> Deleted in colorectal carcinoma (DCC)
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UGID:156181     UniGene Hs.162025     Homo sapiens (human)   DCC
Deleted in colorectal carcinoma (DCC)

Human protein-coding gene DCC. Represented by 70 ESTs from 27 cDNA libraries. Corresponds to reference sequence NM_005215.3. [UniGene 156181 - Hs.162025]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005206.2 DCC gene product H. sapiens 100.0 1446
XP_512137.2 PREDICTED: netrin receptor DCC P. troglodytes 99.9 1446
XP_003914440.1 PREDICTED: netrin receptor DCC-like P. anubis 99.5 809
NP_031857.2 Dcc gene product M. musculus 97.4 1446
NP_001079254.1 deleted in colorectal carcinoma X. laevis 85.0 1426
NP_001030157.1 dcc gene product D. rerio 75.6 1413
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_002800982.1 PREDICTED: netrin receptor DCC-like M. mulatta 98.8 1396
XP_003121496.3 PREDICTED: netrin receptor DCC-like, partial S. scrofa 98.3 809

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; mixed; brain; uncharacterized tissue; bone; esophagus; thymus; connective tissue; lung; embryonic tissue; ear; kidney
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21.3
UniSTS entry: Chr 18 GDB:201899
UniSTS entry: Chr 18 GDB:201900
UniSTS entry: Chr 18 GDB:201895
UniSTS entry: Chr 18 GDB:201896
UniSTS entry: Chr 18 GDB:201919
UniSTS entry: Chr 18 GDB:201897
UniSTS entry: Chr 18 GDB:201902
UniSTS entry: Chr 18 GDB:201903
UniSTS entry: Chr 18 GDB:201904
UniSTS entry: Chr 18 GDB:201909
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_005215.3 Homo sapiens deleted in colorectal carcinoma (DCC), mRNA PA
BC036524.1 Homo sapiens deleted in colorectal carcinoma, mRNA (cDNA clone IMAGE:4837261), partial cds PA
AK310385.1 Homo sapiens cDNA, FLJ17427 P
X76132.1 H.sapiens DCC mRNA P
AK302643.1 Homo sapiens cDNA FLJ51404 complete cds, highly similar to Netrin receptor DCC precursor PA
S81335.1 DCC=deleted in colorectal cancer {alternatively spliced, exon 28A} [human, brain tumor, tumor no. 245, mRNA Partial, 165 nt]
M32292.1 Human colorectal tumor suppressor mRNA (DCC), 5' end P

EST sequences (10 of 70) [Show all sequences]

AA976364.1 Clone IMAGE:1591484 kidney 3' read
AA904417.1 Clone IMAGE:1507144 mixed 3' read
AA907540.1 Clone IMAGE:1540499 mixed 3' read P
AI124557.1 Clone IMAGE:1539794 brain 3' read
BX102517.1 Clone IMAGp998M115814_;_IMAGE:2343346 lung A
BX101501.1 Clone IMAGp998P052575_;_IMAGE:1031284 testis A
AI377843.1 Clone IMAGE:2091389 mixed 3' read P
AI425016.1 Clone IMAGE:2112204 mixed 3' read A
AI650724.1 Clone IMAGE:2306751 uncharacterized tissue 3' read A
AI677901.1 Clone IMAGE:2330072 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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