> Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1)
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UGID:154004     UniGene Hs.151777     Homo sapiens (human)   EIF2S1 Order cDNA clone, Links
Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1)

Human protein-coding gene EIF2S1. Represented by 705 ESTs from 312 cDNA libraries. Corresponds to reference sequence NM_004094.4. [UniGene 154004 - Hs.151777]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001105924.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1 isoform 2 M. mulatta 100.0 314
XP_003901994.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1 P. anubis 100.0 314
XP_510016.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1 isoform 3 P. troglodytes 100.0 314
NP_004085.1 EIF2S1 gene product H. sapiens 100.0 314
NP_080390.1 Eif2s1 gene product M. musculus 99.7 314
NP_062229.1 Eif2s1 gene product R. norvegicus 99.7 314
XP_537485.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1 C. lupus familiaris 99.7 314
XP_001499818.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1-like E. caballus 99.7 314
XP_001928385.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1 isoform 2 S. scrofa 99.7 314
NP_787007.1 EIF2S1 gene product B. taurus 99.7 314
XP_004010780.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1 isoform 1 O. aries 99.7 314
XP_002719561.1 PREDICTED: eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa O. cuniculus 99.7 314
NP_001006477.1 EIF2S1 gene product G. gallus 99.7 287
NP_571875.1 eif2s1b gene product D. rerio 97.5 314
NP_001080752.1 eukaryotic translation initiation factor 2 subunit 1 X. laevis 95.9 314
NP_573130.1 eukaryotic translation initiation factor 2alpha D. melanogaster 73.4 304
NP_012540.3 Sui2p S. cerevisiae 66.9 302
XP_961905.1 eukaryotic translation initiation factor 2 alpha subunit N. crassa 64.7 300
XP_001691118.1 eukaryotic initiation factor C. reinhardtii 64.1 326
NP_490930.1 Protein Y37E3.10 C. elegans 64.0 306
NP_565927.1 Eukaryotic translation initiation factor 2 subunit 1 A. thaliana 58.6 324
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
XP_001369967.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1-like M. domestica 99.4 314
XP_003224907.1 PREDICTED: eukaryotic translation initiation factor 2 subunit 1-like isoform 1 A. carolinensis 99.4 314

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; placenta; lung; mixed; embryonic tissue; stomach; mammary gland; larynx; bone; intestine; blood; pancreas; liver; lymph node; kidney; prostate; uterus; muscle; skin; ear; eye; pharynx; thymus; connective tissue; lymph; vascular; bladder; bone marrow; heart; pituitary gland; mouth; thyroid; spleen; trachea; ovary; adipose tissue; cervix; tonsil; ascites; salivary gland; esophagus; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q23.3
UniSTS entry: Chr 14 RH68960 [Map Viewer]
UniSTS entry: Chr 14 HUM0C12G05 [Map Viewer]
UniSTS entry: Chr 14 D14S1214 [Map Viewer]
UniSTS entry: Chr 14 RH91349
UniSTS entry: Chr 14 D14S1305
UniSTS entry: Chr 14 WI-19765 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BX161521.1 human full-length cDNA clone CS0DL010YH08 of B cells (Ramos cell line) of Homo sapiens (human) P
NM_004094.4 Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1), mRNA P
J02645.1 Human translational initiation factor (eIF-2), alpha subunit mRNA, complete cds P
BC002513.2 Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa, mRNA (cDNA clone MGC:1511 IMAGE:3139624), complete cds PA
AK312442.1 Homo sapiens cDNA, FLJ92791, Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1), mRNA P
AK297244.1 Homo sapiens cDNA FLJ51242 complete cds, moderately similar to Eukaryotic translation initiation factor 2 subunit 1 P
D28379.1 Homo sapiens mRNA for eukaryotic initiation factor-2alpha, 5'UTR region
U26032.1 Human translation initiation factor eIF-2alpha mRNA, 3'UTR

EST sequences (10 of 705) [Show all sequences]

AI004266.1 Clone IMAGE:1625994 mixed 3' read A
AI040830.1 Clone IMAGE:1657576 embryonic tissue 3' read A
AI077935.1 Clone IMAGE:1665934 skin 3' read A
AI094496.1 Clone IMAGE:1670499 brain 3' read A
AI143758.1 Clone IMAGE:1705978 heart 3' read A
BX102021.1 Clone IMAGp998I05460_;_IMAGE:229324 mixed P
AI184753.1 Clone IMAGE:1723469 placenta 3' read A
AI192362.1 Clone IMAGE:1722626 placenta 3' read A
AI219231.1 Clone IMAGE:1759410 placenta 3' read A
AI219343.1 Clone IMAGE:1759498 placenta 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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