> SIK family kinase 3 (SIK3)
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UGID:157215     UniGene Hs.167451     Homo sapiens (human)   SIK3
SIK family kinase 3 (SIK3)

Human protein-coding gene SIK3. Represented by 307 ESTs from 152 cDNA libraries. Corresponds to reference sequence NM_025164.3. [UniGene 157215 - Hs.167451]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_079440.2 SIK3 gene product H. sapiens 100.0 1262
XP_508771.3 PREDICTED: hypothetical protein LOC451565 P. troglodytes 100.0 1101
NP_081774.3 Sik3 gene product M. musculus 92.9 1366
NP_956835.1 zgc:66101 gene product D. rerio 70.0 1155
NP_001256565.1 Protein PAR-1, isoform e C. elegans 65.0 329
NP_001084256.1 MAP/microtubule affinity-regulating kinase 3 X. laevis 61.0 423
NP_611359.1 Salt-inducible kinase 3, isoform A D. melanogaster 58.3 564
NP_010765.3 Snf1p S. cerevisiae 52.9 259
XP_958665.2 hypothetical protein NCU04566 N. crassa 50.4 242
NP_198391.1 CBL-interacting serine/threonine-protein kinase 24 A. thaliana 49.2 260
XP_001693723.1 predicted protein C. reinhardtii 45.5 176
Other hits (2 of 63) [Show all]SpeciesId(%)Len(aa)
XP_002799853.1 PREDICTED: serine/threonine-protein kinase SIK3-like M. mulatta 99.1 1103
NP_001162209.1 serine/threonine-protein kinase QSK P. anubis 98.8 922

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; brain; lung; testis; uncharacterized tissue; pancreas; uterus; kidney; mammary gland; lymph node; heart; spleen; liver; larynx; eye; embryonic tissue; vascular; stomach; placenta; pharynx; mouth; intestine; nerve; muscle; blood; connective tissue; prostate; skin; ganglia; bone; amniotic fluid; thyroid; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23.3
UniSTS entry: Chr 11 RH102942
UniSTS entry: Chr 11 WI-19362 [Map Viewer]
UniSTS entry: Chr 11 REN72918
UniSTS entry: Chr 11 REN72865
UniSTS entry: Chr 11 REN72916
UniSTS entry: Chr 11 REN72798
UniSTS entry: Chr 11 REN72866
UniSTS entry: Chr 11 MARC_6495-6496:996689700:1
UniSTS entry: Chr 11 REN72914
UniSTS entry: Chr 11 REN72912
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC063887.1 Homo sapiens KIAA0999 protein, mRNA (cDNA clone IMAGE:30387098), complete cds PA
AY598338.1 Homo sapiens L19 mRNA, complete cds P
BC086858.1 Homo sapiens KIAA0999 protein, mRNA (cDNA clone IMAGE:6500609), partial cds PA
AB209327.1 Homo sapiens mRNA for KIAA0999 protein variant protein P
AK022302.1 Homo sapiens cDNA FLJ12240 fis, clone MAMMA1001271 P
NM_025164.3 Homo sapiens SIK family kinase 3 (SIK3), mRNA P
BC121188.1 Homo sapiens KIAA0999 protein, mRNA (cDNA clone IMAGE:4396995), partial cds PA
BC128510.1 Homo sapiens KIAA0999 protein, mRNA (cDNA clone MGC:156922 IMAGE:40081639), complete cds P
BC128511.1 Homo sapiens KIAA0999 protein, mRNA (cDNA clone MGC:156923 IMAGE:40081640), complete cds P
AL832068.1 Homo sapiens mRNA; cDNA DKFZp313K0618 (from clone DKFZp313K0618) A
BC035583.2 Homo sapiens KIAA0999 protein, mRNA (cDNA clone IMAGE:5583560), partial cds PA

EST sequences (10 of 307) [Show all sequences]

R14613.1 Clone IMAGE:35497 brain 5' read
AI004359.1 Clone IMAGE:1624522 embryonic tissue 3' read A
AI017775.1 Clone IMAGE:1639020 testis 3' read A
AI075147.1 Clone IMAGE:1672902 mixed 3' read A
AI082756.1 Clone IMAGE:1652895 mixed 3' read A
AI138809.1 Clone IMAGE:1737556 testis 3' read A
R23807.1 Clone IMAGE:131655 placenta 5' read
R23981.1 Clone IMAGE:131122 placenta 5' read
BX104866.1 Clone IMAGp998M085809_;_IMAGE:2341423 lung
R26487.1 Clone IMAGE:37470 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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