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UGID:131126     UniGene Hs.1976     Homo sapiens (human)   PDGFB Order cDNA clone, Links
Platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) (PDGFB)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_002599.1 platelet-derived growth factor beta isoform 1 preproprotein H. sapiens 100.0 240
XP_001097395.1 PREDICTED: platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) M. mulatta 99.6 240
XP_515140.2 PREDICTED: hypothetical protein P. troglodytes 99.6 240
XP_001473338.1 PREDICTED: similar to platelet-derived growth factor B chain M. musculus 90.5 240
NP_001087935.1 pdgfb protein X. laevis 56.4 211
NP_001070225.1 platelet derived growth factor alpha b D. rerio 49.1 218

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; uncharacterized tissue; embryonic tissue; testis; vascular; lung; mouth; mammary gland; intestine; mixed; blood; liver; kidney; ovary; pancreas
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q12.3-q13.1|22q13.1
UniSTS entry: Chr 22 D22S1108
UniSTS entry: Chr 22 (n/a)
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

NM_002608.2 Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) (PDGFB), transcript variant 1, mRNA PA
CR456538.1 Homo sapiens PDGFB full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.PDGFB.V2) P
CR541807.1 Homo sapiens full open reading frame cDNA clone RZPDo834G0631D for gene PDGFB, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); complete cds, incl. stopcodon P
CR620580.1 full-length cDNA clone CS0DI008YH01 of Placenta Cot 25-normalized of Homo sapiens (human)
CR601724.1 full-length cDNA clone CS0DF009YD01 of Fetal brain of Homo sapiens (human) P
BC077725.1 Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), mRNA (cDNA clone MGC:78575 IMAGE:6379783), complete cds PA
AK022920.1 Homo sapiens cDNA FLJ12858 fis, clone NT2RP2003517, highly similar to Human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) mRNA
M12783.1 Human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) mRNA, complete cds P
NM_033016.2 Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) (PDGFB), transcript variant 2, mRNA PA
X02811.1 Human mRNA for platelet-derived growth factor B chain (PDGF-B) P
X03702.1 Human osteosarcoma cell line U-2 OS mRNA fragment for PDGF-B chain (PDGF= platelet-derived growth factor) P
BC029822.1 Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), mRNA (cDNA clone MGC:34575 IMAGE:5174750), complete cds PA
X02744.1 Human mRNA for c-sis gene (clone pSM-1) P
X83705.1 H.sapiens mRNA for c-sis proto-oncogene P
M32009.1 Human c-sis oncogene mRNA, 3' flank

EST sequences (10 of 71) [Show all sequences]

R14265.1 Clone IMAGE:28332 brain 5' read
AI286212.1 Clone IMAGE:1855307 mixed 3' read A
AI393607.1 Clone IMAGE:2111862 mixed 3' read
R40559.1 Clone IMAGE:28332 brain 3' read A
AI688261.1 Clone IMAGE:2326245 intestine 3' read A
BX280801.1 Clone IMAGp998F154726_;_IMAGE:1926542 intestine
AI924340.1 Clone IMAGE:2449383 lung 3' read
CB960288.1 Clone IMAGE:30343336 placenta 5' read
BX377588.2 Clone CS0DI008YH01 placenta 3' read A
BX377589.2 Clone CS0DI008YH01 placenta 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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