> PRP4 pre-mRNA processing factor 4 homolog B (yeast) (PRPF4B)
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UGID:155517     UniGene Hs.159014     Homo sapiens (human)   PRPF4B Order cDNA clone, Links
PRP4 pre-mRNA processing factor 4 homolog B (yeast) (PRPF4B)

Human protein-coding gene PRPF4B. Represented by 476 ESTs from 218 cDNA libraries. Corresponds to reference sequence NM_003913.4. [UniGene 155517 - Hs.159014]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_518214.3 PREDICTED: serine/threonine-protein kinase PRP4 homolog P. troglodytes 100.0 1006
NP_003904.3 PRPF4B gene product H. sapiens 100.0 1006
XP_001094163.1 PREDICTED: serine/threonine-protein kinase PRP4 homolog M. mulatta 99.8 1006
XP_003897054.1 PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase PRP4 homolog P. anubis 99.6 1047
NP_038858.2 Prpf4b gene product M. musculus 98.4 1006
NP_001088314.1 PRP4 pre-mRNA processing factor 4 homolog B X. laevis 90.0 990
NP_998614.1 prpf4bb gene product D. rerio 83.6 973
NP_612010.1 CG7028, isoform A D. melanogaster 72.7 553
NP_492008.1 vertebrate Pre-mRNA Processing Factor family member (prpf-4) C. elegans 61.1 619
XP_001696438.1 protein kinase C. reinhardtii 57.9 356
NP_190932.1 protein kinase family protein A. thaliana 57.7 479
XP_001728078.1 hypothetical protein NCU10853 N. crassa 56.6 380
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_003356557.2 PREDICTED: serine/threonine-protein kinase PRP4 homolog S. scrofa 99.3 599
XP_001489270.3 PREDICTED: serine/threonine-protein kinase PRP4 homolog E. caballus 99.2 1040

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; mammary gland; ovary; spleen; thymus; heart; ear; lung; placenta; liver; mixed; embryonic tissue; kidney; pancreas; vascular; uterus; eye; intestine; bladder; bone marrow; lymph; thyroid; skin; trachea; prostate; mouth; stomach; lymph node; blood; connective tissue; muscle; bone; pharynx; parathyroid; esophagus; adipose tissue; cervix; nerve; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p25.2
UniSTS entry: Chr 6 D6S1932 [Map Viewer]
UniSTS entry: Chr 6 PRP4
UniSTS entry: Chr 6 STS-N39448
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_003913.4 Homo sapiens PRP4 pre-mRNA processing factor 4 homolog B (yeast) (PRPF4B), mRNA P
AY029347.1 Homo sapiens serine/threonine-protein kinase (PRP4) mRNA, complete cds P
AK291244.1 Homo sapiens cDNA FLJ76831 complete cds, highly similar to Homo sapiens PRP4 pre-mRNA processing factor 4 homolog B (yeast) (PRPF4B), transcript variant 1, mRNA P
U48736.1 Human serine/threonine-protein kinase PRP4h (PRP4h) mRNA, complete cds P
AK303047.1 Homo sapiens cDNA FLJ51417 complete cds, highly similar to Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) P
BC009844.2 Homo sapiens PRP4 pre-mRNA processing factor 4 homolog B (yeast), mRNA (cDNA clone IMAGE:3943395), complete cds PA
Z25435.1 H.sapiens protein-serine/threonine kinase gene, complete CDS
BC034969.1 Homo sapiens PRP4 pre-mRNA processing factor 4 homolog B (yeast), mRNA (cDNA clone MGC:26845 IMAGE:4821304), complete cds PA

EST sequences (10 of 476) [Show all sequences]

AA954720.1 Clone IMAGE:1572880 kidney 3' read A
R16159.1 Clone IMAGE:53267 brain 3' read A
R15417.1 Clone IMAGE:53267 brain 5' read
AA988492.1 Clone IMAGE:1603013 lung 3' read
AI015581.1 Clone IMAGE:1636848 kidney 3' read A
AI032816.1 Clone IMAGE:1656618 mixed 3' read A
AI032886.1 Clone IMAGE:1646745 parathyroid 3' read A
AI078056.1 Clone IMAGE:1675186 mixed 3' read
T06372.1 Clone HFBDS56 brain
AI216759.1 Clone IMAGE:1884521 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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