> NIMA-related kinase 6 (NEK6)
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UGID:161657     UniGene Hs.197071     Homo sapiens (human)   NEK6 Order cDNA clone, Links
NIMA-related kinase 6 (NEK6)

Human protein-coding gene NEK6. Represented by 375 ESTs from 179 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 161657 - Hs.197071]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003312322.1 PREDICTED: serine/threonine-protein kinase Nek6 isoform 4 P. troglodytes 100.0 346
NP_001138473.1 serine/threonine-protein kinase Nek6 isoform 1 H. sapiens 100.0 346
NP_067619.1 serine/threonine-protein kinase Nek6 M. musculus 99.4 312
NP_001080654.1 NIMA-related kinase 6 X. laevis 94.8 306
NP_001003617.1 nek7 gene product D. rerio 91.9 283
NP_510080.2 Protein NEKL-3 C. elegans 81.2 276
XP_001690772.1 NimA-related protein kinase 7 C. reinhardtii 57.0 284
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_003911297.1 PREDICTED: serine/threonine-protein kinase Nek6 isoform 3 P. anubis 99.4 357
NP_891998.1 Nek6 gene product R. norvegicus 99.4 312

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uncharacterized tissue; placenta; lung; kidney; thyroid; vascular; muscle; skin; spleen; trachea; amniotic fluid; prostate; spinal cord; stomach; ovary; tonsil; ascites; testis; uterus; lymph; bone; embryonic tissue; liver; intestine; eye; blood; lymph node; pancreas; pharynx; mammary gland; mouth; connective tissue; cervix; heart; umbilical cord; adipose tissue; bone marrow; salivary gland; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q33.3-q34.11
UniSTS entry: Chr 9 SGC33089 [Map Viewer]
UniSTS entry: Chr 9 RH12239
UniSTS entry: Chr 9 RH11482 [Map Viewer]
UniSTS entry: Chr 9 RH11599
UniSTS entry: Chr 9 G20648
UniSTS entry: Chr 9 A006A17
UniSTS entry: Chr 9 RH77983
UniSTS entry: Chr 9 RH70504 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

AB026289.1 Homo sapiens mRNA for protein kinase SID6-1512, complete cds PA
CR457091.1 Homo sapiens full open reading frame cDNA clone RZPDo834E1011D for gene NEK6, NIMA (never in mitosis gene a)-related kinase 6; complete cds, incl. stopcodon P
CR542222.1 Homo sapiens full open reading frame cDNA clone RZPDo834C0925D for gene NEK6, NIMA (never in mitosis gene a)-related kinase 6; complete cds, without stopcodon P
NM_014397.5 Homo sapiens NIMA-related kinase 6 (NEK6), transcript variant 2, mRNA PA
AY567967.1 Homo sapiens myeloproliferative disease associated tumor antigen-5 mRNA, complete cds
AF087909.1 Homo sapiens NIMA-related kinase 6 (NEK6) mRNA, complete cds P
BC000101.2 Homo sapiens NIMA (never in mitosis gene a)-related kinase 6, mRNA (cDNA clone MGC:1205 IMAGE:3507262), complete cds PA
BC004209.2 Homo sapiens NIMA (never in mitosis gene a)-related kinase 6, mRNA (cDNA clone MGC:4434 IMAGE:2958695), complete cds PA
BC004174.2 Homo sapiens NIMA (never in mitosis gene a)-related kinase 6, mRNA (cDNA clone MGC:2768 IMAGE:2958695), complete cds PA
BC012761.2 Homo sapiens NIMA (never in mitosis gene a)-related kinase 6, mRNA (cDNA clone MGC:16199 IMAGE:3640103), complete cds PA
AK313071.1 Homo sapiens cDNA, FLJ93552, Homo sapiens NIMA (never in mitosis gene a)-related kinase 6 (NEK6), mRNA P
AL832574.2 Homo sapiens mRNA; cDNA DKFZp451D1716 (from clone DKFZp451D1716) A
AJ420460.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1636598 A
AK294614.1 Homo sapiens cDNA FLJ55200 complete cds, highly similar to Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) P
NM_001145001.2 Homo sapiens NIMA-related kinase 6 (NEK6), transcript variant 1, mRNA PA
NM_001166171.1 Homo sapiens NIMA-related kinase 6 (NEK6), transcript variant 7, mRNA PA
NM_001166170.1 Homo sapiens NIMA-related kinase 6 (NEK6), transcript variant 6, mRNA PA
NM_001166169.1 Homo sapiens NIMA-related kinase 6 (NEK6), transcript variant 4, mRNA PA
NM_001166168.1 Homo sapiens NIMA-related kinase 6 (NEK6), transcript variant 5, mRNA PA
NM_001166167.1 Homo sapiens NIMA-related kinase 6 (NEK6), transcript variant 3, mRNA PA

EST sequences (10 of 375) [Show all sequences]

R14353.1 Clone IMAGE:28558 brain 5' read
AA969269.1 Clone IMAGE:1560796 mixed 3' read
AA992937.1 Clone IMAGE:1624985 embryonic tissue 3' read
AI000186.1 Clone IMAGE:1636598 kidney 3' read
AA906804.1 Clone IMAGE:1519567 uncharacterized tissue 3' read A
AI073411.1 Clone IMAGE:1640347 testis 3' read A
AI080636.1 Clone IMAGE:1660132 embryonic tissue 3' read A
AI091790.1 Clone IMAGE:1694143 heart 3' read
AI094031.1 Clone IMAGE:1688083 mixed 3' read P
AI095604.1 Clone IMAGE:1697181 uterus 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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