> Gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1)
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UGID:157172     UniGene Hs.167017     Homo sapiens (human)   GABBR1 Order cDNA clone, Links
Gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1)

Human protein-coding gene GABBR1. Represented by 832 ESTs from 170 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 157172 - Hs.167017]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001461.1 GABBR1 gene product H. sapiens 100.0 960
XP_001097474.2 PREDICTED: gamma-aminobutyric acid type B receptor subunit 1-like M. mulatta 100.0 843
NP_001116586.1 gamma-aminobutyric acid type B receptor subunit 1 precursor S. scrofa 100.0 576
NP_001156747.1 GABBR1 gene product B. taurus 99.9 960
XP_003897323.1 PREDICTED: gamma-aminobutyric acid type B receptor subunit 1 P. anubis 99.9 950
XP_002714384.1 PREDICTED: gamma-aminobutyric acid (GABA) B receptor 1 O. cuniculus 99.8 843
NP_062312.3 Gabbr1 gene product M. musculus 99.7 959
NP_112290.2 Gabbr1 gene product R. norvegicus 99.6 959
XP_004019329.1 PREDICTED: gamma-aminobutyric acid type B receptor subunit 1 O. aries 99.6 937
XP_003200653.1 PREDICTED: gamma-aminobutyric acid type B receptor subunit 1 D. rerio 84.1 969
NP_523569.3 metabotropic GABA-B receptor subtype 1, isoform B D. melanogaster 57.3 785
NP_001256997.1 Protein GBB-1, isoform c C. elegans 53.1 747
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_545462.4 PREDICTED: gamma-aminobutyric acid type B receptor subunit 1 C. lupus familiaris 99.0 890
XP_527324.4 PREDICTED: gamma-aminobutyric acid type B receptor subunit 1 P. troglodytes 98.8 817

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; mammary gland; embryonic tissue; eye; thyroid; nerve; pharynx; ovary; adrenal gland; ganglia; spleen; intestine; uterus; mixed; stomach; bladder; mouth; prostate; lung; testis; liver; kidney; muscle; vascular; epididymis; placenta; connective tissue; heart; larynx; trachea; blood; skin; bone; salivary gland; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.31
UniSTS entry: Chr 6 WI-12368 [Map Viewer]
UniSTS entry: Chr 6 A002D34 [Map Viewer]
UniSTS entry: Chr 6 G19983
UniSTS entry: Chr 6 RH63712 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

BC042598.1 Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1, mRNA (cDNA clone MGC:24911 IMAGE:4938491), complete cds PA
AJ012185.1 Homo sapiens mRNA for GABAB-receptor, subunit 1a P
AJ012186.1 Homo sapiens mRNA for GABAB receptor, subunit 1b P
AJ012187.1 Homo sapiens mRNA for GABAB receptor, subunit 1c P
AJ225028.1 Homo sapiens mRNA for GABA-B R1a receptor PA
AJ225029.1 Homo sapiens mRNA for GABA-B R1b receptor P
AJ012288.1 Homo sapiens mRNA for GABA-BR1 PA
AF099148.1 Homo sapiens GABA-B1a receptor mRNA, complete cds P
BC050532.1 Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1, mRNA (cDNA clone MGC:57575 IMAGE:5732186), complete cds PA
AB208790.1 Homo sapiens mRNA for gamma-aminobutyric acid (GABA) B receptor 1 isoform c precursor variant protein P
AK223619.1 Homo sapiens mRNA for gamma-aminobutyric acid (GABA) B receptor 1 isoform b precursor variant, clone: FCC134B02 P
AF301005.1 Homo sapiens gamma-aminobutyric acid receptor GABA-B1e mRNA, complete cds P
NM_001470.2 Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 1, mRNA PA
NM_021903.2 Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 2, mRNA PA
NM_021904.2 Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 3, mRNA PA
AK290191.1 Homo sapiens cDNA FLJ77697 complete cds, highly similar to Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 2, mRNA P
AK312308.1 Homo sapiens cDNA, FLJ92613, Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1),transcript variant 2, mRNA P
BC023336.1 Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1, mRNA (cDNA clone IMAGE:4934044) PA
BC041332.2 Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1, mRNA (cDNA clone MGC:41792 IMAGE:5275467), complete cds PA
Y11044.1 Homo sapiens mRNA for GABA-BR1a (hGB1a) receptor PA

EST sequences (10 of 832) [Show all sequences]

AA992062.1 Clone IMAGE:1618930 testis 3' read A
AI078526.1 Clone IMAGE:1676694 embryonic tissue 3' read A
AA908707.1 Clone IMAGE:1522173 lung 3' read A
CB054344.1 Clone IMAGE:3291470 brain 3' read A
CB054345.1 Clone IMAGE:3291470 brain 5' read
BX095388.1 Clone IMAGp998K06330 brain 5' read
BX111922.1 Clone IMAGp998F094543_;_IMAGE:1856264 mixed A
BX090421.1 Clone IMAGp998O12673_;_IMAGE:300899 lung
AI202961.1 Clone IMAGE:1942568 uncharacterized tissue 3' read P
AI203251.1 Clone IMAGE:1942289 uncharacterized tissue 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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