> Insulin-like growth factor 1 (somatomedin C) (IGF1)
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UGID:155852     UniGene Hs.160562     Homo sapiens (human)   IGF1 Order cDNA clone, Links
Insulin-like growth factor 1 (somatomedin C) (IGF1)

Human protein-coding gene IGF1. Represented by 222 ESTs from 108 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 155852 - Hs.160562]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001104755.1 IGF1 gene product H. sapiens 100.0 194
XP_003907101.1 PREDICTED: insulin-like growth factor I isoform 3 P. anubis 100.0 158
XP_001156345.1 PREDICTED: insulin-like growth factor I isoform 1 P. troglodytes 100.0 158
XP_001094251.1 PREDICTED: insulin-like growth factor 1 isoform 4 M. mulatta 100.0 152
NP_001104745.1 Igf1 gene product M. musculus 93.5 152
NP_001156865.1 insulin-like growth factor I-A precursor X. laevis 79.1 152
NP_571900.1 igf1 gene product D. rerio 68.4 154
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
NP_001075967.2 IGF1 gene product E. caballus 99.3 152
XP_853117.1 PREDICTED: insulin-like growth factor I isoform 2 C. lupus familiaris 98.0 152

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: prostate; mixed; liver; uterus; ovary; ear; embryonic tissue; kidney; heart; uncharacterized tissue; pharynx; muscle; placenta; connective tissue; eye; pancreas; intestine; brain; esophagus; nerve; trachea; salivary gland; lung; testis; lymph node; mammary gland; stomach; vascular; blood; larynx; parathyroid; adrenal gland; bone; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q23.2
UniSTS entry: Chr 12 D12S1962
UniSTS entry: RH18058
UniSTS entry: Chr 12 RH77802 [Map Viewer]
UniSTS entry: Igf1
UniSTS entry: Igf1
UniSTS entry: Chr 12 GDB:384821
UniSTS entry: Chr 12 G10727
UniSTS entry: Chr 12 WI-18971 [Map Viewer]
UniSTS entry: Chr 12 WI-21639 [Map Viewer]
UniSTS entry: Chr X SHGC-31984 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

X00173.1 Homo sapiens mRNA for insulin-like growth factor 1A precursor, complete CDS P
CR541861.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0732D for gene IGF1, insulin-like growth factor 1 (somatomedin C); complete cds, incl. stopcodon P
M11568.1 Human insulin-like growth factor IB (IGF-IB) cDNA to mRNA P
M29644.1 Human insulin-like growth factor I mRNA, complete cds P
M27544.1 Human insulin-like growth factor mRNA, complete cds P
M37484.1 Human insulin-like growth factor I (IGF-I) mRNA, complete cds P
AB209184.1 Homo sapiens mRNA for insulin-like growth factor 1 (somatomedin C); insulin-like growth factor 1 (somatomedia C) variant protein PA
NM_000618.3 Homo sapiens insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 4, mRNA P
BC152321.1 Homo sapiens insulin-like growth factor 1 (somatomedin C), mRNA (cDNA clone MGC:157712 IMAGE:40129266), complete cds P
NM_001111285.1 Homo sapiens insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 3, mRNA P
NM_001111284.1 Homo sapiens insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 2, mRNA P
NM_001111283.1 Homo sapiens insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 1, mRNA P
AK312231.1 Homo sapiens cDNA, FLJ92522, Homo sapiens insulin-like growth factor 1 (somatomedin C) (IGF1),mRNA P
BC148266.1 Homo sapiens insulin-like growth factor 1 (somatomedin C), mRNA (cDNA clone MGC:166952 IMAGE:8860206), complete cds P
X56773.1 H.sapiens mRNA for IGF-1a P
X56774.1 H.sapiens mRNA for IGF-1b P
X57025.1 Human IGF-I mRNA for insulin-like growth factor I PA
U40870.1 Human alternatively spliced human insulin-like growth factor-I (IGF-I) mRNA, partial cds P
JX088243.1 Homo sapiens long intergenic non-protein coding RNA, complete sequence A

EST sequences (10 of 222) [Show all sequences]

AA954497.1 Clone IMAGE:1563074 mixed 3' read
AA993659.1 Clone IMAGE:1623620 embryonic tissue 3' read P
AA904407.1 Clone IMAGE:1507109 mixed 3' read
AI033043.1 Clone IMAGE:1654390 mixed 3' read
AI040715.1 Clone IMAGE:1657438 embryonic tissue 3' read A
R21202.1 Clone IMAGE:130330 placenta 5' read
AI093775.1 Clone IMAGE:1688436 mixed 3' read
R22816.1 Clone IMAGE:130330 placenta 3' read
CB156992.1 Clone L17N670205n1-6-G03 liver 5' read P
CB162379.1 Clone L17N670205n1-14-A08 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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