Hepatocellular carcinoma, down-regulated 1 (HEPN1)

Restricted Expression:

glioma [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

brain; mammary gland; muscle; uncharacterized tissue; eye; nerve

NCBI

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Finding cDNAs

UGID:155752 UniGene Hs.159863 Homo sapiens (human) HEPN1

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Hepatocellular carcinoma, down-regulated 1 (HEPN1)

Human protein-coding gene HEPN1. Represented by 46 ESTs from 25 cDNA libraries. EST representation biased toward glioma. Corresponds to reference sequence NM_001037558.2. [UniGene 155752 - Hs.159863]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001032647.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	HEPN1 gene product	H. sapiens	100.0	87
Other hits (		Species	Id(%)	Len(aa)
XP_003952107.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: putative cancer susceptibility gene HEPN1 protein	P. troglodytes	98.9	87

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	11
Map position:	11q24
UniSTS entry:	Chr 11	RH78168

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

	AY275431.1	Homo sapiens cancer susceptibility gene mRNA, complete cds	P
	NM_001037558.2	Homo sapiens hepatocellular carcinoma, down-regulated 1 (HEPN1), mRNA	P

EST sequences (10 of 46) [Show all sequences]

R48182.1	Clone IMAGE:153765	mammary gland	5' read
R48490.1	Clone IMAGE:153857	mammary gland	5' read
F27109.1	Clone s4000065D04	muscle
F35813.1	Clone sH5-000011-0/H01	muscle
AI885128.1	Clone IMAGE:2432154	brain	3' read
BX452118.2	Clone CS0DF024YI23	brain	5' read	P
CF455670.1	Clone IMAGE:30515953	nerve	5' read	P
R74146.1	Clone IMAGE:156898	mammary gland	5' read
H30684.1	Clone IMAGE:184021	brain	5' read
BE701223.1		brain

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria