Collagen, type I, alpha 1 (COL1A1)

Restricted Expression:

embryoid body [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

embryonic tissue; bone; eye; lung; skin; uncharacterized tissue; mammary gland; intestine; pancreas; bone marrow; placenta; connective tissue; ear; mixed; brain; ovary; stomach; thyroid; uterus; heart; mouth; amniotic fluid; larynx; bladder; kidney; epididymis; lymph; spleen; esophagus; nerve; prostate; vascular; testis; muscle; pituitary gland; liver; salivary gland; ganglia; adrenal gland; umbilical cord; pharynx; blood; lymph node; adipose tissue; thymus

NCBI

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Finding cDNAs

UGID:158287 UniGene Hs.172928 Homo sapiens (human) COL1A1

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Collagen, type I, alpha 1 (COL1A1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001169386.1	PREDICTED: similar to alpha 1 type I collagen preproprotein isoform 8	P. troglodytes	100.0	1463
NP_000079.2	alpha 1 type I collagen preproprotein	H. sapiens	100.0	1463
XP_001096194.1	PREDICTED: similar to Collagen alpha-1(I) chain precursor	M. mulatta	99.6	1251
NP_031768.2	collagen, type I, alpha 1 precursor	M. musculus	97.9	1452
NP_001080821.1	collagen, type I, alpha 1	X. laevis	88.5	1448
NP_954684.1	collagen, type I, alpha 1	D. rerio	84.7	1446
NP_001138064.1	CG42342, isoform F	D. melanogaster	47.9	576
NP_001022663.1	abnormal EMBroygenesis family member (emb-9)	C. elegans	46.8	1284

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	17
Map position:	17q21.33
UniSTS entry:	Chr 17	WI-18942
UniSTS entry:	Chr 17	(n/a)
UniSTS entry:	Chr 17	RH45119
UniSTS entry:	Chr 17	(n/a)
UniSTS entry:	Chr 17	(n/a)
UniSTS entry:	Chr 17	SGC32927
UniSTS entry:	Chr 17	GDB:177260
UniSTS entry:	Chr 17	RH77855
UniSTS entry:	Chr 17	(n/a)
UniSTS entry:	Chr 17	(n/a)

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_000088.3	Homo sapiens collagen, type I, alpha 1 (COL1A1), mRNA	P
K01228.1	Human proalpha 1 (I) chain of type I procollagen mRNA (partial)	P
AB209597.1	Homo sapiens mRNA for Collagen alpha 1 chain precursor variant protein	P
Z74615.1	H.sapiens mRNA for prepro-alpha1(I) collagen	P
BC036531.2	Homo sapiens collagen, type I, alpha 1, mRNA (cDNA clone MGC:33668 IMAGE:5264710), complete cds	PA
X06269.1	Human mRNA for pro-1(I)collagen chain (Col1A1)	P
X07884.1	Human mRNA for alpha-1(I) chain of procollagen type I	P
M36546.1	Human alpha-1 collagen type I mRNA, 5' end	P
AK297731.1	Homo sapiens cDNA FLJ51252 complete cds, highly similar to Collagen alpha-1(I) chain precursor	P
S64596.1	COL1A1=type I collagen pro alpha 1(I) chain propeptide {3' region} [human, fetal cells 86-237, 86-146, 88-251, mRNA Partial Mutant, 855 nt]	P

EST sequences (10 of 3500) [Show all sequences]

AA961662.1	Clone IMAGE:1592694	kidney	3' read	PA
AA961963.1	Clone IMAGE:1593803	kidney	3' read	P
AA864333.1	Clone IMAGE:1470682	uncharacterized tissue	3' read	A
AA975668.1	Clone IMAGE:1591055	kidney	3' read	P
AA977821.1	Clone IMAGE:1592444	kidney	3' read	P
AA978078.1	Clone IMAGE:1590866	kidney	3' read	A
AA983262.1	Clone IMAGE:1592488	kidney	3' read	P
AA985449.1	Clone IMAGE:1594166	kidney	3' read	PA
AA985499.1	Clone IMAGE:1592932	kidney	3' read
AA987731.1	Clone IMAGE:1593998	kidney	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria