> H3 histone, family 3B (H3.3B) (H3F3B)
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UGID:159170     UniGene Hs.180877     Homo sapiens (human)   H3F3B
H3 histone, family 3B (H3.3B) (H3F3B)

Human protein-coding gene H3F3B. Represented by 3593 ESTs from 601 cDNA libraries. Corresponds to reference sequence NM_005324.3. [UniGene 159170 - Hs.180877]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_032236.1 H3f3a gene product M. musculus 100.0 135
XP_002732446.1 PREDICTED: histone H3.3B-like isoform 1 S. kowalevskii 100.0 135
XP_001368225.1 PREDICTED: histone H3.3-like M. domestica 100.0 135
XP_003216117.1 PREDICTED: histone H3.3-like A. carolinensis 100.0 135
XP_003400767.1 PREDICTED: histone H3.3-like B. terrestris 100.0 135
XP_003961353.1 PREDICTED: histone H3.3-like T. rubripes 100.0 135
XP_003386893.1 PREDICTED: histone H3.3-like A. queenslandica 100.0 135
XP_001623766.1 predicted protein N. vectensis 100.0 135
NP_001184227.1 LOC100224650 gene product T. guttata 100.0 135
XP_002154470.1 PREDICTED: histone H3.3-like H. magnipapillata 100.0 135
XP_002579313.1 histone H3 S. mansoni 100.0 135
NP_509344.1 Protein HIS-71 C. elegans 100.0 135
NP_001191424.1 histone 3 A. californica 100.0 135
XP_002399568.1 Core histone H2A/H2B/H3/H4 I. scapularis 100.0 135
XP_001949472.1 PREDICTED: histone H3.3-like A. pisum 100.0 135
XP_975889.1 PREDICTED: similar to Histone H3.3B CG8989-PA isoform 2 T. castaneum 100.0 135
NP_001091756.1 h3 histone family 3a B. mori 100.0 135
XP_001657554.1 histone H3.3 A. aegypti 100.0 135
XP_321242.1 AGAP001813-PA A. gambiae 100.0 135
XP_001867328.1 histone H3.3 type 2 C. quinquefasciatus 100.0 135
NP_511095.1 histone H3.3B, isoform A D. melanogaster 100.0 135
XP_002078203.1 GD23319 D. simulans 100.0 135
XP_001608166.1 PREDICTED: histone H3.3-like isoform 2 N. vitripennis 100.0 135
XP_001120696.1 PREDICTED: histone H3.3-like isoform 1 A. mellifera 100.0 135
XP_791401.1 PREDICTED: histone H3.3-like S. purpuratus 100.0 135
XP_002119783.1 PREDICTED: histone H3.3-like C. intestinalis 100.0 135
XP_002589240.1 hypothetical protein BRAFLDRAFT_120760 B. floridae 100.0 135
XP_002664801.1 PREDICTED: histone H3.3-like isoform 2 D. rerio 100.0 135
XP_004080398.1 PREDICTED: histone H3.3-like O. latipes 100.0 135
XP_003438715.1 PREDICTED: histone H3.3-like O. niloticus 100.0 135
NP_001080065.1 H3 histone, family 3B (H3.3B) X. laevis 100.0 135
XP_002940033.1 PREDICTED: histone H3.3 X. tropicalis 100.0 135
XP_003643522.1 PREDICTED: histone H3.3-like G. gallus 100.0 135
XP_003211494.1 PREDICTED: histone H3.3-like M. gallopavo 100.0 135
XP_001091581.1 PREDICTED: histone H3.3-like isoform 1 M. mulatta 100.0 135
NP_001162389.1 histone H3.1 P. anubis 100.0 135
NP_001092038.1 HIST1H3A gene product P. troglodytes 100.0 135
NP_002098.1 H3F3A gene product H. sapiens 100.0 135
XP_537232.1 PREDICTED: histone H3.3 isoform 1 C. lupus familiaris 100.0 135
XP_001495110.1 PREDICTED: histone H3.3-like isoform 1 E. caballus 100.0 135
XP_003131242.1 PREDICTED: histone H3.3-like S. scrofa 100.0 135
NP_001229500.1 H3F3B gene product B. taurus 100.0 135
XP_004013172.1 PREDICTED: histone H3.3 O. aries 100.0 135
NP_001164583.1 H3.3A gene product O. cuniculus 100.0 135
NP_001078517.1 histone H3 A. thaliana 97.1 135
XP_956003.1 histone H3 N. crassa 96.3 135
NP_009564.1 Hht1p S. cerevisiae 95.6 135
XP_001690671.1 histone H3 C. reinhardtii 95.6 134
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_001514437.1 PREDICTED: histone H3.2-like O. anatinus 98.5 135
XP_001753449.1 histone H3 P. patens 97.8 135

