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UGID:160129     UniGene Hs.188591     Homo sapiens (human)   TMEM135
Transmembrane protein 135 (TMEM135)

Human protein-coding gene TMEM135. Represented by 227 ESTs from 108 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 160129 - Hs.188591]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001175336.1 PREDICTED: transmembrane protein 135 isoform 4 P. troglodytes 100.0 457
NP_075069.3 TMEM135 gene product H. sapiens 100.0 457
XP_001104105.1 PREDICTED: transmembrane protein 135 M. mulatta 99.8 457
XP_003910568.1 PREDICTED: transmembrane protein 135-like P. anubis 99.7 318
NP_082619.3 Tmem135 gene product M. musculus 95.6 457
NP_001085541.1 transmembrane protein 135 X. laevis 87.9 452
NP_001082887.1 tmem135 gene product D. rerio 83.4 453
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_002708692.1 PREDICTED: transmembrane protein 135 isoform 1 O. cuniculus 98.2 457
XP_003365410.1 PREDICTED: transmembrane protein 135 isoform 2 E. caballus 98.2 456

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: vascular; brain; testis; lung; intestine; bone marrow; pituitary gland; embryonic tissue; liver; placenta; mixed; uncharacterized tissue; mouth; kidney; eye; uterus; muscle; mammary gland; adrenal gland; cervix; heart; prostate; skin; trachea; thymus; salivary gland; pancreas; parathyroid; blood; lymph node; lymph; connective tissue; ovary; stomach; bone
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q14.2
UniSTS entry: Chr 11 RH94063
UniSTS entry: Chr 11 D11S4582
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BC051462.1 Homo sapiens transmembrane protein 135, mRNA (cDNA clone MGC:57140 IMAGE:5278478), complete cds PA
BX648678.1 Homo sapiens mRNA; cDNA DKFZp686I1974 (from clone DKFZp686I1974) PA
AK000684.1 Homo sapiens cDNA FLJ20677 fis, clone KAIA4183 PA
AK024853.1 Homo sapiens cDNA: FLJ21200 fis, clone COL00269 A
AK025757.1 Homo sapiens cDNA: FLJ22104 fis, clone HEP17633 PA
NM_022918.3 Homo sapiens transmembrane protein 135 (TMEM135), transcript variant 1, mRNA PA
AK225364.1 Homo sapiens mRNA for Hypothetical protein DKFZp686I1974 variant, clone: HEP17633 P
AK291804.1 Homo sapiens cDNA FLJ77427 complete cds P
BC030952.1 Homo sapiens transmembrane protein 135, mRNA (cDNA clone IMAGE:4097312), complete cds PA
AL834493.1 Homo sapiens mRNA; cDNA DKFZp434P0631 (from clone DKFZp434P0631) PA
AK296774.1 Homo sapiens cDNA FLJ55090 complete cds P
AK302473.1 Homo sapiens cDNA FLJ60967 complete cds P
BC012553.1 Homo sapiens transmembrane protein 135, mRNA (cDNA clone IMAGE:4282583), complete cds PA
NM_001168724.1 Homo sapiens transmembrane protein 135 (TMEM135), transcript variant 2, mRNA PA
NR_033149.1 Homo sapiens transmembrane protein 135 (TMEM135), transcript variant 3, non-coding RNA PA

EST sequences (10 of 227) [Show all sequences]

AA977408.1 Clone IMAGE:1590603 kidney 3' read A
AI016734.1 Clone IMAGE:1638508 testis 3' read
AI129652.1 Clone IMAGE:1712940 uterus 3' read
BX093273.1 Clone IMAGp998A16729_;_IMAGE:322071 parathyroid
AI376718.1 Clone IMAGE:2066632 embryonic tissue 3' read A
AI571961.1 Clone IMAGE:2223796 pancreas 3' read
AI609248.1 Clone IMAGE:2266302 mouth 3' read
AI634878.1 Clone IMAGE:2297531 kidney 3' read A
AI655359.1 Clone IMAGE:2241991 uncharacterized tissue 3' read A
AI655365.1 Clone IMAGE:2242003 uncharacterized tissue 3' read A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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