CD244 molecule, natural killer cell receptor 2B4 (CD244)

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UGID:155189 UniGene Hs.157872 Homo sapiens (human) CD244

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CD244 molecule, natural killer cell receptor 2B4 (CD244)

Human protein-coding gene CD244. Represented by 34 ESTs from 23 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 155189 - Hs.157872]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001160135.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CD244 gene product	H. sapiens	100.0	369
NP_061199.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Cd244 gene product	M. musculus	49.1	396
Other hits (2 of 10) [Show all]		Species	Id(%)	Len(aa)
XP_513927.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: natural killer cell receptor 2B4	P. troglodytes	92.0	422
XP_001117630.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: natural killer cell receptor 2B4-like isoform 2	M. mulatta	90.9	349

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; spleen; blood; uterus; intestine; testis; uncharacterized tissue; mixed; thymus; liver; connective tissue; placenta

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	1
	Map position:	1q23.3

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BC053985.1	Homo sapiens CD244 molecule, natural killer cell receptor 2B4, mRNA (cDNA clone MGC:59768 IMAGE:5484877), complete cds	PA
BC028073.1	Homo sapiens CD244 molecule, natural killer cell receptor 2B4, mRNA (cDNA clone MGC:39928 IMAGE:5213370), complete cds	PA
NM_016382.3	Homo sapiens CD244 molecule, natural killer cell receptor 2B4 (CD244), transcript variant 1, mRNA	PA
AJ245375.1	Homo sapiens mRNA for PP35 act (h2B4 gene)	P
AJ245376.1	Homo sapiens mRNA for h2B4b act (h2B4 gene)	P
AF105261.1	Homo sapiens natural killer cell receptor 2B4 mRNA, complete cds	PA
AF107761.2	Homo sapiens NK cell receptor (2B4) mRNA, complete cds	P
AF145782.1	Homo sapiens 2B4 type I transmembrane protein mRNA, complete cds	PA
AF117711.1	Homo sapiens NK cell activation inducing ligand NAIL mRNA, complete cds	P
AF242540.1	Homo sapiens NK cell type I receptor protein 2B4 (2B4) mRNA, complete cds, alternatively spliced	PA
AK313201.1	Homo sapiens cDNA, FLJ93700, highly similar to Homo sapiens CD244 natural killer cell receptor 2B4 (CD244), mRNA	P
AK295950.1	Homo sapiens cDNA FLJ58384 complete cds, highly similar to Natural killer cell receptor 2B4 precursor	P
AF363452.1	Homo sapiens NK cell type I receptor protein 2B4 (CD244) mRNA, partial cds, alternatively spliced	P
NM_001166664.1	Homo sapiens CD244 molecule, natural killer cell receptor 2B4 (CD244), transcript variant 3, mRNA	PA
NM_001166663.1	Homo sapiens CD244 molecule, natural killer cell receptor 2B4 (CD244), transcript variant 2, mRNA	PA
BC041607.1	Homo sapiens CD244 molecule, natural killer cell receptor 2B4, mRNA (cDNA clone IMAGE:5483828)	PA

EST sequences (10 of 34) [Show all sequences]

AI363168.1	Clone IMAGE:2015920	brain	3' read	A
CB217129.1	Clone IMAGE:5938723	uterus	5' read
AI572267.1	Clone IMAGE:2089045	mixed	3' read	A
AI688606.1	Clone IMAGE:2325935	intestine	3' read	A
BX281209.1	Clone IMAGp998L118313_;_IMAGE:3406234	brain		P
AI871467.1	Clone IMAGE:2429965	brain	3' read
AW452231.1	Clone IMAGE:3068098	uncharacterized tissue	3' read	A
AW513657.1	Clone IMAGE:2737826	intestine	3' read
BP340181.1	Clone SPL08252	spleen	5' read
DA463231.1	Clone D3OST2000692	uncharacterized tissue	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria