> V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC)
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UGID:161422     UniGene Hs.195659     Homo sapiens (human)   SRC Order cDNA clone, Links
V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC)

Human protein-coding gene SRC. Represented by 180 ESTs from 95 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 161422 - Hs.195659]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001092180.1 PREDICTED: proto-oncogene tyrosine-protein kinase Src isoform 1 M. mulatta 100.0 535
XP_003904820.1 PREDICTED: proto-oncogene tyrosine-protein kinase Src isoform 1 P. anubis 100.0 535
XP_001141228.2 PREDICTED: proto-oncogene tyrosine-protein kinase Src isoform 6 P. troglodytes 100.0 535
NP_938033.1 SRC gene product H. sapiens 100.0 535
XP_865870.1 PREDICTED: proto-oncogene tyrosine-protein kinase Src isoform 5 C. lupus familiaris 99.8 535
NP_001020566.1 Src gene product M. musculus 99.8 534
NP_001079114.1 tyrosine-protein kinase Src-1 X. laevis 95.3 531
NP_001003837.2 src gene product D. rerio 92.0 533
NP_476849.1 Src oncogene at 42A, isoform A D. melanogaster 64.6 469
NP_493502.1 Protein SRC-2 C. elegans 58.4 500
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
NP_114183.1 Src gene product R. norvegicus 99.5 541
XP_001928649.1 PREDICTED: proto-oncogene tyrosine-protein kinase Src S. scrofa 99.5 541

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; testis; brain; uncharacterized tissue; thyroid; liver; mouth; placenta; intestine; uterus; stomach; bone; larynx; trachea; prostate; skin; eye; embryonic tissue; pancreas; muscle; mixed; bladder; kidney; ovary; umbilical cord; blood; ascites; adrenal gland; lymph node; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q12-q13
UniSTS entry: Chr 20 RH98828
UniSTS entry: Chr 2 WI-14593 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BC051270.1 Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), mRNA (cDNA clone MGC:59921 IMAGE:4871614), complete cds PA
NM_005417.3 Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 1, mRNA PA
NM_198291.1 Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 2, mRNA PA
AK024281.1 Homo sapiens cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to Rattus norvegicus tyrosine protein kinase pp60-c-src mRNA P
BC011566.1 Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), mRNA (cDNA clone MGC:20184 IMAGE:4548399), complete cds PA
AF272982.1 Homo sapiens SRC tyrosine kinase mRNA, partial sequence, alternatively spliced
Z18364.1 H.sapiens 5' non-coding end of the c-Src proto-oncogene

EST sequences (10 of 180) [Show all sequences]

AA999869.1 Clone IMAGE:1636402 kidney 3' read A
AI055824.1 Clone IMAGE:1750215 brain 3' read A
AI083955.1 Clone IMAGE:1679035 skin 3' read A
AI084750.1 Clone IMAGE:1681588 skin 3' read A
AI219010.1 Clone IMAGE:1759236 placenta 3' read
AI198134.1 Clone IMAGE:1859988 brain 3' read A
AI273992.1 Clone IMAGE:1978761 stomach 3' read A
AI282193.1 Clone IMAGE:1927839 lung 3' read
AA724037.1 Clone IMAGE:1326187 mixed 3' read P
AI380629.1 Clone IMAGE:2107602 uncharacterized tissue 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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