Serum amyloid A4, constitutive (SAA4)

Restricted Expression:

liver [show more like this]

liver tumor [show more like this]

adult [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

liver; mixed; kidney; pharynx; lung

NCBI

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Finding cDNAs

UGID:131119 UniGene Hs.1955 Homo sapiens (human) SAA4

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Serum amyloid A4, constitutive (SAA4)

Human protein-coding gene SAA4. Represented by 45 ESTs from 13 cDNA libraries. EST representation biased toward liver; liver tumor; adult. Corresponds to reference sequence NM_006512.3. [UniGene 131119 - Hs.1955]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_001173012.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: serum amyloid A-4 protein isoform 2	P. troglodytes	100.0	129
NP_006503.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	SAA4 gene product	H. sapiens	100.0	129
NP_035446.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Saa4 gene product	M. musculus	58.5	129
Other hits (2 of 9) [Show all]		Species	Id(%)	Len(aa)
XP_001086019.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: serum amyloid A-4 protein isoform 2	M. mulatta	85.9	128
XP_003910205.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: serum amyloid A-4 protein	P. anubis	85.7	133

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11p15.1-p14
UniSTS entry:	Chr 11	STS-M81349
UniSTS entry:	Chr 11	STS-N22938

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

CR541758.1	Homo sapiens full open reading frame cDNA clone RZPDo834F1229D for gene SAA4, serum amyloid A4, constitutive; complete cds, without stopcodon	P
NM_006512.3	Homo sapiens serum amyloid A4, constitutive (SAA4), mRNA	PA
M81349.1	H.sapiens serum amyloid A protein mRNA, complete cds	P
BC007026.1	Homo sapiens serum amyloid A4, constitutive, mRNA (cDNA clone MGC:12381 IMAGE:4071711), complete cds	PA
AK312182.1	Homo sapiens cDNA, FLJ92469, highly similar to Homo sapiens serum amyloid A4, constitutive (SAA4), mRNA	P

EST sequences (10 of 45) [Show all sequences]

CB164120.1	Clone L17N670205n1-36-B07	liver	5' read	P
CB164427.1	Clone L17N670205n1-47-F12	liver	5' read
CB113387.1	Clone L7N800102-1-H06	liver	5' read	P
CB117022.1	Clone L7N800102-5-B08	liver	5' read	P
AI344545.1	Clone IMAGE:1917449	kidney	3' read	PA
AI379230.1	Clone IMAGE:2069318	mixed	3' read	A
CV027269.1		mixed	5' read	P
AV645410.2	Clone GLCAAA05	liver	3' read	P
AV645450.1	Clone GLCAAD09	liver	3' read	P
AV645558.1	Clone GLCABF01	liver	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria