> NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (NDUFS2)
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UGID:158381     UniGene Hs.173611     Homo sapiens (human)   NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (NDUFS2)

Human protein-coding gene NDUFS2. Represented by 863 ESTs from 333 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 158381 - Hs.173611]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001065294.1 NDUFS2 gene product P. troglodytes 100.0 462
NP_004541.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 1 precursor H. sapiens 100.0 462
NP_694704.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial precursor M. musculus 96.5 462
NP_001089829.1 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) X. laevis 92.8 458
NP_001018481.2 NADH dehydrogenase (ubiquinone) Fe-S protein 2 D. rerio 91.7 458
NP_651926.1 CG1970, isoform A D. melanogaster 84.2 462
NP_510569.1 Protein GAS-1 C. elegans 75.3 469
NP_085511.1 NADH dehydrogenase subunit 7 A. thaliana 74.5 392
XP_965665.2 NADH:ubiquinone oxidoreductase 49kD subunit N. crassa 74.1 396
XP_001697607.1 NADH:ubiquinone oxidoreductase 49 kDa ND7 subunit C. reinhardtii 71.1 459
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_003893006.1 PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 1 P. anubis 99.3 462
XP_001117968.1 PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 5 M. mulatta 99.1 462

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; liver; intestine; lung; prostate; eye; placenta; embryonic tissue; uncharacterized tissue; uterus; muscle; testis; kidney; ovary; blood; heart; thymus; pancreas; mammary gland; bone; lymph; trachea; umbilical cord; tonsil; parathyroid; ascites; stomach; mixed; pharynx; connective tissue; adrenal gland; cervix; bone marrow; spleen; nerve; mouth; bladder; esophagus; larynx; vascular; thyroid; salivary gland; ganglia; lymph node; adipose tissue; peritoneum
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q23
UniSTS entry: Chr 1 RH70304 [Map Viewer]
UniSTS entry: Chr 11 RH103676
UniSTS entry: Chr 11 RH80357
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AF050640.1 Homo sapiens NADH-ubiquinone oxidoreductase NDUFS2 subunit mRNA, nuclear gene encoding mitochondrial protein, complete cds PA
AF013160.1 Homo sapiens NADH dehydrogenase-ubiquinone Fe-S protein 2 precursor mRNA, nuclear gene encoding mitochondrial protein, complete cds PA
NM_004550.4 Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (NDUFS2), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
AK222618.1 Homo sapiens mRNA for NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) variant, clone: CBL00455 PA
BC001456.1 Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase), mRNA (cDNA clone MGC:1957 IMAGE:3138814), complete cds PA
BC000170.2 Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase), mRNA (cDNA clone MGC:5127 IMAGE:2899956), complete cds PA
BC008868.2 Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase), mRNA (cDNA clone MGC:15322 IMAGE:4131430), complete cds PA
AK314807.1 Homo sapiens cDNA, FLJ95682 P
AK309871.1 Homo sapiens cDNA, FLJ99912 P
Z36812.1 H.sapiens (xs16) mRNA, 372bp
AK315977.1 Homo sapiens cDNA, FLJ78876 complete cds, highly similar to NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial precursor (EC 1.6.5.3) P
AK301641.1 Homo sapiens cDNA FLJ53932 complete cds, highly similar to NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial precursor (EC 1.6.5.3) P
NM_001166159.1 Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (NDUFS2), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA PA

EST sequences (10 of 863) [Show all sequences]

AA836846.1 Clone IMAGE:1422681 kidney PA
AA992183.1 Clone IMAGE:1623081 embryonic tissue 3' read
R18114.1 Clone IMAGE:125010 mixed 5' read
R18115.1 Clone IMAGE:125010 mixed 3' read
AI052375.1 Clone IMAGE:1676147 embryonic tissue 3' read PA
AA946663.1 Clone IMAGE:1589137 kidney 3' read PA
BX090189.1 Clone IMAGp998N19122_;_IMAGE:125010 mixed
CB145836.1 Clone L16HLK3-11-D12 liver 5' read P
CB157741.1 Clone L18POOL1n1-3-F10 liver 5' read P
CB107605.1 Clone L3SNU475-18-E01 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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