Endothelin 2 (EDN2)

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UGID:130994 UniGene Hs.1407 Homo sapiens (human) EDN2

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Endothelin 2 (EDN2)

Human protein-coding gene EDN2. Represented by 11 ESTs from 9 cDNA libraries. Corresponds to reference sequence NM_001956.3. [UniGene 130994 - Hs.1407]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_524683.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: uncharacterized protein LOC469298	P. troglodytes	100.0	177
NP_001947.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	EDN2 gene product	H. sapiens	100.0	177
NP_031928.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Edn2 gene product	M. musculus	76.3	172
Other hits (2 of 8) [Show all]		Species	Id(%)	Len(aa)
XP_001084957.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: endothelin-2	M. mulatta	96.1	177
XP_003891730.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: endothelin-2	P. anubis	96.1	177

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources.
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	uncharacterized tissue; mixed; lung; heart; kidney; mammary gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	1
Map position:	1p34
UniSTS entry:	Chr 1	SHGC-74658	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_001956.3	Homo sapiens endothelin 2 (EDN2), mRNA	PA
M65199.1	Human endothelin 2 (ET2) mRNA, complete cds	P
BC034393.1	Homo sapiens endothelin 2, mRNA (cDNA clone MGC:34606 IMAGE:5185394), complete cds	PA
X55177.1	H.sapiens ET-2 mRNA for endothelin-2	P
S63834.1	endothelin-2 {alternatively spliced, clone 484} [human, mRNA Partial, 484 nt]	P
S63835.1	endothelin-2 {alternatively spliced, clone 176} [human, mRNA Partial, 187 nt]
S63836.1	endothelin-2 {alternatively spliced, clone 211} [human, mRNA Partial, 211 nt]
S63837.1	endothelin-2 {alternatively spliced, clone 310} [human, mRNA Partial, 310 nt]	P
S63838.1	endothelin-2 {alternatively spliced, clone 362} [human, mRNA Partial, 362 nt]	P
S63833.1	endothelin-2 {alternatively spliced, clone 432} [human, mRNA Partial, 430 nt]

EST sequences (11)

AI140863.1	Clone IMAGE:1693357	heart	3' read	A
BX119098.1	Clone IMAGp998B144300_;_IMAGE:1693357	heart
AI628621.1	Clone IMAGE:2285094	kidney	3' read	A
AW276532.1	Clone IMAGE:2760181	lung	3' read	A
AW452560.1	Clone IMAGE:3069828	uncharacterized tissue	3' read	A
AW974166.1		uncharacterized tissue
CV029659.1		mixed	5' read	P
BI760483.1	Clone IMAGE:5185394	mixed	5' read	P
BI761655.1	Clone IMAGE:5186732	mixed	5' read
BI769422.1	Clone IMAGE:5204242	mixed	5' read
AA570005.1	Clone IMAGE:1071516	mammary gland	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria