> Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL)
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UGID:158449     UniGene Hs.174103     Homo sapiens (human)   ITGAL Order cDNA clone, Links
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL)

Human protein-coding gene ITGAL. Represented by 232 ESTs from 86 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 158449 - Hs.174103]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002200.2 ITGAL gene product H. sapiens 100.0 1169
NP_001029341.1 ITGAL gene product P. troglodytes 99.6 1169
NP_001240803.1 Itgal gene product M. musculus 76.6 1153
Other hits (2 of 12) [Show all]SpeciesId(%)Len(aa)
XP_003918725.1 PREDICTED: integrin alpha-L P. anubis 96.7 1085
XP_001100800.1 PREDICTED: integrin alpha-L M. mulatta 96.4 842

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: thymus; lymph node; spleen; uncharacterized tissue; blood; adrenal gland; bone marrow; brain; lung; testis; uterus; placenta; muscle; thyroid; prostate; pharynx; lymph; mouth; trachea; mixed; stomach; mammary gland; kidney; liver; intestine; ganglia; eye
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p11.2
UniSTS entry: Chr 1 D1S1425
UniSTS entry: RH80563
UniSTS entry: Chr 16 RH48619
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_002209.2 Homo sapiens integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL), transcript variant 1, mRNA PA
BC008777.2 Homo sapiens integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), mRNA (cDNA clone MGC:1714 IMAGE:3142951), complete cds PA
Y00796.1 Human mRNA for leukocyte-associated molecule-1 alpha subunit (LFA-1 alpha subunit) PA
AK314246.1 Homo sapiens cDNA, FLJ94991, highly similar to Homo sapiens integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL), mRNA P
NM_001114380.1 Homo sapiens integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL), transcript variant 2, mRNA PA
AK298674.1 Homo sapiens cDNA FLJ56671 complete cds, highly similar to Integrin alpha-L precursor P
AK303190.1 Homo sapiens cDNA FLJ57691 complete cds, highly similar to Integrin alpha-L precursor P

EST sequences (10 of 232) [Show all sequences]

AA989388.1 Clone IMAGE:1606160 kidney 3' read A
BX114703.1 Clone IMAGp998G08241_;_IMAGE:154015 mammary gland
AI350394.1 Clone IMAGE:1947826 uncharacterized tissue 3' read
R48903.1 Clone IMAGE:154015 mammary gland 5' read
F30979.1 Clone s4000095B09 muscle
F36551.1 Clone sH5-000016-0/G07 muscle A
BX457402.2 Clone CS0CAP008YM19 thymus 5' read P
BX481782.1 Clone DKFZp686J03227 muscle 5' read P
BX485565.1 Clone DKFZp686K20247 muscle 5' read P
CD687484.1 pharynx


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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