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UGID:161544     UniGene Hs.196384     Homo sapiens (human)   PTGS2 Order cDNA clone, Links
Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_000954.1 prostaglandin-endoperoxide synthase 2 precursor H. sapiens 100.0 603
XP_524999.2 PREDICTED: prostaglandin-endoperoxide synthase 2 P. troglodytes 99.8 652
NP_035328.2 prostaglandin-endoperoxide synthase 2 M. musculus 88.6 603
NP_001020675.1 prostaglandin-endoperoxide synthase 2b D. rerio 78.3 598
NP_001086946.1 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) X. laevis 77.7 600

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; vascular; cervix; prostate; uterus; uncharacterized tissue; pharynx; brain; lung; placenta; mixed; kidney; pancreas; stomach; mammary gland; skin; connective tissue; bone; embryonic tissue; eye; spleen; esophagus; trachea; larynx; muscle; bone marrow; nerve; intestine; liver; thyroid; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q25.2-q25.3
UniSTS entry: Chr 1 SHGC-76038
UniSTS entry: Chr 1 G65470
UniSTS entry: Chr 1 GDB:455285
UniSTS entry: Chr 1 (n/a)
UniSTS entry: Chr 1 G65466
UniSTS entry: Chr 1 G65467
UniSTS entry: Chr 1 G65468
UniSTS entry: Chr 1 G65469
UniSTS entry: Chr 1 G65465
UniSTS entry: Chr 1 G63790
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_000963.2 Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), mRNA PA
AY462100.1 Homo sapiens cyclooxygenase 2 (COX2) mRNA, complete cds P
AJ634912.1 Homo sapiens mRNA for putative cyclooxygenase-2 (COX-2 gene), splice variant COX-2a P
M90100.1 Homo sapiens cyclooxygenase-2 (Cox-2) mRNA, complete cds PA
BC013734.1 Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), mRNA (cDNA clone MGC:9576 IMAGE:3880850), complete cds PA
AK292167.1 Homo sapiens cDNA FLJ75306 complete cds, highly similar to Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), mRNA P
AY151286.1 Homo sapiens cyclooxygenase 2b mRNA, complete cds; alternatively spliced PA
L15326.1 Human endoperoxide synthase type II mRNA, complete cds P

EST sequences (10 of 162) [Show all sequences]

AI022012.1 Clone IMAGE:1651583 skin 3' read P
AI123006.1 Clone IMAGE:1509904 mixed 3' read A
BX115842.1 Clone IMAGp998E03223_;_IMAGE:147050 placenta A
CB146285.1 Clone L16HLK3-20-H12 liver 5' read P
CB143773.1 Clone L16HLK3-17-H10 liver 5' read P
AI401793.1 Clone IMAGE:2119661 prostate 3' read
AI610346.1 Clone IMAGE:2188171 stomach 3' read
AI610431.1 Clone IMAGE:2188151 stomach 3' read A
AI669722.1 Clone IMAGE:2314993 prostate 3' read A
CB243167.1 Clone UI-CF-FN0-agc-c-16-0-UI lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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