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Myosin, light chain 1, alkali; skeletal, fast (MYL1)
Human protein-coding gene MYL1. Represented by 520 ESTs from 46 cDNA libraries. EST representation biased toward muscle. Corresponds to 2 reference sequences (different isoforms). [UniGene 159879 - Hs.187338]
SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
| Best Hits and Hits from model organisms | Species | Id(%) | Len(aa) |
|
|
MYL1 gene product |
H. sapiens |
100.0 |
193 |
|
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PREDICTED: myosin light chain 1/3, skeletal muscle isoform isoform 3 |
P. troglodytes |
100.0 |
191 |
|
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Myl1 gene product |
M. musculus |
94.7 |
187 |
|
|
myosin, light chain 1, alkali; skeletal, fast |
X. laevis |
86.3 |
189 |
|
|
myl1 gene product |
D. rerio |
67.9 |
189 |
|
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myosin light chain cytoplasmic, isoform A |
D. melanogaster |
54.9 |
144 |
| Other hits (2 of 37) [Show all] | Species | Id(%) | Len(aa) |
|
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PREDICTED: myosin light chain 1/3, skeletal muscle isoform isoform 2 |
C. lupus familiaris |
98.5 |
193 |
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MYL1 gene product |
O. cuniculus |
97.4 |
191 |
GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
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Restricted Expression: |
muscle [show more like this] |
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EST Profile: | Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this] |
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GEO Profiles: |
Experimental gene expression data (Gene Expression Omnibus). |
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cDNA Sources: |
muscle; connective tissue; heart; lung; prostate; eye; pancreas; mixed; larynx; skin; liver; pharynx; uncharacterized tissue; mouth; intestine; embryonic tissue; thymus; mammary gland; placenta; peritoneum |
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
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Chromosome: |
2 |
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Map position: |
2q33-q34 |
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UniSTS entry: |
Chr 2 |
D2S1582E |
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UniSTS entry: |
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D2S2588 |
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SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.
mRNA sequences (8)
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CR456869.1 |
Homo sapiens full open reading frame cDNA clone RZPDo834E0815D for gene MYL1, myosin, light polypeptide 1, alkali; skeletal, fast; complete cds, incl. stopcodon |
P |
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M20643.1 |
Human alkali myosin light chain 3 mRNA, complete cds |
P |
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BC005318.1 |
Homo sapiens myosin, light chain 1, alkali; skeletal, fast, mRNA (cDNA clone MGC:12401 IMAGE:3933998), complete cds |
PA |
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NM_079422.2 |
Homo sapiens myosin, light chain 1, alkali; skeletal, fast (MYL1), transcript variant 3f, mRNA |
P |
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NM_079420.2 |
Homo sapiens myosin, light chain 1, alkali; skeletal, fast (MYL1), transcript variant 1f, mRNA |
PA |
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AK311942.1 |
Homo sapiens cDNA, FLJ92210, Homo sapiens myosin, light polypeptide 1, alkali; skeletal, fast(MYL1), transcript variant 1f, mRNA |
P |
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AK311892.1 |
Homo sapiens cDNA, FLJ92158, Homo sapiens myosin, light polypeptide 1, alkali; skeletal, fast(MYL1), transcript variant 3f, mRNA |
P |
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X05451.1 |
Human mRNA for myosin light chain 3 (MLC-3f) |
P |
EST sequences (10 of 520) [Show all sequences]
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AA993535.1 |
Clone IMAGE:1623232 |
embryonic tissue |
3' read |
A |
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AI033831.1 |
Clone IMAGE:1656509 |
mixed |
3' read |
PA |
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AI093160.1 |
Clone IMAGE:1694756 |
heart |
3' read |
A |
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AI123034.1 |
Clone IMAGE:1509917 |
mixed |
3' read |
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AI141936.1 |
Clone IMAGE:1693453 |
heart |
3' read |
A |
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AI144499.1 |
Clone IMAGE:1705782 |
heart |
3' read |
A |
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AI160496.1 |
Clone IMAGE:1705359 |
heart |
3' read |
PA |
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BX117040.1 |
Clone IMAGp998I16670 |
lung |
5' read |
P |
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AI185164.1 |
Clone IMAGE:1740531 |
lung |
3' read |
A |
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AI200401.1 |
Clone IMAGE:1756921 |
lung |
3' read |
A |
Key to Symbols
P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria
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