> Proliferating cell nuclear antigen (PCNA)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:152583     UniGene Hs.147433     Homo sapiens (human)   PCNA Order cDNA clone, Links
Proliferating cell nuclear antigen (PCNA)

Human protein-coding gene PCNA. Represented by 1025 ESTs from 327 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 152583 - Hs.147433]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001115746.1 PREDICTED: proliferating cell nuclear antigen isoform 1 M. mulatta 100.0 260
XP_003905090.1 PREDICTED: proliferating cell nuclear antigen isoform 1 P. anubis 100.0 260
XP_001165515.1 PREDICTED: proliferating cell nuclear antigen isoform 1 P. troglodytes 100.0 260
NP_872590.1 PCNA gene product H. sapiens 100.0 260
XP_534355.3 PREDICTED: proliferating cell nuclear antigen C. lupus familiaris 100.0 260
XP_001494771.1 PREDICTED: proliferating cell nuclear antigen-like E. caballus 100.0 260
XP_003359931.1 PREDICTED: proliferating cell nuclear antigen S. scrofa 100.0 260
NP_001029666.1 PCNA gene product B. taurus 100.0 260
XP_004014389.1 PREDICTED: proliferating cell nuclear antigen O. aries 100.0 260
NP_071776.1 Pcna gene product R. norvegicus 99.6 260
XP_002710884.1 PREDICTED: proliferating cell nuclear antigen-like O. cuniculus 99.6 260
NP_035175.1 Pcna gene product M. musculus 98.5 260
NP_571479.1 pcna gene product D. rerio 94.6 260
NP_001082364.1 similar to proliferating cell nuclear antigen X. laevis 93.1 260
NP_476905.1 mutagen-sensitive 209, isoform A D. melanogaster 73.5 259
NP_180517.1 proliferating cell nuclear antigen 2 A. thaliana 67.3 263
XP_001703230.1 PCNA proliferating cell nuclear antigen C. reinhardtii 61.7 261
XP_964674.1 proliferating cell nuclear antigen N. crassa 56.0 258
NP_500466.3 Protein PCN-1 C. elegans 49.2 260
Other hits (2 of 48) [Show all]SpeciesId(%)Len(aa)
XP_001372510.1 PREDICTED: proliferating cell nuclear antigen-like M. domestica 98.1 260
NP_989501.1 PCNA gene product G. gallus 97.7 261

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; embryonic tissue; thymus; liver; skin; lung; intestine; kidney; uncharacterized tissue; mixed; uterus; stomach; placenta; mammary gland; pancreas; bladder; prostate; tonsil; salivary gland; adrenal gland; larynx; ascites; blood; eye; connective tissue; bone marrow; lymph node; spleen; heart; bone; parathyroid; muscle; cervix; vascular; pharynx; lymph; mouth; adipose tissue; esophagus; umbilical cord; ovary; nerve; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20pter-p12
UniSTS entry: Chr X STS-M15796
UniSTS entry: Chr X RH68739
UniSTS entry: Chr X RH80338
UniSTS entry: Chr X RH78927 [Map Viewer]
UniSTS entry: Chr X G43531
UniSTS entry: Chr X GDB:450240
UniSTS entry: Chr 20 PMC134733P7
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_182649.1 Homo sapiens proliferating cell nuclear antigen (PCNA), transcript variant 2, mRNA P
NM_002592.2 Homo sapiens proliferating cell nuclear antigen (PCNA), transcript variant 1, mRNA P
BC062439.1 Homo sapiens proliferating cell nuclear antigen, mRNA (cDNA clone MGC:72035 IMAGE:4102284), complete cds PA
CR536501.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0222D for gene PCNA, proliferating cell nuclear antigen; complete cds, incl. stopcodon P
CR541799.1 Homo sapiens full open reading frame cDNA clone RZPDo834C1031D for gene PCNA, proliferating cell nuclear antigen; complete cds, without stopcodon P
BC000491.2 Homo sapiens proliferating cell nuclear antigen, mRNA (cDNA clone MGC:8367 IMAGE:2820036), complete cds PA
AK311014.1 Homo sapiens cDNA, FLJ18056
AK313286.1 Homo sapiens cDNA, FLJ93798, Homo sapiens proliferating cell nuclear antigen (PCNA), mRNA P
AK300558.1 Homo sapiens cDNA FLJ50224 complete cds, highly similar to Proliferating cell nuclear antigen P
M15796.1 Human cyclin protein gene, complete cds P

EST sequences (10 of 1025) [Show all sequences]

AA961262.1 Clone IMAGE:1552145 uncharacterized tissue 3' read A
AA987453.1 Clone IMAGE:1601529 lung 3' read A
AA987916.1 Clone IMAGE:1605119 lung 3' read A
AA988926.1 Clone IMAGE:1602281 lung 3' read A
AA910951.1 Clone IMAGE:1520791 kidney 3' read PA
AI002050.1 Clone IMAGE:1637811 mammary gland 3' read
AI041480.1 Clone IMAGE:1648190 parathyroid 3' read A
AI042167.1 Clone IMAGE:1667993 parathyroid 3' read PA
AI075444.1 Clone IMAGE:1681874 skin 3' read A
AI075412.1 Clone IMAGE:1679357 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help