> Solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2)
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UGID:156406     UniGene Hs.162585     Homo sapiens (human)   SLC12A2 Order cDNA clone, Links
Solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2)

Human protein-coding gene SLC12A2. Represented by 252 ESTs from 159 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 156406 - Hs.162585]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001037.1 SLC12A2 gene product H. sapiens 100.0 1211
XP_526998.2 PREDICTED: solute carrier family 12 member 2 isoform 2 P. troglodytes 99.8 1210
NP_001248714.1 solute carrier family 12 member 2 M. mulatta 99.8 1209
NP_033220.2 Slc12a2 gene product M. musculus 97.6 1205
NP_001091331.1 Na-K-2Cl cotransporter 1 X. laevis 89.9 1134
NP_001002080.1 slc12a2 gene product D. rerio 81.5 1130
NP_648572.1 sodium chloride cotransporter 69, isoform A D. melanogaster 58.4 1153
NP_502704.1 Protein NKCC-1, isoform a C. elegans 55.7 808
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_538611.4 PREDICTED: solute carrier family 12 member 2, partial C. lupus familiaris 98.6 1117
XP_003123947.1 PREDICTED: solute carrier family 12 member 2 S. scrofa 98.3 1201

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; brain; testis; prostate; mammary gland; pharynx; lung; ear; uncharacterized tissue; kidney; larynx; bone marrow; lymph node; adrenal gland; salivary gland; thyroid; mouth; trachea; embryonic tissue; stomach; liver; eye; mixed; uterus; cervix; muscle; ovary; skin; heart; thymus; bladder; spinal cord; placenta; pancreas; blood; ascites; connective tissue; vascular; parathyroid; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q23.3
UniSTS entry: Chr 5 STS-N22107
UniSTS entry: Chr 5 SGC35509 [Map Viewer]
UniSTS entry: Chr 5 A006Y26
UniSTS entry: Chr 5 SGC32885 [Map Viewer]
UniSTS entry: Chr 5 bac51423S
UniSTS entry: Chr 1 D10S275
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AY280459.1 Homo sapiens bumetanide-sensitive Na-K-Cl cotransporter (SLC12A2) mRNA, complete cds P
NM_001046.2 Homo sapiens solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2), transcript variant 1, mRNA PA
AB209192.1 Homo sapiens mRNA for solute carrier family 12 (sodium/potassium/chloride transporters), member 2 variant protein P
AK025062.1 Homo sapiens cDNA: FLJ21409 fis, clone COL03924 A
AF439152.1 Homo sapiens sodium-potassium-chloride cotransporter (SLC12A2) mRNA, partial cds, alternatively spliced P
Z36839.1 H.sapiens (xs81) mRNA, 289bp
M18217.1 Human DNA of undetermined origin found 5' to NCA mRNA
BC144221.1 Homo sapiens solute carrier family 12 (sodium/potassium/chloride transporters), member 2, mRNA (cDNA clone MGC:177758 IMAGE:9052741), complete cds P
BC146839.1 Homo sapiens solute carrier family 12 (sodium/potassium/chloride transporters), member 2, mRNA (cDNA clone MGC:181942 IMAGE:9056767), complete cds P
NM_001256461.1 Homo sapiens solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2), transcript variant 2, mRNA PA
NR_046207.1 Homo sapiens solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2), transcript variant 3, non-coding RNA PA
U30246.1 Human bumetanide-sensitive Na-K-Cl cotransporter (NKCC1) mRNA, complete cds P

EST sequences (10 of 252) [Show all sequences]

AI014857.1 Clone IMAGE:1622097 embryonic tissue 3' read A
AI078667.1 Clone IMAGE:1667919 parathyroid 3' read A
AI096401.1 Clone IMAGE:1707507 heart 3' read
AI096403.1 Clone IMAGE:1707511 heart 3' read
AI124709.1 Clone IMAGE:1540026 brain 3' read P
BX098657.1 Clone IMAGp998L215321_;_IMAGE:2155172 intestine A
BX106574.1 Clone IMAGp998M234417 testis 5' read P
AI187969.1 Clone IMAGE:1738558 testis 3' read A
CB146321.1 Clone L16HLK3-26-D07 liver 5' read P
CB158589.1 Clone L18POOL1n1-12-A05 liver 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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