> SIX homeobox 6 (SIX6)
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UGID:161273     UniGene Hs.194756     Homo sapiens (human)   SIX6 Order cDNA clone, Links
SIX homeobox 6 (SIX6)

Human protein-coding gene SIX6. Represented by 36 ESTs from 12 cDNA libraries. EST representation biased toward leukemia; juvenile. Corresponds to reference sequence NM_007374.2. [UniGene 161273 - Hs.194756]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_522870.3 PREDICTED: homeobox protein SIX6 P. troglodytes 100.0 245
NP_031400.2 SIX6 gene product H. sapiens 100.0 245
XP_003901939.1 PREDICTED: homeobox protein SIX6 P. anubis 99.6 245
XP_547840.3 PREDICTED: homeobox protein SIX6 C. lupus familiaris 99.6 245
NP_001155330.1 SIX6 gene product O. aries 99.6 245
XP_002719589.1 PREDICTED: SIX homeobox 3 O. cuniculus 99.6 245
NP_035514.1 Six6 gene product M. musculus 99.2 245
NP_001081933.1 SIX homeobox 6 X. laevis 95.9 243
NP_001018421.1 six6b gene product D. rerio 93.9 244
NP_524695.2 optix, isoform A D. melanogaster 75.5 310
NP_504420.1 Protein CEH-33 C. elegans 52.2 178
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
NP_001101502.1 Six6 gene product R. norvegicus 99.2 245
XP_001369291.1 PREDICTED: homeobox protein SIX6-like M. domestica 97.6 245

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: leukemia [show more like this]
juvenile [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; eye; pituitary gland; mixed
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q23.1
UniSTS entry: Six6
UniSTS entry: Chr 14 RH106539
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AJ011785.1 Homo sapiens mRNA for Six9 protein P
NM_007374.2 Homo sapiens SIX homeobox 6 (SIX6), mRNA PA
BC065831.1 Homo sapiens SIX homeobox 6, mRNA (cDNA clone IMAGE:30366326), partial cds PA
BC069413.1 Homo sapiens SIX homeobox 6, mRNA (cDNA clone MGC:97064 IMAGE:7262276), complete cds P
BC087852.1 Homo sapiens SIX homeobox 6, mRNA (cDNA clone IMAGE:30368943), partial cds PA

EST sequences (10 of 36) [Show all sequences]

AI332673.1 Clone IMAGE:1934347 mixed 3' read
CD107824.1 Clone IMAGE:30368943 pituitary gland 5' read P
CD107910.1 Clone IMAGE:30366326 pituitary gland 5' read P
BX326375.2 Clone CS0DJ009YA24 blood 5' read
BX341306.1 Clone CS0DJ014YN13 blood 3' read P
BX340899.2 Clone CS0DJ009YA24 blood 5' read P
BX341307.2 Clone CS0DJ014YN13 blood 5' read P
BX347421.2 Clone CS0DJ014YN13 blood 5' read
BX366211.2 Clone CS0DJ009YA24 blood 5' read P
BX347023.2 Clone CS0DJ009YA24 blood 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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