> S-phase kinase-associated protein 1 (SKP1)
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UGID:158089     UniGene Hs.171626     Homo sapiens (human)   SKP1
S-phase kinase-associated protein 1 (SKP1)

Human protein-coding gene SKP1. Represented by 1827 ESTs from 397 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 158089 - Hs.171626]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001166207.2 PREDICTED: s-phase kinase-associated protein 1-like isoform 5 P. troglodytes 100.0 173
XP_002723199.1 PREDICTED: S-phase kinase-associated protein 1 isoform 2 O. cuniculus 100.0 167
NP_035673.3 Skp1a gene product M. musculus 100.0 162
NP_001007609.1 Skp1 gene product R. norvegicus 100.0 162
XP_001365828.1 PREDICTED: s-phase kinase-associated protein 1-like isoform 1 M. domestica 100.0 162
XP_003217442.1 PREDICTED: s-phase kinase-associated protein 1-like A. carolinensis 100.0 162
XP_003971025.1 PREDICTED: S-phase kinase-associated protein 1-like T. rubripes 100.0 162
XP_002189695.1 PREDICTED: S-phase kinase-associated protein 1 T. guttata 100.0 162
NP_957037.1 skp1 gene product D. rerio 100.0 162
NP_001187838.1 S-phase kinase-associated protein 1 I. punctatus 100.0 162
NP_001134437.1 S-phase kinase-associated protein 1 S. salar 100.0 162
XP_004076110.1 PREDICTED: S-phase kinase-associated protein 1-like isoform 1 O. latipes 100.0 162
XP_003451485.1 PREDICTED: S-phase kinase-associated protein 1-like O. niloticus 100.0 162
NP_001080844.1 S-phase kinase-associated protein 1 X. laevis 100.0 162
NP_001016519.1 skp1 gene product X. tropicalis 100.0 162
NP_001006153.1 SKP1 gene product G. gallus 100.0 162
XP_003210511.1 PREDICTED: s-phase kinase-associated protein 1-like M. gallopavo 100.0 162
NP_001180519.1 s-phase kinase-associated protein 1 M. mulatta 100.0 162
XP_003900151.1 PREDICTED: S-phase kinase-associated protein 1 isoform 1 P. anubis 100.0 162
NP_733779.1 SKP1 gene product H. sapiens 100.0 162
NP_001239337.1 SKP1 gene product C. lupus familiaris 100.0 162
XP_001504454.1 PREDICTED: s-phase kinase-associated protein 1-like isoform 1 E. caballus 100.0 162
NP_001029953.1 SKP1 gene product B. taurus 100.0 162
NP_001138250.1 SKP1 gene product O. aries 100.0 162
XP_001513378.1 PREDICTED: S-phase kinase-associated protein 1-like, partial O. anatinus 100.0 104
NP_477390.1 skpA, isoform A D. melanogaster 83.3 161
NP_492513.1 Protein SKR-1 C. elegans 81.7 174
XP_001728027.1 conserved hypothetical protein, variant N. crassa 64.9 167
XP_001690964.1 E3 ubiquitin ligase C. reinhardtii 64.7 152
NP_568603.1 S-phase kinase-associated protein 1 A. thaliana 59.4 169
NP_010615.3 Skp1p S. cerevisiae 55.3 189
Other hits (2 of 44) [Show all]SpeciesId(%)Len(aa)
XP_002127692.1 PREDICTED: S-phase kinase-associated protein 1-like C. intestinalis 96.3 161
XP_001634923.1 predicted protein N. vectensis 95.1 161

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; connective tissue; testis; liver; pharynx; pancreas; lung; mixed; blood; muscle; placenta; prostate; kidney; embryonic tissue; uterus; skin; uncharacterized tissue; eye; intestine; bone marrow; salivary gland; vascular; mammary gland; spinal cord; heart; ovary; bone; bladder; adipose tissue; mouth; spleen; tonsil; ganglia; pituitary gland; adrenal gland; lymph node; parathyroid; thymus; cervix; thyroid; esophagus; stomach; lymph; ear; nerve; ascites; umbilical cord; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q31
UniSTS entry: Chr 12 SHGC-5625
UniSTS entry: Chr 12 STS-U37558
UniSTS entry: Chr 5 RH67782
UniSTS entry: Chr 5 WI-13758 [Map Viewer]
UniSTS entry: Chr 5 bac51513T
UniSTS entry: Tceb1l-rs1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_006930.3 Homo sapiens S-phase kinase-associated protein 1 (SKP1), transcript variant 1, mRNA PA
BC065730.1 Homo sapiens S-phase kinase-associated protein 1, mRNA (cDNA clone MGC:72058 IMAGE:6672613), complete cds PA
U33760.1 Human cyclin A/CDK2-associated p19 (Skp1) mRNA, complete cds P
U37558.1 Human RNA polymerase II elongation factor-like protein OCP2 mRNA, partial cds P
BC009839.2 Homo sapiens S-phase kinase-associated protein 1, mRNA (cDNA clone MGC:15226 IMAGE:4053593), complete cds PA
AK057110.1 Homo sapiens cDNA FLJ32548 fis, clone SPLEN1000013 P
BC020798.1 Homo sapiens S-phase kinase-associated protein 1, mRNA (cDNA clone MGC:23780 IMAGE:4243711), complete cds PA
BC025673.1 Homo sapiens S-phase kinase-associated protein 1, mRNA (cDNA clone MGC:34403 IMAGE:5203008), complete cds PA
Z47087.1 H.sapiens mRNA for RNA polymerase II elongation factor-like protein P
NM_170679.2 Homo sapiens S-phase kinase-associated protein 1 (SKP1), transcript variant 2, mRNA PA

EST sequences (10 of 1827) [Show all sequences]

AA922375.1 Clone IMAGE:1474386 intestine 3' read A
AA972630.1 Clone IMAGE:1585040 lung 3' read A
AA974001.1 Clone IMAGE:1586149 uncharacterized tissue 3' read A
R15092.1 Clone IMAGE:25579 brain 3' read A
AA993461.1 Clone IMAGE:1618624 testis 3' read A
AA927664.1 Clone IMAGE:1552675 uncharacterized tissue 3' read PA
AI025746.1 Clone IMAGE:1646528 parathyroid 3' read A
AI028694.1 Clone IMAGE:1644435 testis 3' read A
AI041833.1 Clone IMAGE:1667714 parathyroid 3' read
R19905.1 Clone IMAGE:34917 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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