> Proteolipid protein 1 (PLP1)
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UGID:131085     UniGene Hs.1787     Homo sapiens (human)   PLP1 Order cDNA clone, Links
Proteolipid protein 1 (PLP1)

Human protein-coding gene PLP1. Represented by 6917 ESTs from 189 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 131085 - Hs.1787]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_035253.1 Plp1 gene product M. musculus 100.0 276
NP_112252.1 Plp1 gene product R. norvegicus 100.0 276
XP_001087984.2 PREDICTED: myelin proteolipid protein-like isoform 1 M. mulatta 100.0 276
XP_003918121.1 PREDICTED: myelin proteolipid protein isoform 1 P. anubis 100.0 276
XP_001141683.1 PREDICTED: myelin proteolipid protein isoform 10 P. troglodytes 100.0 276
NP_001122306.1 PLP1 gene product H. sapiens 100.0 276
NP_001013856.1 myelin proteolipid protein C. lupus familiaris 100.0 276
XP_001493124.1 PREDICTED: myelin proteolipid protein-like isoform 2 E. caballus 100.0 276
NP_999139.1 PLP1 gene product S. scrofa 100.0 276
NP_776574.2 PLP1 gene product B. taurus 100.0 276
XP_004022513.1 PREDICTED: myelin proteolipid protein isoform 1 O. aries 100.0 276
NP_001075797.1 PLP1 gene product O. cuniculus 100.0 276
NP_001082268.1 myelin proteolipid protein A X. laevis 82.0 278
NP_783166.1 plp1a gene product D. rerio 63.9 244
Other hits (2 of 12) [Show all]SpeciesId(%)Len(aa)
XP_001513739.2 PREDICTED: myelin proteolipid protein-like, partial O. anatinus 98.8 241
NP_990608.1 PLP1 gene product G. gallus 97.1 276

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; skin; testis; uncharacterized tissue; spinal cord; nerve; ear; ganglia; mammary gland; embryonic tissue; eye; trachea; amniotic fluid; intestine; adrenal gland; prostate; thymus; mixed; uterus; muscle; lung; pharynx; ovary; heart; blood; placenta; parathyroid; spleen
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xq22
UniSTS entry: Chr X PMC311008P1
UniSTS entry: Plp1
UniSTS entry: Chr X SHGC-63459
UniSTS entry: Chr X DXS8149
UniSTS entry: Chr X DXS9790
UniSTS entry: PLP2
UniSTS entry: Plp1
UniSTS entry: Chr X GDB:370833
UniSTS entry: Chr X PLP1_1059
UniSTS entry: Chr 15 Rnu2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AK128782.1 Homo sapiens cDNA FLJ45458 fis, clone BRSTN2010107, highly similar to Myelin proteolipid protein P
NM_199478.1 Homo sapiens proteolipid protein 1 (PLP1), transcript variant 2, mRNA PA
CR536542.1 Homo sapiens full open reading frame cDNA clone RZPDo834G0620D for gene PLP1, proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); complete cds, incl. stopcodon P
BT019602.1 Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) mRNA, complete cds P
BT019601.1 Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) mRNA, complete cds P
BC095452.1 Homo sapiens proteolipid protein 1, mRNA (cDNA clone MGC:111218 IMAGE:30717624), complete cds PA
M54927.1 Human myelin proteolipid protein mRNA, complete cds P
M27110.1 Human proteolipid protein mRNA (PLP), complete cds P
M17085.1 Human CNS myelin major proteolipid component (DM-20) mRNA, complete cds P
NM_000533.3 Homo sapiens proteolipid protein 1 (PLP1), transcript variant 1, mRNA PA
BC002665.1 Homo sapiens proteolipid protein 1, mRNA (cDNA clone MGC:3940 IMAGE:3606269), complete cds PA
AK292728.1 Homo sapiens cDNA FLJ77822 complete cds, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA P
AK309239.1 Homo sapiens cDNA, FLJ99280 P
AK308966.1 Homo sapiens cDNA, FLJ99007 P
AK312340.1 Homo sapiens cDNA, FLJ92659, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA P
NM_001128834.1 Homo sapiens proteolipid protein 1 (PLP1), transcript variant 3, mRNA PA
AK295388.1 Homo sapiens cDNA FLJ54051 complete cds, highly similar to Myelin proteolipid protein P
AK295374.1 Homo sapiens cDNA FLJ54326 complete cds, highly similar to Myelin proteolipid protein P

EST sequences (10 of 6917) [Show all sequences]

R15774.1 Clone IMAGE:53364 brain 3' read
R16280.1 Clone IMAGE:53364 brain 5' read
AA908914.1 Clone IMAGE:1537428 ganglia 3' read A
R18062.1 Clone IMAGE:32464 brain 5' read
R18637.1 Clone IMAGE:30618 brain 5' read
R19453.1 Clone IMAGE:33588 brain 5' read
AI039814.1 Clone IMAGE:1659663 embryonic tissue 3' read A
R19586.1 Clone IMAGE:33453 brain 5' read
R20341.1 Clone IMAGE:32704 brain 5' read
AI073400.1 Clone IMAGE:1640348 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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