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UGID:133567     UniGene Hs.16355     Homo sapiens (human)   MYH10
Myosin, heavy chain 10, non-muscle (MYH10)

Human protein-coding gene MYH10. Represented by 540 ESTs from 232 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 133567 - Hs.16355]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001242941.1 MYH10 gene product H. sapiens 100.0 2006
XP_001166541.2 PREDICTED: myosin-10 isoform 7 P. troglodytes 100.0 1984
XP_003912370.1 PREDICTED: myosin-10 isoform 3 P. anubis 100.0 2006
XP_001504875.1 PREDICTED: myosin-10 isoform 1 E. caballus 99.9 1975
XP_001118181.2 PREDICTED: myosin-10 M. mulatta 99.8 1998
XP_003483154.1 PREDICTED: myosin-10, partial S. scrofa 99.7 1860
NP_777259.1 MYH10 gene product B. taurus 99.7 1975
XP_004012739.1 PREDICTED: myosin-10 isoform 2 O. aries 99.6 1984
NP_780469.1 Myh10 gene product M. musculus 99.6 1975
XP_002719031.1 PREDICTED: myosin heavy chain O. cuniculus 99.5 1975
XP_003639100.1 PREDICTED: myosin-10 C. lupus familiaris 99.5 1984
XP_683046.5 PREDICTED: myosin-10 D. rerio 93.8 1976
NP_001084034.1 myosin, heavy chain 10, non-muscle X. laevis 93.6 1985
NP_001189008.1 zipper, isoform E D. melanogaster 70.6 1938
NP_508504.2 Protein NMY-1 C. elegans 61.7 1943
XP_964712.2 hypothetical protein NCU00551 N. crassa 58.8 867
NP_011888.1 myosin 1 S. cerevisiae 53.6 830
XP_001693409.1 myosin heavy chain C. reinhardtii 45.7 186
NP_001154724.1 Myosin family protein with Dil domain A. thaliana 45.6 523
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
NP_113708.1 Myh10 gene product R. norvegicus 99.4 1975
XP_003340371.1 PREDICTED: LOW QUALITY PROTEIN: myosin-10-like M. domestica 98.0 1979

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; brain; eye; adipose tissue; mixed; uterus; heart; skin; lung; adrenal gland; mouth; testis; placenta; mammary gland; uncharacterized tissue; ovary; kidney; pituitary gland; bone; thyroid; prostate; pancreas; blood; muscle; umbilical cord; intestine; stomach; ear; vascular; epididymis; lymph; bladder; connective tissue; amniotic fluid; liver; parathyroid; trachea; larynx; nerve; thymus; esophagus; pineal gland; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13
UniSTS entry: Chr 17 RH93338
UniSTS entry: Chr 17 RH18038
UniSTS entry: Chr 17 SHGC-32450 [Map Viewer]
UniSTS entry: Chr 17 SHGC-12899 [Map Viewer]
UniSTS entry: Chr 17 MARC_24284-24285:1030045561:1
UniSTS entry: Chr 17 MYH10_2175
UniSTS entry: RH98270
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

NM_005964.3 Homo sapiens myosin, heavy chain 10, non-muscle (MYH10), transcript variant 2, mRNA PA
AB210026.1 Homo sapiens mRNA for MYH10 variant protein, partial cds, clone: hf00991 P
AK026977.1 Homo sapiens cDNA: FLJ23324 fis, clone HEP12482, highly similar to HUMMYOHCB Human nonmuscle myosin heavy chain-B (MYH10) mRNA PA
BC000280.1 Homo sapiens myosin, heavy chain 10, non-muscle, mRNA (cDNA clone IMAGE:3357927), partial cds PA
BC117691.1 Homo sapiens myosin, heavy chain 10, non-muscle, mRNA (cDNA clone MGC:134914 IMAGE:40072061), complete cds P
BC117690.1 Homo sapiens myosin, heavy chain 10, non-muscle, mRNA (cDNA clone MGC:134913 IMAGE:40072059), complete cds P
DQ925667.1 Homo sapiens clone 1-3 nonmuscle myosin heavy chain 10 (MYH10) mRNA, partial cds, alternatively spliced P
BC150634.1 Homo sapiens myosin, heavy chain 10, non-muscle, mRNA (cDNA clone MGC:183544 IMAGE:9057004), complete cds P
U34304.1 Human nonmuscle myosin heavy chain IIB mRNA, partial cds P
BC008968.2 Homo sapiens myosin, heavy chain 10, non-muscle, mRNA (cDNA clone IMAGE:3028454), partial cds PA
AF086505.1 Homo sapiens full length insert cDNA clone ZE02D01
M69181.1 Human nonmuscle myosin heavy chain-B (MYH10) mRNA, partial cds PA
U15618.1 Human nonmuscle myosin heavy chain-B mRNA, partial cds P
BC144668.1 Homo sapiens myosin, heavy chain 10, non-muscle, mRNA (cDNA clone MGC:178216 IMAGE:9053199), complete cds P
S67247.1 smooth muscle myosin heavy chain isoform SMemb [human, umbilical cord, fetal aorta, mRNA Partial, 971 nt] P
AB621820.1 Homo sapiens MYH10 mRNA for myosin-10, partial cds, clone: HP08316-RBdS007C12 P
NM_001256012.1 Homo sapiens myosin, heavy chain 10, non-muscle (MYH10), transcript variant 1, mRNA PA
NM_001256095.1 Homo sapiens myosin, heavy chain 10, non-muscle (MYH10), transcript variant 3, mRNA PA

EST sequences (10 of 540) [Show all sequences]

AA983970.1 Clone IMAGE:1601073 uncharacterized tissue 3' read
R16384.1 Clone IMAGE:29724 brain 5' read
AA993349.1 Clone IMAGE:1621523 testis 3' read A
AI004136.1 Clone IMAGE:1619572 testis 3' read A
AI038907.1 Clone IMAGE:1664200 skin 3' read
T06000.1 Clone HFBDK82 brain P
AI055902.1 Clone IMAGE:1648366 parathyroid 3' read A
AI094099.1 Clone IMAGE:1688597 mixed 3' read P
AI123277.1 Clone IMAGE:1640532 testis 3' read A
AI123565.1 Clone IMAGE:1690158 mixed 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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