> Crystallin, alpha A (CRYAA)
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UGID:159526     UniGene Hs.184085     Homo sapiens (human)   CRYAA Order cDNA clone, Links
Crystallin, alpha A (CRYAA)

Human protein-coding gene CRYAA. Represented by 365 ESTs from 31 cDNA libraries. EST representation biased toward eye; normal. Corresponds to reference sequence NM_000394.2. [UniGene 159526 - Hs.184085]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_514927.2 PREDICTED: uncharacterized protein LOC458589 P. troglodytes 100.0 172
NP_000385.1 CRYAA gene product H. sapiens 100.0 172
XP_003895471.1 PREDICTED: alpha-crystallin A chain P. anubis 100.0 171
NP_038529.1 Cryaa gene product M. musculus 88.8 195
NP_001079340.1 crystallin, alpha A X. laevis 83.5 170
NP_694482.1 cryaa gene product D. rerio 77.5 172
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
NP_001075875.2 CRYAA gene product O. cuniculus 98.8 172
NP_776714.1 CRYAA gene product B. taurus 98.3 172

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: eye [show more like this]
normal [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: eye; kidney; mixed; thymus; liver; cervix; brain; embryonic tissue; placenta
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.3
UniSTS entry: Chr 21 CRYAA_4641
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_000394.2 Homo sapiens crystallin, alpha A (CRYAA), mRNA P
BC069528.1 Homo sapiens crystallin, alpha A, mRNA (cDNA clone MGC:96924 IMAGE:7262133), complete cds P
CR407691.1 Homo sapiens full open reading frame cDNA clone RZPDo834E043D for gene CRYAA, crystallin, alpha A complete cds, without stopcodon P
U05569.1 Human alphaA-crystallin (CRYA1) mRNA, complete cds P
BC113598.1 Homo sapiens crystallin, alpha A, mRNA (cDNA clone MGC:142158 IMAGE:8322650), complete cds P
L25781.1 Homo sapiens alpha-A-crystallin mRNA, 5' end of exon 3
X14789.1 H.sapiens alpha-A crystallin gene exon 1,2 and pseudoexon
U66584.1 Human alphaA-crystallin (CRYAA) mRNA, complete cds P

EST sequences (10 of 365) [Show all sequences]

AA886899.1 Clone IMAGE:1493349 kidney 3' read A
BX118596.1 Clone IMAGp998P14436 eye 5' read P
AI262258.1 Clone IMAGE:1868519 kidney 3' read A
AI271714.1 Clone IMAGE:1866486 kidney 3' read A
AI277590.1 Clone IMAGE:1892686 placenta 3' read A
AI240847.1 Clone IMAGE:1867612 kidney 3' read A
AI472821.1 Clone IMAGE:2146893 mixed 3' read A
AI470866.1 Clone IMAGE:2139268 kidney 3' read A
AI671483.1 Clone IMAGE:2316736 kidney 3' read A
AI671484.1 Clone IMAGE:2316738 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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