> Cubilin (intrinsic factor-cobalamin receptor) (CUBN)
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UGID:157083     UniGene Hs.166206     Homo sapiens (human)   CUBN Links
Cubilin (intrinsic factor-cobalamin receptor) (CUBN)

Human protein-coding gene CUBN. Represented by 130 ESTs from 38 cDNA libraries. Corresponds to reference sequence NM_001081.3. [UniGene 157083 - Hs.166206]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001072.2 CUBN gene product H. sapiens 100.0 3622
NP_001074553.1 cubilin precursor M. musculus 72.8 3622
XP_002666724.2 PREDICTED: cubilin D. rerio 54.7 3625
Other hits (2 of 24) [Show all]SpeciesId(%)Len(aa)
XP_507675.2 PREDICTED: cubilin P. troglodytes 99.1 3621
XP_003919387.1 PREDICTED: cubilin P. anubis 95.8 3608

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: kidney; uncharacterized tissue; testis; brain; intestine; embryonic tissue; placenta; trachea; thyroid; lung; mixed; uterus; thymus; muscle; eye; pancreas; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10p12.31
UniSTS entry: Chr 1 D1S3698
UniSTS entry: Chr 1 D22S296
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF034611.1 Homo sapiens intrinsic factor-B12 receptor precursor, mRNA, complete cds PA
NM_001081.3 Homo sapiens cubilin (intrinsic factor-cobalamin receptor) (CUBN), mRNA P
AB209880.1 Homo sapiens mRNA for cubilin variant protein P
AK308290.1 Homo sapiens cDNA, FLJ98238 P
AK310404.1 Homo sapiens cDNA, FLJ17446 P
AK309623.1 Homo sapiens cDNA, FLJ99664 P
AK075228.1 Homo sapiens cDNA FLJ90747 fis, clone PLACE1011708, highly similar to Cubilin precursor P
AK074536.1 Homo sapiens cDNA FLJ90055 fis, clone HEMBA1003047, highly similar to Cubilin precursor P

EST sequences (10 of 130) [Show all sequences]

AI005054.1 Clone IMAGE:1635189 kidney 3' read P
CB047396.1 Clone IMAGE:3253375 kidney 3' read
CB047397.1 Clone IMAGE:3253375 kidney 5' read P
CB047231.1 Clone IMAGE:3253322 kidney 5' read P
BX090941.1 Clone IMAGp998M054993_;_IMAGE:2029228 kidney P
AI253182.1 Clone IMAGE:2029228 kidney 3' read A
AA910328.1 Clone IMAGE:1520564 kidney 3' read A
AI373743.1 Clone IMAGE:2030694 kidney 3' read A
AI628059.1 Clone IMAGE:2285746 kidney 3' read P
AI744019.1 Clone IMAGE:2316914 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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