Adenylate kinase 1 (AK1)

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UGID:158583 UniGene Hs.175473 Homo sapiens (human) AK1

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Adenylate kinase 1 (AK1)

Human protein-coding gene AK1. Represented by 415 ESTs from 198 cDNA libraries. Corresponds to reference sequence NM_000476.2. [UniGene 158583 - Hs.175473]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_000467.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	AK1 gene product	H. sapiens	100.0	193
XP_003951582.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: adenylate kinase isoenzyme 1	P. troglodytes	99.5	210
XP_003911960.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: adenylate kinase isoenzyme 1	P. anubis	99.5	209
NP_001185719.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Ak1 gene product	M. musculus	91.2	193
NP_001085451.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	adenylate kinase 1	X. laevis	81.4	193
NP_001003993.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ak1 gene product	D. rerio	77.3	193
NP_509884.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein F38B2.4	C. elegans	63.1	194
NP_524038.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	adenylate kinase-1, isoform A	D. melanogaster	54.4	195
XP_001690042.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ODA5-associated flagellar adenylate kinase	C. reinhardtii	49.8	597
NP_012901.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	bifunctional uridylate/adenylate kinase	S. cerevisiae	47.8	184
NP_850868.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Uridylate kinase	A. thaliana	46.7	184
Other hits (2 of 47) [Show all]		Species	Id(%)	Len(aa)
XP_002800218.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: adenylate kinase isoenzyme 1 isoform 2	M. mulatta	99.2	244
NP_001124519.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	adenylate kinase isoenzyme 1	C. lupus familiaris	98.1	209

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; muscle; lung; testis; pancreas; mixed; intestine; heart; liver; uncharacterized tissue; uterus; eye; vascular; blood; thyroid; ovary; salivary gland; stomach; mammary gland; cervix; skin; connective tissue; placenta; adipose tissue; trachea; umbilical cord; ascites; parathyroid; spleen; mouth; bone; prostate; kidney; embryonic tissue; amniotic fluid; nerve; epididymis; bladder; pineal gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	9
Map position:	9q34.1
UniSTS entry:	Chr 9	G44718
UniSTS entry:		D8S1362E
UniSTS entry:	Chr 9	SHGC-31174	[Map Viewer]
UniSTS entry:	Chr 9	SHGC-31625
UniSTS entry:	Chr 1	D10S16

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AB021871.1	Homo sapiens hAK1 mRNA for adenylate kinase 1, complete cds	P
NM_000476.2	Homo sapiens adenylate kinase 1 (AK1), mRNA	P
CR542004.1	Homo sapiens full open reading frame cDNA clone RZPDo834F0135D for gene AK1, adenylate kinase 1; complete cds, without stopcodon	P
CR541977.1	Homo sapiens full open reading frame cDNA clone RZPDo834C0135D for gene AK1, adenylate kinase 1; complete cds, incl. stopcodon	P
BT019580.1	Homo sapiens adenylate kinase 1 mRNA, complete cds	P
AK223501.1	Homo sapiens mRNA for adenylate kinase 1 variant, clone: FCC121D04	P
BC100022.1	Homo sapiens adenylate kinase 1, mRNA (cDNA clone MGC:111346 IMAGE:30561924), complete cds	PA
BC001116.2	Homo sapiens adenylate kinase 1, mRNA (cDNA clone MGC:1808 IMAGE:2988248), complete cds	PA
AK313758.1	Homo sapiens cDNA, FLJ94359, Homo sapiens adenylate kinase 1 (AK1), mRNA	P

EST sequences (10 of 415) [Show all sequences]

AA962540.1	Clone IMAGE:1602207	lung	3' read	P
AA970035.1	Clone IMAGE:1581608	mixed	3' read
AA977436.1	Clone IMAGE:1591068	kidney	3' read	P
AA989461.1	Clone IMAGE:1607753	mammary gland	3' read	P
AA992533.1	Clone IMAGE:1621990	embryonic tissue	3' read	A
AA994010.1	Clone IMAGE:1628942	mixed	3' read	PA
AI001757.1	Clone IMAGE:1619104	testis	3' read	P
AA926853.1	Clone IMAGE:1540356	mixed	3' read	P
AI027933.1	Clone IMAGE:1643976	testis	3' read
AI028320.1	Clone IMAGE:1644616	testis	3' read	PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria