> Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (DYRK3)
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UGID:156783     UniGene Hs.164267     Homo sapiens (human)   DYRK3 Order cDNA clone, Links
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (DYRK3)

Human protein-coding gene DYRK3. Represented by 108 ESTs from 52 cDNA libraries. EST representation biased toward fetus. Corresponds to 2 reference sequences (different isoforms). [UniGene 156783 - Hs.164267]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003573.2 DYRK3 gene product H. sapiens 100.0 587
XP_524527.2 PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform 6 P. troglodytes 99.7 587
NP_663483.1 Dyrk3 gene product M. musculus 94.5 585
NP_001088793.1 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 X. laevis 78.3 562
NP_001108400.1 zgc:172180 gene product D. rerio 75.9 576
NP_001033810.1 Dyrk3, isoform A D. melanogaster 71.0 393
NP_001040950.1 Protein MBK-2, isoform d C. elegans 70.7 417
XP_960871.1 hypothetical protein NCU06638 N. crassa 57.5 334
XP_001695011.1 dual-specificity tyrosine regulated protein kinase 1 C. reinhardtii 56.6 356
NP_012394.1 Yak1p S. cerevisiae 53.9 247
NP_001031970.1 YAK1-like protein 1 A. thaliana 48.7 226
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_003893249.1 PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 3 P. anubis 99.5 587
XP_001086117.1 PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform 4 M. mulatta 99.3 587

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; mixed; uncharacterized tissue; cervix; uterus; lung; thymus; eye; spleen; connective tissue; kidney; vascular; heart; ascites; bone; liver; skin
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q32.1
UniSTS entry: Chr 1 G34856
UniSTS entry: Chr 1 NIB1752 [Map Viewer]
UniSTS entry: Chr 1 DYRK3__4798
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_003582.2 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (DYRK3), transcript variant 1, mRNA PA
AY590695.1 Homo sapiens clone IMAGE:5535369 dual-specificity tyrosine-phosphorylation regulated kinase 3 long isoform mRNA, complete cds PA
NM_001004023.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA PA
AF186773.1 Homo sapiens regulatory erythroid kinase long form (RED) mRNA, alternatively spliced product, complete cds P
AF186774.1 Homo sapiens regulatory erythroid kinase short form (RED) mRNA, alternatively spliced product, complete cds P
AF327561.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5 mRNA, complete cds PA
AK291189.1 Homo sapiens cDNA FLJ76189 complete cds, highly similar to Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, mRNA PA
AK308082.1 Homo sapiens cDNA, FLJ98030 P
AK313245.1 Homo sapiens cDNA, FLJ93751, highly similar to Homo sapiens dual-specificity tyrosine-(Y)-phosphorylationregulated kinase 3 (DYRK3), mRNA P
BC037269.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3, mRNA (cDNA clone IMAGE:4822647), complete cds A
BC015501.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3, mRNA (cDNA clone MGC:9059 IMAGE:3913541), complete cds PA
Y12735.2 Homo sapiens mRNA for protein kinase, Dyrk3 P

EST sequences (10 of 108) [Show all sequences]

AA904950.1 Clone IMAGE:1504704 mixed 3' read A
AI095264.1 Clone IMAGE:1666338 skin 3' read PA
AI139874.1 Clone IMAGE:1737461 testis 3' read A
BX103376.1 Clone IMAGp998C095258_;_IMAGE:2130752 kidney A
BX101785.1 Clone IMAGp998A101005_;_IMAGE:428049 mixed P
CB157067.1 Clone L17N670205n1-8-G12 liver 5' read P
CB164274.1 Clone L17N670205n1-29-F11 liver 5' read P
CB127400.1 Clone C1SNU17-19-F02 cervix 5' read P
U69558.1 Clone 23329 brain P
AI289101.1 Clone IMAGE:1991759 uterus 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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