> Single-minded homolog 2 (Drosophila) (SIM2)
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UGID:152096     UniGene Hs.146186     Homo sapiens (human)   SIM2 Order cDNA clone, Links
Single-minded homolog 2 (Drosophila) (SIM2)

Human protein-coding gene SIM2. Represented by 47 ESTs from 23 cDNA libraries. EST representation biased toward adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 152096 - Hs.146186]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005060.1 SIM2 gene product H. sapiens 100.0 666
XP_001169453.1 PREDICTED: single-minded homolog 2 isoform 2 P. troglodytes 99.5 666
NP_035507.2 Sim2 gene product M. musculus 92.8 656
NP_001079101.1 single-minded homolog 2 X. laevis 84.8 548
NP_571911.1 sim2 gene product D. rerio 70.6 584
NP_731771.3 single-minded, isoform B D. melanogaster 66.6 377
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_003895560.1 PREDICTED: single-minded homolog 2 P. anubis 98.2 666
XP_849519.2 PREDICTED: single-minded homolog 2 isoform 1 C. lupus familiaris 95.1 551

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; kidney; prostate; ovary; brain; pharynx; thyroid; testis; lung; uterus; uncharacterized tissue; bone; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.13
UniSTS entry: Chr 21 D21S1726E
UniSTS entry: Chr 21 SHGC-87636 [Map Viewer]
UniSTS entry: Sim2
UniSTS entry: Chr 21 PMC153629P1
UniSTS entry: Chr 1 D10S275
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC052313.1 Homo sapiens cDNA clone IMAGE:6650043, partial cds PA
BC067104.1 Homo sapiens cDNA clone IMAGE:6649857, with apparent retained intron PA
NM_009586.2 Homo sapiens single-minded homolog 2 (Drosophila) (SIM2), transcript variant SIM2s, mRNA P
NM_005069.3 Homo sapiens single-minded homolog 2 (Drosophila) (SIM2), transcript variant SIM2, mRNA P
BC110444.2 Homo sapiens single-minded homolog 2 (Drosophila), mRNA (cDNA clone MGC:119447 IMAGE:40007501), complete cds P
X83516.1 H.sapiens RMC03D09 gene, trapped exon
X83515.1 H.sapiens HMC29C01 gene, trapped exon
AJ001859.1 Homo Sapiens mRNA for human SIM2 partial sequence,untranslated 3 prime, DCR1-6.0
AJ001858.1 Homo Sapiens mRNA for human SIM2 partial sequence, DCR1-6.0 P
U80456.1 Human transcription factor SIM2 long form mRNA, complete cds P
U80457.1 Human transcription factor SIM2 short form mRNA, complete cds PA

EST sequences (10 of 47) [Show all sequences]

AA983560.1 Clone IMAGE:1553723 kidney 3' read
AI208499.1 Clone IMAGE:1839129 testis 3' read
AI625864.1 Clone IMAGE:2284071 kidney 3' read
AI681666.1 Clone IMAGE:2272826 lung 3' read
AI913212.1 Clone IMAGE:2295682 kidney 3' read
F02586.1 Clone c-13e10 brain 3' read A
CD701324.1 pharynx
Z40551.1 Clone c-27f12 brain 3' read
F10768.1 Clone c-3jf06 brain 3' read A
BE173346.1 thyroid


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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