> Platelet-derived growth factor beta polypeptide (PDGFB)
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UGID:131126     UniGene Hs.1976     Homo sapiens (human)   PDGFB Order cDNA clone, Links
Platelet-derived growth factor beta polypeptide (PDGFB)

Human protein-coding gene PDGFB. Represented by 117 ESTs from 70 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 131126 - Hs.1976]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002599.1 PDGFB gene product H. sapiens 100.0 240
XP_001097395.1 PREDICTED: platelet-derived growth factor subunit B M. mulatta 99.6 240
XP_003905609.1 PREDICTED: platelet-derived growth factor subunit B P. anubis 99.6 240
XP_515140.2 PREDICTED: platelet-derived growth factor subunit B isoform 2 P. troglodytes 99.6 240
NP_035187.2 Pdgfb gene product M. musculus 90.9 240
NP_001081304.1 platelet-derived growth factor subunit A precursor X. laevis 46.9 179
Other hits (2 of 14) [Show all]SpeciesId(%)Len(aa)
NP_001003383.1 PDGFB gene product C. lupus familiaris 94.2 241
NP_001009471.1 PDGFB gene product O. aries 92.5 240

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; brain; uncharacterized tissue; intestine; mouth; mammary gland; mixed; lung; testis; pancreas; vascular; ovary; blood; liver; kidney; heart; embryonic tissue; uterus; epididymis; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q13.1
UniSTS entry: Chr 22 D22S1108 [Map Viewer]
UniSTS entry: Chr 22 PDGFB_1020
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_002608.2 Homo sapiens platelet-derived growth factor beta polypeptide (PDGFB), transcript variant 1, mRNA PA
CR456538.1 Homo sapiens PDGFB full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.PDGFB.V2) P
CR541807.1 Homo sapiens full open reading frame cDNA clone RZPDo834G0631D for gene PDGFB, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); complete cds, incl. stopcodon P
BC077725.1 Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), mRNA (cDNA clone MGC:78575 IMAGE:6379783), complete cds PA
AK022920.1 Homo sapiens cDNA FLJ12858 fis, clone NT2RP2003517, highly similar to Human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) mRNA
M12783.1 Human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) mRNA, complete cds P
NM_033016.2 Homo sapiens platelet-derived growth factor beta polypeptide (PDGFB), transcript variant 2, mRNA PA
X02811.1 Human mRNA for platelet-derived growth factor B chain (PDGF-B) P
X03702.1 Human osteosarcoma cell line U-2 OS mRNA fragment for PDGF-B chain (PDGF= platelet-derived growth factor) P
BC029822.1 Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), mRNA (cDNA clone MGC:34575 IMAGE:5174750), complete cds PA
X02744.1 Human mRNA for c-sis gene (clone pSM-1) P
X83705.1 H.sapiens mRNA for c-sis proto-oncogene P
M32009.1 Human c-sis oncogene mRNA, 3' flank

EST sequences (10 of 117) [Show all sequences]

R14265.1 Clone IMAGE:28332 brain 5' read
AI002844.1 Clone IMAGE:1698699 kidney 3' read
AA947584.1 Clone IMAGE:1508454 mixed 3' read
AI273255.1 Clone IMAGE:1875279 intestine 3' read A
AI286212.1 Clone IMAGE:1855307 mixed 3' read A
AI304555.1 Clone IMAGE:1912434 intestine 3' read
AI393607.1 Clone IMAGE:2111862 mixed 3' read
AI524772.1 Clone IMAGE:2181176 uterus 3' read
R40559.1 Clone IMAGE:28332 brain 3' read A
AI635801.1 Clone IMAGE:2294961 pancreas 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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