NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
Finding cDNAs

UGID:160129     UniGene Hs.188591     Homo sapiens (human)   TMEM135
Transmembrane protein 135 (TMEM135)

Human protein-coding gene TMEM135. Represented by 227 ESTs from 108 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 160129 - Hs.188591]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001175336.1 PREDICTED: transmembrane protein 135 isoform 4 P. troglodytes 100.0 457
NP_075069.3 TMEM135 gene product H. sapiens 100.0 457
XP_001104105.1 PREDICTED: transmembrane protein 135 M. mulatta 99.8 457
XP_003910568.1 PREDICTED: transmembrane protein 135-like P. anubis 99.7 318
NP_082619.3 Tmem135 gene product M. musculus 95.6 457
NP_001085541.1 transmembrane protein 135 X. laevis 87.9 452
NP_001082887.1 tmem135 gene product D. rerio 83.4 453
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_002708692.1 PREDICTED: transmembrane protein 135 isoform 1 O. cuniculus 98.2 457
XP_003365410.1 PREDICTED: transmembrane protein 135 isoform 2 E. caballus 98.2 456

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: vascular; brain; testis; lung; intestine; bone marrow; pituitary gland; embryonic tissue; liver; placenta; mixed; uncharacterized tissue; mouth; kidney; eye; uterus; muscle; mammary gland; adrenal gland; cervix; heart; prostate; skin; trachea; thymus; salivary gland; pancreas; parathyroid; blood; lymph node; lymph; connective tissue; ovary; stomach; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q14.2
UniSTS entry: Chr 11 RH94063
UniSTS entry: Chr 11 D11S4582
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BC051462.1 Homo sapiens transmembrane protein 135, mRNA (cDNA clone MGC:57140 IMAGE:5278478), complete cds PA
BX648678.1 Homo sapiens mRNA; cDNA DKFZp686I1974 (from clone DKFZp686I1974) PA
AK000684.1 Homo sapiens cDNA FLJ20677 fis, clone KAIA4183 PA
AK024853.1 Homo sapiens cDNA: FLJ21200 fis, clone COL00269 A
AK025757.1 Homo sapiens cDNA: FLJ22104 fis, clone HEP17633 PA
NM_022918.3 Homo sapiens transmembrane protein 135 (TMEM135), transcript variant 1, mRNA PA
AK225364.1 Homo sapiens mRNA for Hypothetical protein DKFZp686I1974 variant, clone: HEP17633 P
AK291804.1 Homo sapiens cDNA FLJ77427 complete cds P
BC030952.1 Homo sapiens transmembrane protein 135, mRNA (cDNA clone IMAGE:4097312), complete cds PA
AL834493.1 Homo sapiens mRNA; cDNA DKFZp434P0631 (from clone DKFZp434P0631) PA
AK296774.1 Homo sapiens cDNA FLJ55090 complete cds P
AK302473.1 Homo sapiens cDNA FLJ60967 complete cds P
BC012553.1 Homo sapiens transmembrane protein 135, mRNA (cDNA clone IMAGE:4282583), complete cds PA
NM_001168724.1 Homo sapiens transmembrane protein 135 (TMEM135), transcript variant 2, mRNA PA
NR_033149.1 Homo sapiens transmembrane protein 135 (TMEM135), transcript variant 3, non-coding RNA PA

EST sequences (10 of 227) [Show all sequences]

AA977408.1 Clone IMAGE:1590603 kidney 3' read A
AI016734.1 Clone IMAGE:1638508 testis 3' read
AI129652.1 Clone IMAGE:1712940 uterus 3' read
BX093273.1 Clone IMAGp998A16729_;_IMAGE:322071 parathyroid
AI376718.1 Clone IMAGE:2066632 embryonic tissue 3' read A
AI571961.1 Clone IMAGE:2223796 pancreas 3' read
AI609248.1 Clone IMAGE:2266302 mouth 3' read
AI634878.1 Clone IMAGE:2297531 kidney 3' read A
AI655359.1 Clone IMAGE:2241991 uncharacterized tissue 3' read A
AI655365.1 Clone IMAGE:2242003 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help