> Uracil-DNA glycosylase (UNG)
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UGID:160615     UniGene Hs.191334     Homo sapiens (human)   UNG Order cDNA clone, Links
Uracil-DNA glycosylase (UNG)

Human protein-coding gene UNG. Represented by 559 ESTs from 237 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 160615 - Hs.191334]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001233452.1 UNG gene product P. troglodytes 100.0 312
NP_550433.1 UNG gene product H. sapiens 100.0 312
NP_001035781.1 uracil-DNA glycosylase isoform a M. musculus 92.2 305
NP_001085412.1 uracil-DNA glycosylase X. laevis 82.2 303
NP_957268.1 unga gene product D. rerio 81.4 290
XP_001703582.1 uracil DNA-glycosylase C. reinhardtii 61.3 186
NP_188493.1 uracil dna glycosylase A. thaliana 60.3 219
NP_001255148.1 Protein UNG-1, isoform d C. elegans 59.1 219
NP_013691.1 Ung1p S. cerevisiae 56.3 263
XP_965029.1 uracil-DNA glycosylase N. crassa 53.2 220
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_003907171.1 PREDICTED: uracil-DNA glycosylase isoform 1 P. anubis 99.4 312
XP_001104341.1 PREDICTED: uracil-DNA glycosylase isoform 1 M. mulatta 99.0 312

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; uncharacterized tissue; embryonic tissue; intestine; mixed; kidney; blood; testis; prostate; larynx; adrenal gland; pharynx; uterus; mammary gland; thyroid; skin; eye; lung; lymph; vascular; pancreas; stomach; cervix; lymph node; muscle; liver; ovary; connective tissue; heart; spleen; thymus; ascites; bladder; mouth; salivary gland; pituitary gland; nerve; bone marrow; umbilical cord; bone; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q23-q24.1
UniSTS entry: Chr 12 RH15692
UniSTS entry: Chr 12 WI-19583 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC050634.2 Homo sapiens uracil-DNA glycosylase, mRNA (cDNA clone MGC:60117 IMAGE:6500377), complete cds PA
NM_003362.3 Homo sapiens uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
CR541673.1 Homo sapiens full open reading frame cDNA clone RZPDo834D0128D for gene UNG, uracil-DNA glycosylase; complete cds, incl. stopcodon P
CR749342.1 Homo sapiens mRNA; cDNA DKFZp781L1143 (from clone DKFZp781L1143) PA
X15653.1 Human cDNA for uracil-DNA glycosylase PA
BC015205.1 Homo sapiens uracil-DNA glycosylase, mRNA (cDNA clone MGC:17032 IMAGE:3913667), complete cds PA
AK291341.1 Homo sapiens cDNA FLJ76845 complete cds, highly similar to Homo sapiens uracil-DNA glycosylase (UNG), transcript variant 1, mRNA P
AK313552.1 Homo sapiens cDNA, FLJ94113, Homo sapiens uracil-DNA glycosylase (UNG), nuclear gene encodingmitochondrial protein, transcript variant 2, mRNA P
NM_080911.2 Homo sapiens uracil-DNA glycosylase (UNG), transcript variant 2, mRNA PA
AK299416.1 Homo sapiens cDNA FLJ54140 complete cds, highly similar to Uracil-DNA glycosylase (EC 3.2.2.-) P
Y09008.1 H.sapiens mRNA for uracil-DNA glycosylase PA

EST sequences (10 of 559) [Show all sequences]

AA995682.1 Clone IMAGE:1606382 kidney 3' read A
AI089975.1 Clone IMAGE:1687363 brain 3' read A
AI095623.1 Clone IMAGE:1697203 uterus 3' read A
AI127421.1 Clone IMAGE:1705916 heart 3' read A
AI140058.1 Clone IMAGE:1693717 heart 3' read A
AI147623.1 Clone IMAGE:1696977 uterus 3' read A
BX098770.1 Clone IMAGp998J24653_;_IMAGE:293111 mixed
R25268.1 Clone IMAGE:36459 brain 5' read P
CB159969.1 Clone L18POOL1n1-45-B12 liver 5' read
CB160109.1 Clone L18POOL1n1-47-G12 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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