> Thrombospondin 1 (THBS1)
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UGID:156773     UniGene Hs.164226     Homo sapiens (human)   THBS1
Thrombospondin 1 (THBS1)

Human protein-coding gene THBS1. Represented by 1090 ESTs from 324 cDNA libraries. Corresponds to reference sequence NM_003246.2. [UniGene 156773 - Hs.164226]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_510294.3 PREDICTED: thrombospondin-1 isoform 2 P. troglodytes 100.0 1169
NP_003237.2 THBS1 gene product H. sapiens 100.0 1169
XP_001093770.2 PREDICTED: thrombospondin-1 M. mulatta 99.8 1084
XP_003900802.1 PREDICTED: thrombospondin-1 P. anubis 99.7 1169
NP_035710.2 Thbs1 gene product M. musculus 99.6 1170
XP_690395.4 PREDICTED: thrombospondin-1 D. rerio 84.5 1162
NP_001079818.1 thrombospondin 1 precursor X. laevis 79.8 491
NP_001137803.1 thrombospondin, isoform G D. melanogaster 57.7 634
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001503649.1 PREDICTED: thrombospondin-1 E. caballus 99.2 1169
XP_002717845.1 PREDICTED: thrombospondin 1 O. cuniculus 99.0 1170

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; mammary gland; liver; embryonic tissue; skin; vascular; kidney; bone; brain; mixed; esophagus; intestine; uterus; connective tissue; placenta; pancreas; muscle; uncharacterized tissue; prostate; ovary; stomach; bone marrow; thyroid; eye; blood; mouth; umbilical cord; larynx; amniotic fluid; testis; cervix; bladder; adrenal gland; spleen; trachea; heart; salivary gland; ear; nerve; thymus; pharynx; adipose tissue; epididymis; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q15
UniSTS entry: Chr 15 RH77893 [Map Viewer]
UniSTS entry: Chr 15 THBS1
UniSTS entry: Chr 15 D15S1164 [Map Viewer]
UniSTS entry: Chr 15 6STS01
UniSTS entry: Chr 15 TCF12
UniSTS entry: Chr 15 RH70562
UniSTS entry: M87276
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

M99425.1 Human thrombospondin mRNA, 3' end P
NM_003246.2 Homo sapiens thrombospondin 1 (THBS1), mRNA PA
AB209912.1 Homo sapiens mRNA for thrombospondin 1 precursor variant protein P
M14326.1 Human thrombospondin (TSP) mRNA, 5' end P
X04665.1 Human mRNA for thrombospondin P
X14787.1 Human mRNA for thrombospondin P
AK291639.1 Homo sapiens cDNA FLJ76873 complete cds, highly similar to Homo sapiens thrombospondin 1 (THBS1), mRNA P
AK310820.1 Homo sapiens cDNA, FLJ17862 P
AK309613.1 Homo sapiens cDNA, FLJ99654
AK293230.1 Homo sapiens cDNA FLJ52119 complete cds P
AK304754.1 Homo sapiens cDNA FLJ51203 complete cds, highly similar to Thrombospondin-1 precursor P
BC028145.1 Homo sapiens thrombospondin 1, mRNA (cDNA clone IMAGE:5217975), partial cds P
M25631.1 Homo sapiens (clone lambda-TS-33) thrombospondin (THBS) mRNA, 5' end P
BC136470.1 Homo sapiens thrombospondin 1, mRNA (cDNA clone MGC:168082 IMAGE:9020459), complete cds P
BC136469.1 Homo sapiens thrombospondin 1, mRNA (cDNA clone MGC:168081 IMAGE:9020458), complete cds P

EST sequences (10 of 1090) [Show all sequences]

AA947542.1 Clone IMAGE:1374901 ovary
AA999989.1 Clone IMAGE:1636537 kidney 3' read
AI000621.1 Clone IMAGE:1609242 mammary gland 3' read P
AI000849.1 Clone IMAGE:1609381 mammary gland 3' read P
AI002688.1 Clone IMAGE:1699181 kidney 3' read A
AI003785.1 Clone IMAGE:1635230 kidney 3' read P
AI041974.1 Clone IMAGE:1665475 skin 3' read P
AI042554.1 Clone IMAGE:1665076 skin 3' read P
AI077756.1 Clone IMAGE:1664113 skin 3' read A
AI080581.1 Clone IMAGE:1680411 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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