> Histidine decarboxylase (HDC)
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UGID:131013     UniGene Hs.1481     Homo sapiens (human)   HDC
Histidine decarboxylase (HDC)

Human protein-coding gene HDC. Represented by 47 ESTs from 24 cDNA libraries. Corresponds to reference sequence NM_002112.3. [UniGene 131013 - Hs.1481]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002103.2 HDC gene product H. sapiens 100.0 661
XP_510396.1 PREDICTED: histidine decarboxylase isoform 2 P. troglodytes 99.8 661
NP_032256.3 Hdc gene product M. musculus 92.0 661
NP_001096063.1 hdc gene product D. rerio 74.5 537
NP_001104211.1 dopa decarboxylase (aromatic L-amino acid decarboxylase) X. laevis 59.5 476
NP_523600.5 dopa decarboxylase, isoform D D. melanogaster 55.8 468
NP_495744.1 Protein TDC-1, isoform a C. elegans 52.4 519
NP_001190862.1 tyrosine decarboxylase A. thaliana 47.8 414
XP_001690025.1 aromatic-aminoacid decarboxylase C. reinhardtii 47.7 193
XP_961903.1 hypothetical protein NCU08275 N. crassa 45.6 158
Other hits (2 of 48) [Show all]SpeciesId(%)Len(aa)
XP_001114184.1 PREDICTED: histidine decarboxylase isoform 2 M. mulatta 99.2 661
XP_003900973.1 PREDICTED: histidine decarboxylase P. anubis 99.2 628

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; mixed; mammary gland; prostate; bone marrow; brain; adipose tissue; uncharacterized tissue; lung; intestine; spleen; stomach; thymus; testis; pharynx; uterus; placenta
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q21-q22
UniSTS entry: Chr 15 RH69151
UniSTS entry: Chr 15 D15S1162 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_002112.3 Homo sapiens histidine decarboxylase (HDC), mRNA P
M60445.1 Human histidine decarboxylase (HDC) mRNA, complete cds P
AK027221.1 Homo sapiens cDNA: FLJ23568 fis, clone LNG11092, highly similar to HUMHDC Human histidine decarboxylase (HDC) mRNA PA
BC130527.1 Homo sapiens histidine decarboxylase, mRNA (cDNA clone MGC:163399 IMAGE:40146558), complete cds P
AK308833.1 Homo sapiens cDNA, FLJ98874 P
AK311072.1 Homo sapiens cDNA, FLJ18114 P
AK310479.1 Homo sapiens cDNA, FLJ17521 P
X54297.1 Human mRNA for histidine decarboxylase (EC 4.1.1.22) P
D10088.1 Homo sapiens HisCD alternatively spliced mRNA, insertion sequence region
BC144173.1 Homo sapiens histidine decarboxylase, mRNA (cDNA clone MGC:177710 IMAGE:9052693), complete cds P

EST sequences (10 of 47) [Show all sequences]

BX107942.1 Clone IMAGp998A205538_;_IMAGE:2238235 uncharacterized tissue P
AI695885.1 Clone IMAGE:2238235 uncharacterized tissue 3' read A
AL041199.1 Clone DKFZp434I1516 testis 5' read
CB266975.1 adipose tissue 5' read
CD703337.1 pharynx P
AW198195.1 Clone IMAGE:2705662 pancreas 3' read A
AW204882.1 Clone IMAGE:2719503 mixed 3' read A
BP315792.1 Clone OFR09396 mammary gland 5' read P
DR006262.1 Clone TC118839 prostate 5' read P
AV758763.1 Clone BMFAQD01 bone marrow 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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