> MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2)
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UGID:133952     UniGene Hs.19400     Homo sapiens (human)   MAD2L2 Order cDNA clone, Links
MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2)

Human protein-coding gene MAD2L2. Represented by 247 ESTs from 123 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 133952 - Hs.19400]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001104002.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B isoform 1 M. mulatta 100.0 210
XP_003891160.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B isoform 1 P. anubis 100.0 210
XP_001138745.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B isoform 4 P. troglodytes 100.0 210
NP_006332.3 MAD2L2 gene product H. sapiens 100.0 210
XP_001492215.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B-like E. caballus 100.0 210
XP_003127615.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B-like S. scrofa 100.0 210
XP_004013768.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B O. aries 100.0 210
XP_544568.3 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B C. lupus familiaris 100.0 177
NP_001039411.1 MAD2L2 gene product B. taurus 99.5 210
XP_002724429.1 PREDICTED: MAD2 homolog O. cuniculus 99.5 210
NP_082261.2 Mad2l2 gene product M. musculus 99.0 210
NP_001081096.1 mitotic spindle assembly checkpoint protein MAD2B X. laevis 95.3 210
NP_001017595.1 si:dkey-23c22.2 gene product D. rerio 87.2 210
Other hits (2 of 14) [Show all]SpeciesId(%)Len(aa)
XP_001364117.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD2B-like M. domestica 99.0 210
NP_001232788.1 LOC100226442 gene product T. guttata 97.6 210

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; brain; uncharacterized tissue; lymph node; lymph; mixed; skin; ovary; kidney; eye; salivary gland; bone; muscle; stomach; lung; prostate; heart; umbilical cord; testis; pancreas; adipose tissue; blood; mammary gland; uterus; intestine; placenta; liver; bone marrow; connective tissue; ascites; nerve; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p36
UniSTS entry: Chr 1 RH80622
UniSTS entry: Chr 1 D1S1742E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_006341.3 Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 2, mRNA PA
AF139365.1 Homo sapiens Mad2B protein (MAD2B) mRNA, complete cds PA
AF072933.1 Homo sapiens Mad2-like protein mRNA, complete cds PA
AF080398.1 Homo sapiens MAD2-like protein mRNA, complete cds P
AF157482.1 Homo sapiens Rev7p (REV7) mRNA, complete cds PA
AK027327.1 Homo sapiens cDNA FLJ14421 fis, clone HEMBA1005621, highly similar to Mitotic spindle assembly checkpoint protein MAD2B P
BC015244.1 Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast), mRNA (cDNA clone MGC:17940 IMAGE:3916742), complete cds PA
NM_001127325.1 Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 1, mRNA PA
AK094316.1 Homo sapiens cDNA FLJ36997 fis, clone BRACE2007087, highly similar to Mitotic spindle assembly checkpoint protein MAD2B P

EST sequences (10 of 247) [Show all sequences]

AA974194.1 Clone IMAGE:1586277 uncharacterized tissue 3' read A
AA993790.1 Clone IMAGE:1622817 embryonic tissue 3' read A
AI085220.1 Clone IMAGE:1666001 skin 3' read A
AI146448.1 Clone IMAGE:1707636 heart 3' read A
CB054836.1 Clone IMAGE:3291727 brain 5' read A
AI185138.1 Clone IMAGE:1740522 lung 3' read A
AI219673.1 Clone IMAGE:1841193 mixed 3' read A
AI202349.1 Clone IMAGE:1943062 prostate 3' read A
CB106803.1 Clone L3SNU475-11-A06 liver 5' read P
CB117704.1 Clone B1T694954-3-D03 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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