> V-raf-1 murine leukemia viral oncogene homolog 1 (RAF1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:155566     UniGene Hs.159130     Homo sapiens (human)   RAF1 Order cDNA clone, Links
V-raf-1 murine leukemia viral oncogene homolog 1 (RAF1)

Human protein-coding gene RAF1. Represented by 928 ESTs from 342 cDNA libraries. Corresponds to reference sequence NM_002880.3. [UniGene 155566 - Hs.159130]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001086154.1 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 2 M. mulatta 100.0 647
XP_003894122.1 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 1 P. anubis 100.0 647
XP_516289.2 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 6 P. troglodytes 100.0 647
NP_002871.1 RAF1 gene product H. sapiens 100.0 647
XP_001492290.1 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 1 E. caballus 100.0 647
XP_859234.1 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 4 C. lupus familiaris 99.7 647
XP_002713090.1 PREDICTED: v-raf-1 murine leukemia viral oncogene homolog 1 O. cuniculus 99.7 647
NP_084056.1 Raf1 gene product M. musculus 99.1 647
NP_001081475.1 RAF proto-oncogene serine/threonine-protein kinase X. laevis 92.2 637
NP_001186684.1 RAF proto-oncogene serine/threonine-protein kinase D. rerio 87.5 622
NP_525047.1 pole hole, isoform A D. melanogaster 63.9 596
NP_741430.3 Protein LIN-45, isoform a C. elegans 62.5 395
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
NP_036771.1 Raf1 gene product R. norvegicus 99.4 647
XP_004018591.1 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 1 O. aries 99.4 647

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; skin; mixed; embryonic tissue; uncharacterized tissue; thymus; placenta; blood; bone marrow; adipose tissue; uterus; lymph node; ovary; umbilical cord; prostate; intestine; spinal cord; trachea; amniotic fluid; eye; pancreas; kidney; vascular; adrenal gland; mouth; stomach; liver; ear; connective tissue; heart; mammary gland; ascites; cervix; bone; larynx; muscle; lymph; pineal gland; thyroid; nerve; esophagus; spleen; ganglia; parathyroid; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p25
UniSTS entry: Chr 3 G15882
UniSTS entry: Chr 3 A009W45
UniSTS entry: Chr 3 G32929
UniSTS entry: Chr 3 GDB:217154
UniSTS entry: Chr 3 D3S4000
UniSTS entry: Chr 3 SHGC-57030
UniSTS entry: Chr 15 PZD00074_allele_9942870
UniSTS entry: Chr 3 STS-N27641 [Map Viewer]
UniSTS entry: Chr 3 GDB:181223
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BX648063.1 Homo sapiens mRNA; cDNA DKFZp686J20203 (from clone DKFZp686J20203) P
AK124449.1 Homo sapiens cDNA FLJ42458 fis, clone BRACE2018727
NM_002880.3 Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1), mRNA PA
AK226028.1 Homo sapiens mRNA for v-raf-1 murine leukemia viral oncogene homolog 1 variant, clone: FCC104F09 PA
AK055589.1 Homo sapiens cDNA FLJ31027 fis, clone HLUNG2000557
BC018119.2 Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1, mRNA (cDNA clone MGC:9026 IMAGE:3904404), complete cds PA
AK312248.1 Homo sapiens cDNA, FLJ92543, highly similar to Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1(RAF1), mRNA P
AK303920.1 Homo sapiens cDNA FLJ50355 complete cds, highly similar to RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) P
AK303561.1 Homo sapiens cDNA FLJ57286 complete cds, highly similar to RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) P
X03484.1 Human mRNA for raf oncogene P
FM209427.1 Homo sapiens mRNA for SRGAP3:RAF1 fusion protein (SRGAP3:RAF1 gene) P
GU149302.1 Homo sapiens ESRP1/RAF1 fusion protein mRNA, complete cds P

EST sequences (10 of 928) [Show all sequences]

AA908280.1 Clone IMAGE:1441655 mammary gland 3' read
AA969308.1 Clone IMAGE:1580449 mixed 3' read
AA970685.1 Clone IMAGE:1579030 mixed 3' read A
AA973518.1 Clone IMAGE:1569212 lung 3' read
AA989206.1 Clone IMAGE:1601844 lung 3' read
AA991510.1 Clone IMAGE:1609636 mammary gland 3' read
AA993816.1 Clone IMAGE:1624350 embryonic tissue 5' read
AI003644.1 Clone IMAGE:392010 pineal gland 3' read A
AA927871.1 Clone IMAGE:1541359 mixed 3' read A
R17886.1 Clone IMAGE:31799 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help