> Peroxiredoxin 1 (PRDX1)
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UGID:159178     UniGene Hs.180909     Homo sapiens (human)   PRDX1
Peroxiredoxin 1 (PRDX1)

Human protein-coding gene PRDX1. Represented by 2738 ESTs from 507 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 159178 - Hs.180909]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003891845.1 PREDICTED: peroxiredoxin-1 isoform 6 P. anubis 100.0 216
XP_002801576.1 PREDICTED: peroxiredoxin-1-like M. mulatta 100.0 198
XP_001156568.1 PREDICTED: peroxiredoxin-1 isoform 4 P. troglodytes 100.0 198
NP_001189360.1 PRDX1 gene product H. sapiens 100.0 198
NP_001239094.1 PRDX1 gene product C. lupus familiaris 99.5 198
XP_001496084.1 PREDICTED: peroxiredoxin-1-like E. caballus 99.5 198
XP_002715184.1 PREDICTED: peroxiredoxin 1 O. cuniculus 99.5 198
NP_035164.1 Prdx1 gene product M. musculus 97.0 198
NP_001085178.1 uncharacterized protein LOC432262 X. laevis 89.5 198
NP_001013489.1 prdx1 gene product D. rerio 85.9 198
NP_001122604.1 Protein PRDX-2, isoform b C. elegans 76.8 197
NP_477510.1 thioredoxin peroxidase 1, isoform A D. melanogaster 75.8 193
XP_001699660.1 2-cys peroxiredoxin C. reinhardtii 71.1 196
NP_013684.1 Tsa1p S. cerevisiae 63.1 194
NP_187769.1 2-Cys peroxiredoxin BAS1 A. thaliana 61.5 217
Other hits (2 of 57) [Show all]SpeciesId(%)Len(aa)
NP_476455.1 Prdx1 gene product R. norvegicus 99.0 198
XP_004001967.1 PREDICTED: peroxiredoxin-1 isoform 1 O. aries 98.5 198

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; lung; testis; liver; eye; pancreas; mixed; embryonic tissue; uncharacterized tissue; prostate; placenta; uterus; bladder; intestine; kidney; muscle; ascites; ovary; bone; stomach; cervix; connective tissue; mammary gland; blood; lymph; vascular; heart; bone marrow; salivary gland; pharynx; nerve; spleen; epididymis; lymph node; thyroid; larynx; umbilical cord; parathyroid; pineal gland; adrenal gland; amniotic fluid; mouth; pituitary gland; tonsil; spinal cord; thymus; adipose tissue; esophagus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p34.1
UniSTS entry: RH70158
UniSTS entry: Chr 1 A007G24 [Map Viewer]
UniSTS entry: Chr 1 SHGC-132089
UniSTS entry: Chr 1 D1S2391 [Map Viewer]
UniSTS entry: Prdx1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_181697.2 Homo sapiens peroxiredoxin 1 (PRDX1), transcript variant 3, mRNA PA
NM_181696.2 Homo sapiens peroxiredoxin 1 (PRDX1), transcript variant 2, mRNA PA
AK131049.1 Homo sapiens cDNA FLJ29015 fis, clone MPE08581, highly similar to Peroxiredoxin 1 P
L19184.1 Human natural killer cell enhancing factor (NKEFA) mRNA, complete cds P
NM_002574.3 Homo sapiens peroxiredoxin 1 (PRDX1), transcript variant 1, mRNA PA
CR407652.1 Homo sapiens full open reading frame cDNA clone RZPDo834H022D for gene PRDX1, peroxiredoxin 1 complete cds, without stopcodon P
BT019740.1 Homo sapiens peroxiredoxin 1 mRNA, complete cds P
BC007063.1 Homo sapiens peroxiredoxin 1, mRNA (cDNA clone MGC:12514 IMAGE:3961375), complete cds PA
BC021683.1 Homo sapiens peroxiredoxin 1, mRNA (cDNA clone MGC:24196 IMAGE:3681912), complete cds PA
AK311898.1 Homo sapiens cDNA, FLJ92164, highly similar to Homo sapiens peroxiredoxin 1 (PRDX1), mRNA P
AB451388.1 Homo sapiens PRDX1 mRNA for peroxiredoxin 1, partial cds, clone: FLJ08078AAAF P
AB451262.1 Homo sapiens PRDX1 mRNA for peroxiredoxin 1, complete cds, clone: FLJ08078AAAN P
X67951.1 H.sapiens mRNA for proliferation-associated gene (pag) P
NM_001202431.1 Homo sapiens peroxiredoxin 1 (PRDX1), transcript variant 4, mRNA PA

EST sequences (10 of 2738) [Show all sequences]

AA961338.1 Clone IMAGE:1599458 uncharacterized tissue 3' read P
AA962157.1 Clone IMAGE:1553461 kidney 3' read A
AA976529.1 Clone IMAGE:1587862 uncharacterized tissue 3' read A
AA984482.1 Clone IMAGE:1630102 brain 3' read P
AA991862.1 Clone IMAGE:1610466 uncharacterized tissue 3' read A
AA994772.1 Clone IMAGE:1631281 mammary gland 3' read
AA995421.1 Clone IMAGE:1612042 uncharacterized tissue 3' read
AA906811.1 Clone IMAGE:1519588 uncharacterized tissue 3' read
AI022107.1 Clone IMAGE:1650855 parathyroid 3' read P
AI031932.1 Clone IMAGE:1650011 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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