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; pharynx; testis; embryonic tissue; pancreas; skin; uterus; uncharacterized tissue; eye; placenta; blood; mixed; liver; kidney; prostate; bone marrow; mammary gland; intestine; ovary; stomach; heart; muscle; bone; connective tissue; lymph; salivary gland; ascites; lymph node; spleen; cervix; bladder; thymus; tonsil; mouth; thyroid; pituitary gland; parathyroid; spinal cord; vascular; adrenal gland; esophagus; epididymis; ear; umbilical cord; nerve; larynx; ganglia; adipose tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q25.1
UniSTS entry: Chr 17 RH47096 [Map Viewer]
UniSTS entry: Chr 17 RH16041 [Map Viewer]
UniSTS entry: Chr 17 G59779
UniSTS entry: Chr 17 G43578
UniSTS entry: Chr 17 RH11839
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

BX537379.1 Homo sapiens mRNA; cDNA DKFZp686C2282 (from clone DKFZp686C2282); complete cds PA
BX647280.1 Homo sapiens mRNA; cDNA DKFZp686O0399 (from clone DKFZp686O0399) PA
AK130772.1 Homo sapiens cDNA FLJ27262 fis, clone TMS00164, highly similar to Histone H3.3 P
NM_005324.3 Homo sapiens H3 histone, family 3B (H3.3B) (H3F3B), mRNA PA
BC108701.1 Homo sapiens H3 histone, family 3B (H3.3B), mRNA (cDNA clone MGC:131844 IMAGE:6144255), complete cds PA
AF218029.1 Homo sapiens clone PP781 unknown mRNA PA
BC001124.2 Homo sapiens H3 histone, family 3B (H3.3B), mRNA (cDNA clone MGC:2161 IMAGE:2988279), complete cds PA
BC006497.2 Homo sapiens H3 histone, family 3B (H3.3B), mRNA (cDNA clone MGC:2160 IMAGE:2959756), complete cds PA
BC012813.2 Homo sapiens H3 histone, family 3B (H3.3B), mRNA (cDNA clone MGC:4123 IMAGE:2959756), complete cds PA
AK054591.1 Homo sapiens cDNA FLJ30029 fis, clone 3NB692001334
BC017558.1 Homo sapiens H3 histone, family 3B (H3.3B), mRNA (cDNA clone MGC:9614 IMAGE:3910031), complete cds PA
AK312762.1 Homo sapiens cDNA, FLJ93172, highly similar to Homo sapiens H3 histone, family 3B (H3.3B) (H3F3B), mRNA P
AK304607.1 Homo sapiens cDNA FLJ52843 complete cds, highly similar to Histone H3.3 P
BC020466.1 Homo sapiens H3 histone, family 3B (H3.3B), mRNA (cDNA clone IMAGE:3870030) PA

EST sequences (10 of 3593) [Show all sequences]

AA954729.1 Clone IMAGE:1572888 kidney 3' read A
AA971497.1 Clone IMAGE:1584370 lung 3' read A
AA973674.1 Clone IMAGE:1568984 lung 3' read A
AA974852.1 Clone IMAGE:1567744 lung 3' read A
AA988234.1 Clone IMAGE:1604784 lung 3' read A
AA993668.1 Clone IMAGE:1623623 embryonic tissue 3' read A
AA994288.1 Clone IMAGE:1631211 mammary gland 3' read P
AA902835.1 Clone IMAGE:1519525 uncharacterized tissue 3' read P
AI002634.1 Clone IMAGE:1629132 mixed 3' read A
AI002775.1 Clone IMAGE:1699247 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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