> Activin A receptor, type IIB (ACVR2B)
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UGID:158480     UniGene Hs.174273     Homo sapiens (human)   ACVR2B
Activin A receptor, type IIB (ACVR2B)

Human protein-coding gene ACVR2B. Represented by 98 ESTs from 62 cDNA libraries. Corresponds to reference sequence NM_001106.3. [UniGene 158480 - Hs.174273]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_516369.2 PREDICTED: activin receptor type-2B isoform 3 P. troglodytes 100.0 511
NP_001097.2 ACVR2B gene product H. sapiens 100.0 511
XP_001084713.1 PREDICTED: activin receptor type-2B M. mulatta 100.0 504
XP_542709.1 PREDICTED: activin receptor type-2B C. lupus familiaris 100.0 495
XP_003894716.1 PREDICTED: activin receptor type-2B P. anubis 99.8 524
XP_001488786.2 PREDICTED: activin receptor type-2B E. caballus 99.8 494
NP_113742.1 Acvr2b gene product R. norvegicus 99.6 511
NP_001005350.1 ACVR2B gene product S. scrofa 99.6 511
NP_031423.1 Acvr2b gene product M. musculus 99.1 535
NP_001081479.1 activin receptor precursor X. laevis 87.9 503
NP_571285.1 acvr2b gene product D. rerio 82.7 508
NP_731926.1 punt, isoform A D. melanogaster 61.0 490
NP_001021148.1 Protein DAF-4, isoform c C. elegans 45.9 183
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
NP_776920.1 ACVR2B gene product B. taurus 99.0 511
XP_001379246.1 PREDICTED: activin receptor type-2B-like M. domestica 96.0 502

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; embryonic tissue; prostate; skin; brain; esophagus; eye; mammary gland; uncharacterized tissue; stomach; heart; intestine; testis; mixed; kidney; pituitary gland; thymus; ear; lung; pancreas; ovary; connective tissue; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p22
UniSTS entry: Chr 3 STS-N30308
UniSTS entry: Chr 3 RH99151
UniSTS entry: Chr 3 MARC_4816-4817:991938566:3
UniSTS entry: Chr 3 Acvr2b
UniSTS entry: Chr 3 PMC202382P2
UniSTS entry: Chr 3 RH65433 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AF075005.1 Homo sapiens full length insert cDNA YH98E06 PA
NM_001106.3 Homo sapiens activin A receptor, type IIB (ACVR2B), mRNA P
BC096244.1 Homo sapiens activin A receptor, type IIB, mRNA (cDNA clone MGC:116907 IMAGE:40005761), complete cds P
BC096243.1 Homo sapiens activin A receptor, type IIB, mRNA (cDNA clone MGC:116906 IMAGE:40005760), complete cds P
BC096245.1 Homo sapiens activin A receptor, type IIB, mRNA (cDNA clone MGC:116909 IMAGE:40005763), complete cds P
BC099642.4 Homo sapiens activin A receptor, type IIB, mRNA (cDNA clone MGC:116908 IMAGE:40005762), complete cds P
X77533.1 H.sapiens mRNA for activin type II receptor P

EST sequences (10 of 98) [Show all sequences]

AI024361.1 Clone IMAGE:1643196 testis 3' read
AI032142.1 Clone IMAGE:1611279 uncharacterized tissue 3' read A
AI143544.1 Clone IMAGE:1708501 heart 3' read P
BX103402.1 Clone IMAGp998N13196_;_IMAGE:136908 placenta PA
BX117458.1 Clone IMAGp998G205320_;_IMAGE:2154667 intestine A
BX090446.1 Clone IMAGp998E03562_;_IMAGE:258026 placenta
AI188710.1 Clone IMAGE:1723859 placenta 3' read A
R25973.1 Clone IMAGE:132603 placenta 5' read A
R26777.1 Clone IMAGE:132603 placenta 3' read
AI219028.1 Clone IMAGE:1759656 placenta 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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