> Protein phosphatase 2, regulatory subunit B, alpha (PPP2R2A)
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UGID:152131     UniGene Hs.146339     Homo sapiens (human)   PPP2R2A Order cDNA clone, Links
Protein phosphatase 2, regulatory subunit B, alpha (PPP2R2A)

Human protein-coding gene PPP2R2A. Represented by 481 ESTs from 235 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 152131 - Hs.146339]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001371464.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform M. domestica 100.0 456
XP_003902611.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform P. anubis 100.0 456
XP_519670.2 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform 2 P. troglodytes 100.0 456
NP_001171062.1 PPP2R2A gene product H. sapiens 100.0 456
XP_003433382.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform C. lupus familiaris 100.0 456
XP_003364518.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform 2 E. caballus 100.0 456
NP_001178462.1 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform B. taurus 100.0 456
XP_004004222.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform 1 O. aries 100.0 456
NP_082308.1 Ppp2r2a gene product M. musculus 100.0 446
NP_446451.1 Ppp2r2a gene product R. norvegicus 100.0 446
NP_001157492.1 PPP2R2A gene product S. scrofa 100.0 446
NP_001164546.1 LOC100328616 gene product O. cuniculus 100.0 446
XP_001518596.2 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform-like, partial O. anatinus 100.0 293
XP_003227104.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform-like A. carolinensis 99.8 456
XP_003212433.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform-like M. gallopavo 99.8 456
NP_001026057.1 PPP2R2A gene product G. gallus 99.8 446
XP_002193197.1 PREDICTED: similar to mKIAA4213 protein T. guttata 99.5 445
NP_001084138.1 protein phosphatase 2, regulatory subunit B, alpha X. laevis 96.6 443
NP_956070.1 ppp2r2d gene product D. rerio 94.6 447
NP_476881.1 twins, isoform E D. melanogaster 83.2 440
NP_492591.1 Protein SUR-6 C. elegans 75.8 450
XP_963748.2 protein phosphatase PP2A regulatory subunit B N. crassa 66.7 469
XP_001700181.1 PP2A-twin subunit C. reinhardtii 66.5 469
NP_011325.1 Cdc55p S. cerevisiae 64.9 373
NP_849681.1 Protein phosphatase 2A, regulatory subunit PR55 A. thaliana 62.3 491
Other hits (2 of 45) [Show all]SpeciesId(%)Len(aa)
XP_002805342.1 PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform-like M. mulatta 99.3 452
NP_001011075.1 ppp2r2a gene product X. tropicalis 96.4 443

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; placenta; lung; skin; uncharacterized tissue; uterus; mixed; embryonic tissue; eye; adrenal gland; connective tissue; liver; vascular; larynx; pancreas; prostate; spleen; intestine; kidney; lymph node; heart; muscle; mouth; blood; ovary; trachea; mammary gland; pineal gland; bone marrow; stomach; bladder; thymus; ascites; pituitary gland; bone; adipose tissue; cervix; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21.2
UniSTS entry: Chr 8 WI-18898 [Map Viewer]
UniSTS entry: Chr 8 STS-M64929 [Map Viewer]
UniSTS entry: Chr 8 MARC_23873-23874:1028298899:1
UniSTS entry: Chr 4 Ppp2r2a
UniSTS entry: Chr 8 RH102571
UniSTS entry: Chr 8 RH104384
UniSTS entry: Chr 8 PPP2R2A_1255
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

M64929.1 Human protein phosphatase 2A alpha subunit mRNA, complete cds P
AK123721.1 Homo sapiens cDNA FLJ41727 fis, clone HLUNG2015578, highly similar to SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 55 KDA REGULATORY SUBUNIT B, ALPHA ISOFORM PA
NM_002717.3 Homo sapiens protein phosphatase 2, regulatory subunit B, alpha (PPP2R2A), transcript variant 1, mRNA P
CR936829.1 Homo sapiens mRNA; cDNA DKFZp686N05117 (from clone DKFZp686N05117) PA
AY189686.1 Homo sapiens lung cancer-related protein 9 mRNA, complete cds P
AK314823.1 Homo sapiens cDNA, FLJ95701, Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform (PPP2R2A), mRNA P
AK095153.1 Homo sapiens cDNA FLJ37834 fis, clone BRSSN2010019, highly similar to SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 55 KDA REGULATORY SUBUNIT B, ALPHA ISOFORM P
AK303981.1 Homo sapiens cDNA FLJ58665 complete cds, highly similar to Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform P
AL050206.1 Homo sapiens mRNA; cDNA DKFZp586F1523 (from clone DKFZp586F1523) A
NM_001177591.1 Homo sapiens protein phosphatase 2, regulatory subunit B, alpha (PPP2R2A), transcript variant 2, mRNA P
BC041071.1 Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform, mRNA (cDNA clone MGC:52248 IMAGE:5484483), complete cds PA

EST sequences (10 of 481) [Show all sequences]

AA961524.1 Clone IMAGE:1592541 kidney 3' read A
AA969813.1 Clone IMAGE:1572722 kidney 3' read A
AA987296.1 Clone IMAGE:1605045 lung 3' read A
AA995676.1 Clone IMAGE:1606368 kidney 3' read A
AA948570.1 Clone IMAGE:1560458 mixed 3' read
AI032792.1 Clone IMAGE:1647074 parathyroid 3' read
AI033024.1 Clone IMAGE:1654349 mixed 3' read
AI040787.1 Clone IMAGE:1656740 mixed 3' read
T06163.1 Clone HFBDP54 brain
AI126578.1 Clone IMAGE:1735614 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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