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UGID:150894     UniGene Hs.138378     Homo sapiens (human)   CASP4 Order cDNA clone, Links
Caspase 4, apoptosis-related cysteine peptidase (CASP4)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_508729.2 PREDICTED: caspase 4 isoform 2 P. troglodytes 100.0 376
NP_001216.1 caspase 4 isoform alpha precursor H. sapiens 100.0 376
NP_788811.1 caspase 4 precursor B. taurus 100.0 376
XP_001471646.1 PREDICTED: hypothetical protein M. musculus 66.8 372
NP_001081223.1 xice-a protein precursor X. laevis 48.0 380

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; placenta; liver; mixed; brain; pancreas; uterus; kidney; heart; mammary gland; bone; intestine; spleen; lymph node; muscle; vascular; eye; stomach; pharynx; bone marrow; skin; blood; thymus; uncharacterized tissue; mouth; connective tissue; embryonic tissue; prostate; larynx; amniotic fluid; testis; ovary; bladder; trachea; parathyroid; cervix; lymph; ascites; salivary gland; adipose tissue; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q22.2-q22.3
UniSTS entry: Chr 11 RH16178
UniSTS entry: (n/a)
UniSTS entry: Chr 11 D11S4641
UniSTS entry: Chr 11 D11S1886
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

AF078533.1 Homo sapiens evolutionarily related interleukin-1beta converting enzyme mRNA, complete cds PA
AL050391.1 Homo sapiens mRNA; cDNA DKFZp586A181 (from clone DKFZp586A181); partial cds PA
NM_001225.3 Homo sapiens caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant alpha, mRNA P
CR622245.1 full-length cDNA clone CS0DI078YE15 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR613155.1 full-length cDNA clone CS0DE009YF10 of Placenta of Homo sapiens (human) P
CR609637.1 full-length cDNA clone CS0CAP004YC07 of Thymus of Homo sapiens (human) P
CR601555.1 full-length cDNA clone CS0DI042YN07 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR596626.1 full-length cDNA clone CS0DI058YC09 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR595643.1 full-length cDNA clone CS0DI052YN12 of Placenta Cot 25-normalized of Homo sapiens (human) P
Z48810.1 H.sapiens mRNA for TX protease precursor PA
U28976.1 Human apoptotic cysteine protease Mih1/TX isoform alpha (mih1/Tx) mRNA, complete cds P
U28977.1 Human apoptotic cysteine protease Mih1/TX isoform beta (mih1/Tx) mRNA, complete cds P
U28978.1 Human apoptotic cysteine protease Mih1/TX isoform gamma (mih1/Tx) mRNA, complete cds P
AK225751.1 Homo sapiens mRNA for caspase 4 isoform gamma precursor variant, clone: FCC135F09 PA
NM_033306.2 Homo sapiens caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant gamma, mRNA P
AK057094.1 Homo sapiens cDNA FLJ32532 fis, clone SMINT2000229, highly similar to CASPASE-4 PRECURSOR (EC 3.4.22.-) P
BC017839.1 Homo sapiens caspase 4, apoptosis-related cysteine peptidase, mRNA (cDNA clone MGC:22515 IMAGE:4699374), complete cds PA
AK304222.1 Homo sapiens cDNA FLJ58874 complete cds, highly similar to Caspase-4 precursor (EC 3.4.22.-) P
AK296081.1 Homo sapiens cDNA FLJ57735 complete cds, highly similar to Caspase-4 precursor (EC 3.4.22.-) P
BC008060.2 Homo sapiens cDNA clone IMAGE:2988427, containing frame-shift errors PA
U28979.1 Human apoptotic cysteine protease Mih1/TX isoform delta (mih1/Tx) mRNA, complete cds P
U25804.1 Human Ich-2 cysteine protease mRNA, complete cds P
U28014.1 Human cysteine protease (ICErel-II) mRNA, complete cds P

EST sequences (10 of 368) [Show all sequences]

AA954293.1 Clone IMAGE:1562276 mixed 3' read A
AA886339.1 Clone IMAGE:1493056 kidney 3' read PA
AA971903.1 Clone IMAGE:1583195 mixed 3' read A
AA977397.1 Clone IMAGE:1589059 kidney 3' read PA
AA991681.1 Clone IMAGE:1622011 embryonic tissue 3' read PA
AI038251.1 Clone IMAGE:1672644 mixed 3' read PA
AI091781.1 Clone IMAGE:1694142 heart 3' read PA
AI128269.1 Clone IMAGE:1714598 placenta 3' read PA
AI128358.1 Clone IMAGE:1714655 placenta 3' read PA
AI128505.1 Clone IMAGE:1714115 placenta 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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