> Cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1)
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UGID:154387     UniGene Hs.154654     Homo sapiens (human)   CYP1B1 Order cDNA clone, Links
Cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1)

Human protein-coding gene CYP1B1. Represented by 618 ESTs from 200 cDNA libraries. Corresponds to reference sequence NM_000104.3. [UniGene 154387 - Hs.154654]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000095.2 CYP1B1 gene product H. sapiens 100.0 542
NP_034124.1 Cyp1b1 gene product M. musculus 85.1 542
NP_001139180.1 cyp1b1 gene product D. rerio 61.4 505
NP_001090541.1 cytochrome P450, family 1, subfamily A, polypeptide 1 X. laevis 47.4 211
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_001167556.1 PREDICTED: cytochrome P450 1B1-like isoform 1 P. troglodytes 99.5 542
XP_001109361.1 PREDICTED: cytochrome P450 1B1-like isoform 2 M. mulatta 95.9 541

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; brain; lung; uncharacterized tissue; skin; mixed; testis; kidney; eye; mammary gland; uterus; spleen; bone marrow; mouth; trachea; prostate; esophagus; thymus; liver; pharynx; embryonic tissue; ear; cervix; vascular; stomach; intestine; blood; pancreas; bone; heart; placenta; nerve; ganglia; thyroid; adipose tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p22.2
UniSTS entry: Chr 2 RH69650 [Map Viewer]
UniSTS entry: Chr 2 RH91400
UniSTS entry: Chr 2 RH70529 [Map Viewer]
UniSTS entry: Chr 2 SHGC-12924 [Map Viewer]
UniSTS entry: Cyp1b1
UniSTS entry: Chr 2 CYP1B1_568
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_000104.3 Homo sapiens cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1), mRNA PA
BT020001.1 Homo sapiens cytochrome P450, family 1, subfamily B, polypeptide 1 mRNA, complete cds P
BT019979.1 Homo sapiens cytochrome P450, family 1, subfamily B, polypeptide 1 mRNA, complete cds P
BC012049.1 Homo sapiens cytochrome P450, family 1, subfamily B, polypeptide 1, mRNA (cDNA clone MGC:19842 IMAGE:4662252), complete cds PA
AK312686.1 Homo sapiens cDNA, FLJ93081, Homo sapiens cytochrome P450, family 1, subfamily B, polypeptide 1(CYP1B1), mRNA P
AK297039.1 Homo sapiens cDNA FLJ51600 complete cds, highly similar to Cytochrome P450 1B1 (EC 1.14.14.1) P
AK303862.1 Homo sapiens cDNA FLJ51599 complete cds, highly similar to Cytochrome P450 1B1 (EC 1.14.14.1) P
U03688.1 Human dioxin-inducible cytochrome P450 (CYP1B1) mRNA, complete cds P

EST sequences (10 of 618) [Show all sequences]

AA975127.1 Clone IMAGE:1555912 uncharacterized tissue 3' read A
R15113.1 Clone IMAGE:25594 brain 3' read A
AA994810.1 Clone IMAGE:1635104 kidney 3' read A
AI074672.1 Clone IMAGE:1662890 mixed 3' read
AI090456.1 Clone IMAGE:1691503 heart 3' read
CB049364.1 Clone IMAGE:3271331 prostate 3' read P
CB049365.1 Clone IMAGE:3271331 prostate 5' read P
AI148495.1 Clone IMAGE:1712039 uterus 3' read A
AI150160.1 Clone IMAGE:1751894 testis 3' read PA
BX104039.1 Clone IMAGp998I07590_;_IMAGE:268878 skin


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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