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GDP-mannose 4,6-dehydratase (GMDS)
Human protein-coding gene GMDS. Represented by 272 ESTs from 113 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 151502 - Hs.144496]
SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
| Best Hits and Hits from model organisms | Species | Id(%) | Len(aa) |
|
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PREDICTED: GDP-mannose 4,6 dehydratase |
M. mulatta |
100.0 |
371 |
|
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PREDICTED: GDP-mannose 4,6 dehydratase |
P. anubis |
100.0 |
371 |
|
|
GMDS gene product |
H. sapiens |
100.0 |
371 |
|
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PREDICTED: GDP-mannose 4,6 dehydratase |
C. lupus familiaris |
100.0 |
297 |
|
|
PREDICTED: GDP-mannose 4,6 dehydratase |
P. troglodytes |
100.0 |
257 |
|
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PREDICTED: GDP-mannose 4,6 dehydratase |
E. caballus |
99.7 |
341 |
|
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Gmds gene product |
M. musculus |
99.5 |
371 |
|
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GDP-mannose 4,6-dehydratase |
X. laevis |
95.9 |
368 |
|
|
gmds gene product |
D. rerio |
93.2 |
368 |
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GDP-mannose 4,6-dehydratase |
D. melanogaster |
76.8 |
369 |
|
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Protein BRE-1, isoform c |
C. elegans |
74.5 |
367 |
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GDP-mannose 4,6 dehydratase 1 |
A. thaliana |
61.0 |
338 |
| Other hits (2 of 48) [Show all] | Species | Id(%) | Len(aa) |
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Gmds gene product |
R. norvegicus |
99.5 |
371 |
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PREDICTED: GDP-mannose 4,6 dehydratase-like |
M. domestica |
98.8 |
329 |
GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
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EST Profile: | Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this] |
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GEO Profiles: |
Experimental gene expression data (Gene Expression Omnibus). |
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cDNA Sources: |
intestine; testis; uncharacterized tissue; brain; lung; kidney; pancreas; liver; salivary gland; mixed; placenta; pituitary gland; eye; thymus; vascular; connective tissue; prostate; cervix; skin; stomach; embryonic tissue; uterus; lymph; ascites; lymph node; blood; ovary; muscle; esophagus; larynx; mammary gland; bone; spleen |
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
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Chromosome: |
6 |
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Map position: |
6p25 |
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.
mRNA sequences (9)
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AF040260.1 |
Homo sapiens GDP-D-mannose-4,6-dehydratase mRNA, complete cds |
PA |
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NM_001500.3 |
Homo sapiens GDP-mannose 4,6-dehydratase (GMDS), transcript variant 1, mRNA |
PA |
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CR541947.1 |
Homo sapiens full open reading frame cDNA clone RZPDo834A1234D for gene GMDS, GDP-mannose 4,6-dehydratase; complete cds, without stopcodon |
P |
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CR541929.1 |
Homo sapiens full open reading frame cDNA clone RZPDo834B0234D for gene GMDS, GDP-mannose 4,6-dehydratase; complete cds, incl. stopcodon |
P |
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BC000117.1 |
Homo sapiens GDP-mannose 4,6-dehydratase, mRNA (cDNA clone MGC:1739 IMAGE:3351070), complete cds |
PA |
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AK057484.1 |
Homo sapiens cDNA FLJ32922 fis, clone TESTI2006955, moderately similar to GDP-mannose 4,6-dehydratase |
P |
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AK313953.1 |
Homo sapiens cDNA, FLJ94599, highly similar to Homo sapiens GDP-mannose 4,6-dehydratase (GMDS), mRNA |
P |
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NM_001253846.1 |
Homo sapiens GDP-mannose 4,6-dehydratase (GMDS), transcript variant 2, mRNA |
PA |
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AF042377.1 |
Homo sapiens GDP-mannose 4,6 dehydratase mRNA, complete cds |
P |
EST sequences (10 of 272) [Show all sequences]
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AA865823.1 |
Clone IMAGE:1456766 |
kidney |
3' read |
A |
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CB069107.1 |
Clone IMAGE:6364688 |
pancreas |
3' read |
A |
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CB069345.1 |
Clone IMAGE:6364688 |
pancreas |
5' read |
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AI217732.1 |
Clone IMAGE:1844799 |
mixed |
3' read |
A |
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AI244292.1 |
Clone IMAGE:1865874 |
kidney |
3' read |
A |
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AI337360.1 |
Clone IMAGE:2062415 |
intestine |
3' read |
A |
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AI344342.1 |
Clone IMAGE:2062803 |
intestine |
3' read |
PA |
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AI362380.1 |
Clone IMAGE:1979874 |
stomach |
3' read |
A |
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AI362686.1 |
Clone IMAGE:2017338 |
brain |
3' read |
A |
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AI433355.1 |
Clone IMAGE:2138941 |
kidney |
3' read |
A |
Key to Symbols
P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria
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