> Collagen, type I, alpha 1 (COL1A1)
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UGID:158287     UniGene Hs.172928     Homo sapiens (human)   COL1A1 Order cDNA clone, Links
Collagen, type I, alpha 1 (COL1A1)

Human protein-coding gene COL1A1. Represented by 3638 ESTs from 529 cDNA libraries. EST representation biased toward embryoid body. Corresponds to reference sequence NM_000088.3. [UniGene 158287 - Hs.172928]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001169409.1 PREDICTED: collagen alpha-1(I) chain isoform 9 P. troglodytes 100.0 1463
NP_000079.2 COL1A1 gene product H. sapiens 100.0 1463
XP_001096194.2 PREDICTED: hypothetical protein LOC574201 M. mulatta 99.7 1431
XP_003912777.1 PREDICTED: LOW QUALITY PROTEIN: collagen alpha-1(I) chain P. anubis 99.7 1465
NP_031768.2 Col1a1 gene product M. musculus 98.2 1452
NP_001080821.1 collagen, type I, alpha 1 precursor X. laevis 88.3 1448
NP_954684.1 col1a1a gene product D. rerio 84.3 1446
NP_001247141.1 CG42342, isoform J D. melanogaster 49.1 440
NP_001022662.1 Protein EMB-9, isoform a C. elegans 48.4 1498
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
NP_001003090.1 COL1A1 gene product C. lupus familiaris 99.3 1459
NP_001029211.1 COL1A1 gene product B. taurus 99.2 1462

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: embryoid body [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; bone; lung; eye; uncharacterized tissue; skin; mammary gland; intestine; pancreas; placenta; bone marrow; ear; connective tissue; mixed; ovary; brain; stomach; heart; thyroid; uterus; mouth; amniotic fluid; larynx; bladder; kidney; testis; epididymis; spleen; prostate; esophagus; nerve; vascular; muscle; pharynx; liver; adrenal gland; umbilical cord; blood; pituitary gland; lymph node; salivary gland; ganglia; lymph; adipose tissue; thymus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q21.33
UniSTS entry: Chr 17 WI-18942 [Map Viewer]
UniSTS entry: Chr 17 fj67h06.x1
UniSTS entry: Chr 17 RH45119 [Map Viewer]
UniSTS entry: Chr 17 MARC_5785-5786:997299286:1
UniSTS entry: Chr 17 SGC32927 [Map Viewer]
UniSTS entry: Chr 17 COL1A1
UniSTS entry: Chr 12 GDB:177260
UniSTS entry: Chr 17 RH77855 [Map Viewer]
UniSTS entry: Chr 17 PMC34669P1
UniSTS entry: Chr 17 MARC_5219-5220:996690145:1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_000088.3 Homo sapiens collagen, type I, alpha 1 (COL1A1), mRNA P
K01228.1 Human proalpha 1 (I) chain of type I procollagen mRNA (partial) P
AB209597.1 Homo sapiens mRNA for Collagen alpha 1 chain precursor variant protein P
Z74615.1 H.sapiens mRNA for prepro-alpha1(I) collagen P
BC036531.2 Homo sapiens collagen, type I, alpha 1, mRNA (cDNA clone MGC:33668 IMAGE:5264710), complete cds PA
X06269.1 Human mRNA for pro-1(I)collagen chain (Col1A1) P
X07884.1 Human mRNA for alpha-1(I) chain of procollagen type I P
M36546.1 Human alpha-1 collagen type I mRNA, 5' end P
AK297731.1 Homo sapiens cDNA FLJ51252 complete cds, highly similar to Collagen alpha-1(I) chain precursor P
JQ236861.1 Homo sapiens collagen alpha-1(I) chain preproprotein (COL1A1) mRNA, complete cds P
S64596.1 COL1A1=type I collagen pro alpha 1(I) chain propeptide {3' region} [human, fetal cells 86-237, 86-146, 88-251, mRNA Partial Mutant, 855 nt] P

EST sequences (10 of 3638) [Show all sequences]

AA836794.1 Clone IMAGE:1422611 kidney
AA961662.1 Clone IMAGE:1592694 kidney 3' read A
AA961963.1 Clone IMAGE:1593803 kidney 3' read P
AA962587.1 Clone IMAGE:1597777 uncharacterized tissue 3' read
AA864333.1 Clone IMAGE:1470682 uncharacterized tissue 3' read A
AA975668.1 Clone IMAGE:1591055 kidney 3' read
AA977821.1 Clone IMAGE:1592444 kidney 3' read
AA978078.1 Clone IMAGE:1590866 kidney 3' read A
AA983262.1 Clone IMAGE:1592488 kidney 3' read
AA985449.1 Clone IMAGE:1594166 kidney 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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