cds	P
AL136840.1	Homo sapiens mRNA; cDNA DKFZp434H152 (from clone DKFZp434H152)	PA
BC004876.2	Homo sapiens minichromosome maintenance complex component 10, mRNA (cDNA clone IMAGE:3688557), partial cds	PA
BC009108.1	Homo sapiens cDNA clone IMAGE:3451214	PA
AK292701.1	Homo sapiens cDNA FLJ77264 complete cds, highly similar to Homo sapiens MCM10 minichromosome maintenance deficient 10 (MCM10), transcript variant 1, mRNA	P
AK055695.1	Homo sapiens cDNA FLJ31133 fis, clone IMR322000973, weakly similar to DNA43 PROTEIN	P
AF119869.1	Homo sapiens PRO2249 mRNA, complete cds	PA
BC143490.1	Homo sapiens minichromosome maintenance complex component 10, mRNA (cDNA clone MGC:177015 IMAGE:9051998), complete cds	P

EST sequences (10 of 111) [Show all sequences]

AI005288.1	Clone IMAGE:1625633	mixed	3' read	P
AI078425.1	Clone IMAGE:1674474	mixed	3' read	P
BX099770.1	Clone IMAGp998O073249_;_IMAGE:1290078	lymph node		P
CB143720.1	Clone L16HLK3-17-C05	liver	5' read	P
CB120985.1	Clone L8SCK0-41-H08	liver	5' read	P
AI636632.1	Clone IMAGE:2238704	uncharacterized tissue	3' read	P
AI750442.1	Clone NHTBC_cn03a01	bone
AI750443.1	Clone NHTBC_cn03a01	bone
BX346400.2	Clone CS0DL009YK18	uncharacterized tissue	5' read	P
BX324497.1	Clone CS0DC024YB02	uncharacterized tissue	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria